Protein Alignment pHCl-2 and gabra2a

DIOPT Version :9

• Sequence 1: NP_001303470.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_009305482.1
• Gene: gabra2a / 100150704
• ZFINID: ZDB-GENE-141216-16
• Length: 451
• Species: Danio rerio
• Alignment Length: 486
• Identity: 135/486 - (27%)
• Similarity: 215/486 - (44%)
• Gaps: 95/486 - (19%)

  Fly    54 SQSTVNNCPSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIYVMKNLD 118
            |::.|:...:.||..:: ...:|.||..  .||..:.|.:.:: ..||..|||...:    ..:.
Zfish    25 SEAEVSGSDAFKNNITL-FTRILDRLLD--GYDNRLRPGLGDR-VTEVKTDIYVTSF----GPVS 81

  Fly   119 SSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAK 183
            .:|:::||....:.|:.|.||.|...:...|.    .:.:...:|.|..|..|.:.|.....:..
Zfish    82 DTDMEYTVDVFFRQRWTDERLKFHGPMNILRL----NNLMASKIWTPDTFFHNGKKSVAHNMTMP 142

  Fly   184 DELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNPVSFD 248
            ::|..|..|||:|.:.||.....|.|:.:.||.|...|.....|:.|..|.|...|..:..:|.:
Zfish   143 NKLLRIMENGTLLYTMRLTVQAECPMHLEDFPMDFHSCPLKFGSYAYTLTEVTYVWTRNATLSVE 207

  Fly   249 ---KQLQLTEYNLIG-SLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSI 309
               ...:|.:|:|:| ::..|:|:.|.          |.|::::....|.|::||:||..:||.|
Zfish   208 VAPDGSRLNQYDLMGQTVGKETIKSST----------GEYTVMTAHFHLKRKIGYFVIQTYLPCI 262

  Fly   310 MIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFL-VCTIFIFG 373
            |.|.:|.|||||..:..||||..|.||:|:..|||:|..|:|.||:|.|..: ||: ||..|:|.
Zfish   263 MTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD-WFIAVCYAFVFS 326

  Fly   374 SLVEFAFVNTIWRRN---------NDLQ-----LKKRTTKYIVKSTFVPHLKKHRRHGYRRTDST 424
            :|:|||.||...:|.         ||.:     :||.....:..:.:.||:.|         ||.
Zfish   327 ALIEFATVNYFTKRGWAWDGKSIVNDKKKETSVMKKNNAYAVAVANYAPHIAK---------DSA 382

  Fly   425 MSTMSTTSMDKTCGPNNTVITIETPIIIGGSLSREDSAISLDEQDETSTSESSDSSKEKPAQTFA 489
            :.|:|.::               ||                            :.||.:|.....
Zfish   383 LPTVSKSA---------------TP----------------------------EPSKAQPVAKET 404

  Fly   490 TMTPKEVSLWIDRKMRFVFPLSFIVFNALFW 520
            ..|...||. |||..|.:||:.|..||.::|
Zfish   405 KKTFNSVSK-IDRMSRIIFPVLFGSFNLVYW 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-2	NP_001303470.1	LIC	46..522	CDD:273305	135/486 (28%)
gabra2a	XP_009305482.1	LIC	17..437	CDD:273305	135/486 (28%)
		Neur_chan_LBD	43..250	CDD:280998	56/227 (25%)
		Neur_chan_memb	257..434	CDD:280999	70/230 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900