Protein Alignment ppk24 and mec-4

DIOPT Version :10

• Sequence 1: NP_651860.2
• Gene: ppk24 / 43702
• FlyBaseID: FBgn0039839
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 98/481 - (20%)
• Similarity: 163/481 - (33%)
• Gaps: 141/481 - (29%)

  Fly   148 WQYAHNLSGKDPKQRNASHFYDQLKAFMYMYYDPSDLMDIDNALRFQSFLDR---FDTAKEELFF 209
            |.|   |.|..|.:                  ||:.|    .|:.||...|.   ...|||.:.|
 Worm   387 WTY---LQGGTPTE------------------DPNFL----EAMGFQGMTDEVAIVTKAKENIMF 426

  Fly   210 -------NTRNRMSALTPNCSDMFVSCRIAGRLFDCMDKFETTL-TSHGFCCTFNYDGRYVNKRD 266
                   ..|.|:|...   .::...|...|:..|....|.|.: .:.|.|.|||:: |.||...
 Worm   427 AMATLSMQDRERLSTTK---RELVHKCSFNGKACDIEADFLTHIDPAFGSCFTFNHN-RTVNLTS 487

  Fly   267 FRQRYFGPDMGLVLTLKTDPSDNF---------YKINGHNGYPDPFSGGVAERVAETGFNTLLPV 322
            .|.   ||..||.:.:..:.||..         ..|:....:|.|.:.|.:   |.||:.:...:
 Worm   488 IRA---GPMYGLRMLVYVNASDYMPTTEATGVRLTIHDKEDFPFPDTFGYS---APTGYVSSFGL 546

  Fly   323 RAKIFETLPEARSMSPSVRKCLFENE-MPWIFARH-YTFSKCISACRAQSVVSLCEC--VPFSLP 383
            |.:....||....      .|:.:.: ..:|::.: |:...|..:|..|.|:..|.|  ..|.:|
 Worm   547 RLRKMSRLPAPYG------DCVPDGKTSDYIYSNYEYSVEGCYRSCFQQLVLKECRCGDPRFPVP 605

  Fly   384 H--RYIDGSEKRIYCTLQHLA--CLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTET 444
            .  |:.|.::.        :|  ||           .:|.|..|   .|..:..| .|...|.::
 Worm   606 ENARHCDAADP--------IARKCL-----------DARMNDLG---GLHGSFRC-RCQQPCRQS 647

  Fly   445 RYSVRGAMTLGLPTPSQIKGPARS---------NPGPRANNSYGPASSSGSAKGPVHSSSAPAEL 500
            .|||         |.|..|.|:.|         ......|..|   ..:|
 Worm   648 IYSV---------TYSPAKWPSLSLQIQLGSCNGTAVECNKHY---KENG--------------- 685

  Fly   501 AVVRIYFAETHIQYFRQIIKSAWYETFSTIGNICGIIAGFSLIGICELLFFLAKQLWQACRAELR 565
            |:|.:::.:.:.:...:.....:....:..|...|:..|.|.:..||.:|             |.
 Worm   686 AMVEVFYEQLNFEMLTESEAYGFVNLLADFGGQLGLWCGISFLTCCEFVF-------------LF 737

  Fly   566 AELAHIHVQIRNAQVAEPEAERPMKL 591
            .|.|::..:...:...:.:||:..|:
 Worm   738 LETAYMSAEHNYSLYKKKKAEKAKKI 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk24	NP_651860.2	ASC	65..551	CDD:459966	91/439 (21%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	92/452 (20%)