Protein Alignment ppk24 and scnn1a

DIOPT Version :10

• Sequence 1: NP_651860.2
• Gene: ppk24 / 43702
• FlyBaseID: FBgn0039839
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 102/614 - (16%)
• Similarity: 182/614 - (29%)
• Gaps: 217/614 - (35%)

  Fly    55 LSFAAALKDLLQ----NLSFHCYSKLVESGRRIQERFFWFVFHITALTVL---IAFLWGTYTKEQ 112
            :.|.::.::|.:    |.:.|...:||.|.....:..||.|..:....::   ...|:|.|..
 Frog    13 IEFFSSYRELFEFFCSNTTIHGAIRLVCSRSNRMKTAFWLVLFLATFGLMYWQFGLLFGQYFS-- 75

  Fly   113 EALVTTMYHPMYPIW--------KVEFPAISVCSLN---------------RISQRAAWQ-YAHN 153
                       ||:.        |:.|||::||:||               :.:||..:: |.:|
 Frog    76 -----------YPVSINLNVNSDKLPFPAVTVCTLNPYRYKAIQNDLQELDKETQRTLYELYKYN 129

  Fly   154 LSGKD---PKQRNASHFYDQLKAFMYMYYDPSDLMDIDNAL------------------------ 191
            .:|..   |..:........|...:.:....|....:..::
 Frog   130 STGVQGWIPTNQRVRRDRPGLPHLLELVPPGSKTHRVSRSVIEEELQVKRREWNIGFKLCNETGG 194

  Fly   192 --RFQSFLDRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIAGR-----LFDCMDKFETTLTS- 248
              .:|::....|..:|...|:..|.::.:....:       |.|.     :|.|....|:...:
 Frog   195 DCFYQTYTSGVDAIREWYRFHYINILARVPEEAA-------IDGEQLENFIFACRFNEESCTKAN 252

  Fly   249 --------HGFCCTFNYDGRYVNKRDFRQRYFGPDM-----GLVLTLKTDPSDNF---------- 290
                    :|.|.|||      ..|..:...:...|     ||.|.|:|:..|..
 Frog   253 YSHFHHAIYGNCYTFN------QNRSGQSNLWSSSMPGIKNGLTLILRTEQHDYIPLLSSVAGAR 311

  Fly   291 YKINGHN--GYPDPFSGGVAERVAETGFNTLLPVRAKIFETLPEARSMSPSVRKC---------- 343
            ..::||.  .:.|           ::|||....:...|.........|......|
 Frog   312 VLVHGHKEPAFMD-----------DSGFNIPPGMETSIGMKKETVNRMGGKYSDCSEDGSDVDVK 365

  Fly   344 -LFENEMPWIFARHYTFSKCISACRAQSVVSLCEC----VPFSLPHRYIDGSEKR---------- 393
             |||:|        ||...|:.:|...::|..|.|    .|.|....:.|.::.:
 Frog   366 NLFESE--------YTEQVCVRSCFQAAMVERCGCGYAFYPLSPGDEFCDYNKHKSWGHCYYKLI 422

  Fly   394 IYCTLQHLACLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTETRYSVRGAMTLGLPT 458
            |..|...|.|..:                              |...|..:.|.:         |
 Frog   423 IEFTSNKLGCFSK------------------------------CRKPCLVSEYQL---------T 448

  Fly   459 PSQIKGPARSNPG---PRANNSYGPASSSGSAKGPVHSSSAPAELAVVRIYFAETHIQYFRQIIK 520
            ....|.|.|.:..   ...:..|.....:|.||              :.|||.|.:.:..::...
 Frog   449 AGYSKWPNRVSQDWVFHTLSRQYNLTDRNGIAK--------------LNIYFEELNYKTIQESPT 499

  Fly   521 SAWYETFSTIGNICGIIAGFSLIGICELL 549
            .......|.:|:...:..|.|::.:.|:|
 Frog   500 INMVMLLSLLGSQWSLWFGSSVLSVVEML 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk24	NP_651860.2	ASC	65..551	CDD:459966	100/604 (17%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	101/609 (17%)