Protein Alignment pHCl-2 and Gabra2

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Alignment Length: 456
• Identity: 126/456 - (27%)
• Similarity: 205/456 - (44%)
• Gaps: 91/456 - (19%)

  Fly    85 YDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRR 149
            ||..:.|.:    |:.: .:::...|:.....:..:|:::|:....:.::.|.||.|...:...|
Mouse    53 YDNRLRPGL----GDSI-TEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILR 112

  Fly   150 QPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKF 214
            .    .:.:...:|.|..|..|.:.|.....:..::|..|..:||:|.:.||.....|.|:.:.|
Mouse   113 L----NNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDF 173

  Fly   215 PFDEQKCKTTLESWMYNTTLVQLHW---ETDNPVSFDKQLQLTEYNLIG-SLYNESIRVSNESYM 275
            |.|...|.....|:.|.|:.|...|   .:|:........:|.:|:|:| |:..|:|:.|.
Mouse   174 PMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSST---- 234

  Fly   276 SHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSF 340
                  |.|::::....|.|::||:||..:||.||.|.:|.|||||..:..||||..|.||:|:.
Mouse   235 ------GEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM 293

  Fly   341 ITLSLSQENNLMKVSYVTMSEVWFL-VCTIFIFGSLVEFAFVNTIWRRN---------NDLQLKK 395
            .|||:|..|:|.||:|.|..: ||: ||..|:|.:|:|||.||...:|.         ||.:.:|
Mouse   294 TTLSISARNSLPKVAYATAMD-WFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEK 357

  Fly   396 -----RTTKYIVK-STFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGG 454
                 :...|.|. :.:.|:|.|         |..:||:|.::
Mouse   358 GSVMIQNNAYAVAVANYAPNLSK---------DPVLSTISKSA---------------------- 391

  Fly   455 SLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALF 519
                             :|.|.:...:.|||:  |..|...||. |||..|.|||:.|..||.::
Mouse   392 -----------------TTPEPNKKPENKPAE--AKKTFNSVSK-IDRMSRIVFPVLFGTFNLVY 436

  Fly   520 W 520
            |
Mouse   437 W 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	126/456 (28%)
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	126/456 (28%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	47/214 (22%)
		Cys-loop	166..180	CDD:349836	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		5/59 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000