Protein Alignment pHCl-2 and XB5799637

DIOPT Version :10

• Sequence 1: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_031762346.1
• Gene: XB5799637 / 100490720
• XenbaseID: XB-GENE-5799638
• Length: 409
• Species: Xenopus tropicalis
• Alignment Length: 452
• Identity: 119/452 - (26%)
• Similarity: 196/452 - (43%)
• Gaps: 88/452 - (19%)

  Fly    85 YDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRR 149
            |::.:.|...|.     |:.:.....|..:..:...::.:|....|:.|:.|.||.|.|   |:.
 Frog    24 YNKYLRPFFDNG-----PVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDERLCFES---NKS 80

  Fly   150 QPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKF 214
            ..:.|  .|.::||||..|:.:.:.|.:...:.::.|..||||||||.:.|:..|:.|.|:..|:
 Frog    81 LSLDG--RLVELLWVPDTFIVDSKKSFLHDMTVENRLIRIYPNGTVLYALRITTTVACSMDLTKY 143

  Fly   215 PFDEQKCKTTLESWMYNTTLVQLHWETDN-PVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHG 278
            |.|:|.|...||||.|||..|..:|...| .|.....|:|.:|    ::.:....||...|.:
 Frog   144 PMDKQTCTLXLESWSYNTNDVMFYWTRGNDSVRGLDALRLAQY----AVEDHYTSVSEAVYET-- 202

  Fly   279 SLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITL 343
               |.|..:.|...|.|.:.|::::.::|||::|.:||||||:.....|||..:|.||:|:..||
 Frog   203 ---GRYPKLVFHFDLKRNILYFILETYVPSILLVVLSWVSFWISLSSVPARICIGVTTVLTMTTL 264

  Fly   344 SLSQENNLMKVS-YVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFV 407
            .:....:|...: ::...:|:..:|..||||:|:|:|..:.                |.:..
 Frog   265 MMGARTSLPNANCFIKAIDVYLGICFSFIFGALLEYAIAHF----------------YTLHQ--- 310

  Fly   408 PHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETS 472
            ||.|.             ||:.....:.....|.|:                 ||:|..:..:|.
 Frog   311 PHQKN-------------STIKKLVAEDEADMNGTI-----------------SAVSDGQSHQTE 345

  Fly   473 TSESSDSSKEK---PAQ-----------TFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            ..:...:.|:|   |..           .|....|.:    ||...|..|||||::.|..:|
 Frog   346 PPDEIGNGKKKIKSPVDPVLKRLLCVFYCFQVQNPHD----IDNYSRISFPLSFMIINVFYW 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	119/452 (26%)
XB5799637	XP_031762346.1	LIC	2..406	CDD:455710	119/452 (26%)
		LGIC_ECD_GABAAR_pi	36..217	CDD:349805	58/194 (30%)
		Cys-loop	135..150	CDD:349805	6/14 (43%)