Protein Alignment ppk24 and ASIC1

DIOPT Version :9

• Sequence 1: NP_651860.2
• Gene: ppk24 / 43702
• FlyBaseID: FBgn0039839
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_064423.2
• Gene: ASIC1 / 41
• HGNCID: 100
• Length: 574
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 107/533 - (20%)
• Similarity: 173/533 - (32%)
• Gaps: 169/533 - (31%)

  Fly    69 SFHCYSKLVESGRRIQERFFWFVFHITALTVLIA---------FLWGTYTKEQEALVTTMYHPMY 124
            :.|..:.:....|...:|..|.:..:.:|.||:.         |.:...||..|...:
Human    26 TLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQYYFHYHHVTKLDEVAAS------- 83

  Fly   125 PIWKVEFPAISVCSLN--RISQRAAWQYAHNLSGKDPKQRNASHFYDQLKAFMYMYY-------- 179
               ::.|||:::|:||  |.||               ..:|..:...:|.|.:...|
Human    84 ---QLTFPAVTLCNLNEFRFSQ---------------VSKNDLYHAGELLALLNNRYEIPDTQMA 130

  Fly   180 DPSDLMDIDNALRFQSFLDRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIAGRLFDCMDKFET 244
            |...|..:.:...|:||..:        .||.|........:..||.:||...|.:....| |:.
Human   131 DEKQLEILQDKANFRSFKPK--------PFNMREFYDRAGHDIRDMLLSCHFRGEVCSAED-FKV 186

  Fly   245 TLTSHGFCCTFN--YDGRYVNKR-------------DFRQRYFGPDMGLVLTLKTDPS--DNFYK 292
            ..|.:|.|.|||  .|||...|.             |.:|..:.|..|     :||.:  :...|
Human   187 VFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWG-----ETDETSFEAGIK 246

  Fly   293 INGHNGYPDPFSGGVAERVAETGFNTLLPVRAKIFETLPEARSMSPSVRKCLFENEMPW------ 351
            :..|:....||...:...|| .||.|.:..:.:....||.                 ||
Human   247 VQIHSQDEPPFIDQLGFGVA-PGFQTFVACQEQRLIYLPP-----------------PWGTCKAV 293

  Fly   352 ------IFARHYTFSKCISACRAQSVVSLCEC--------VPFSLPHRYIDGSEKRIYCTLQHLA 402
                  .|...|:.:.|...|..:.:|..|.|        .|:..|.:|.:.::..:...::
Human   294 TMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVE--- 355

  Fly   403 CLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTETRYSVRGAMTLGLPTPSQIKGPAR 467
                                      :|..|| :|...|..|||....:|         :|.|::
Human   356 --------------------------KDQEYC-VCEMPCNLTRYGKELSM---------VKIPSK 384

  Fly   468 SNPGPRANNSYGPASSSGSAKGPVHSSSAPAE-LAVVRIYFAETHIQYFRQIIKSAWYETFSTIG 531
                         ||:...||....|.....| :.|:.|:|...:.:...|  |.| ||....:|
Human   385 -------------ASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQ--KKA-YEIAGLLG 433

  Fly   532 NICGIIAGFSLIG 544
            .:......||..|
Human   434 ELLMTPVPFSCHG 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk24	NP_651860.2	ASC	65..551	CDD:279230	107/533 (20%)
ASIC1	NP_064423.2	ENaC	19..556	CDD:273304	107/533 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850