Protein Alignment pHCl-2 and LOC1281130

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_321068.3
• Gene: LOC1281130 / 1281130
• VectorBaseID: AGAMI1_001548
• Length: 212
• Species: Anopheles gambiae
• Alignment Length: 282
• Identity: 72/282 - (25%)
• Similarity: 127/282 - (45%)
• Gaps: 78/282 - (27%)

  Fly   243 NPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLE---GNYSIISFTVLLTREVGYYVIDY 304
            :|:..:.:::|.:           :.:|| :|.:..::|   ||::.::....|.|.:||::...
Mosquito     3 DPLVVNPEIELPQ-----------LDISN-NYTTDCTIEYSTGNFTCLAVVFNLRRRLGYHLFHT 55

  Fly   305 FLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTI 369
            ::||.:||.:||:|||::.:..|||.|||.|:||:..|.:...:.:|..||||...:||...|::
Mosquito    56 YIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSV 120

  Fly   370 FIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMD 434
            |:|.||:|||.||                                        :.|..::|.:|.
Mosquito   121 FVFLSLMEFAVVN----------------------------------------NYMGPVATKAMK 145

  Fly   435 KTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLW 499
                                ..|.||.:.::| .::...::...||:.....||.  ..:|.:|.
Mosquito   146 --------------------GYSDEDLSEAID-FNKNGYNKDHRSSEVPRYDTFC--HGRETALC 187

  Fly   500 IDRKMRFVFPLSFIVFNALFWT 521
            ||:..||.||.||.:.|..:||
Mosquito   188 IDKFSRFFFPFSFFILNVTYWT 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	72/282 (26%)
LOC1281130	XP_321068.3	LGIC_ECD	<1..47	CDD:475126	9/55 (16%)
		LGIC_TM_anion	50..>136	CDD:349851	37/125 (30%)
		TM1 helix	50..73	CDD:349851	10/22 (45%)
		TM2 helix	77..101	CDD:349851	10/23 (43%)
		TM3 helix	109..135	CDD:349851	12/65 (18%)