Protein Alignment pHCl-2 and Lcch3

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_061518383.1
• Gene: Lcch3 / 1272239
• VectorBaseID: AGAMI1_002473
• Length: 497
• Species: Anopheles gambiae
• Alignment Length: 543
• Identity: 143/543 - (26%)
• Similarity: 243/543 - (44%)
• Gaps: 125/543 - (23%)

  Fly    53 LSQSTVNNCPSLKNAESMA------LMELLTRLTAPCRYDRMVPPVVHNKDGE--EVPMDI-YAR 108
            |:...:||.....:..|||      :.:.::|:..  .||..:.|   |..||  .|.||: .|.
Mosquito    10 LNSVQLNNALRSVHQRSMAAGRLENVTQTISRILE--GYDIRLRP---NFGGEPLHVGMDLTIAS 69

  Fly   109 FYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYL---PNRRQ---PIMGE-----------S 156
            |......|:|     :|:...|...:.|.||||:::.   .|::.   .||.|           .
Mosquito    70 FDAISEVNMD-----YTITMYLNQYWKDERLAFNAFALWGDNQKDQTGEIMIEDDGANDVITLSG 129

  Fly   157 ELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKC 221
            :..:.:|||..|..|::.|.:...:.:::|..:..:|.|....|...||.|.|:...:|.|.|.|
Mosquito   130 DFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLAGDGAVTYGMRFTTTLACMMDLHYYPLDSQNC 194

  Fly   222 KTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSI 286
            ...:||:.|..:.|.::|.: .|:...::.:|.::.:||  |..:.|....:       .|.|..
Mosquito   195 TVEIESYGYTVSDVVMYWRS-TPIRGVEEAELPQFTIIG--YETNDRKEKLA-------TGIYQR 249

  Fly   287 ISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNL 351
            :|.:..|.|.:||:|...:||||:||.:||||||:..:.|.||..||.||:|:..|:|....::|
Mosquito   250 LSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSL 314

  Fly   352 MKVSYVTMSEVWFLVCTIFIFGSLVEFAFVN-TIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRR 415
            .::|||...:::.::|.:|:|.:|:|:|.|| |.|    ..:.||::.|.          |:..|
Mosquito   315 PRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYW----GARAKKKSKKN----------KEAER 365

  Fly   416 HGYRRTDSTMSTMSTTSMDKTCGPNNTVITIE----TPIIIGGSLSREDSAISLDEQDETSTSES 476
            ..:.:|:.|    ||.|.|       .:|.::    :||   .||.....:.::      :|::|
Mosquito   366 KVFGKTEKT----STCSAD-------DIIELQDIRMSPI---ASLRNRHYSNTI------TTTDS 410

  Fly   477 SDSSKEKP------------------------------------AQTFATMTP--KEVSLWIDRK 503
            .||:|..|                                    |.......|  |:|:: ||:.
Mosquito   411 VDSAKFPPSFRIARSYGSSNRSGLRYRSSRGQGRPKMLHAIKRGASVIKASIPKIKDVNV-IDKY 474

  Fly   504 MRFVFPLSFIVFNALFWTLVYCL 526
            .|.:||:||..|||.:| :.|.|
Mosquito   475 SRVIFPVSFAAFNAGYW-IFYVL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	141/537 (26%)
Lcch3	XP_061518383.1	None