Protein Alignment ppk24 and Asic2

DIOPT Version :9

• Sequence 1: NP_651860.2
• Gene: ppk24 / 43702
• FlyBaseID: FBgn0039839
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 630
• Identity: 132/630 - (20%)
• Similarity: 215/630 - (34%)
• Gaps: 206/630 - (32%)

  Fly    24 IPNPG--RVARYPPI-RTLAPNHLPGTSAEDTRKLSFAAAL--------KDLLQNLSFHCYSKLV 77
            :..||  |:||..|. ..:|....||......|:|......        :..|..|...|..: .
Mouse    14 LSGPGRFRMAREQPAPAAVAAARQPGGDRSGDRELQGPGVARRGRPSLSRTKLHGLRHMCAGR-T 77

  Fly    78 ESGRRIQERFFWFVFHITALTVLIAFLWGTYTKEQEALVTTMYHP----MYPIW--KVEFPAISV 136
            .:|...|.|..|.:...|:|.:|::  |.:     ..|:..:..|    ::..|  ::.|||::|
Mouse    78 AAGGSFQRRALWVLAFCTSLGLLLS--WSS-----NRLLYWLSFPSHTRVHREWSRQLPFPAVTV 135

  Fly   137 CSLN-----RISQRAAWQYAH-----------------NLSGKDPKQRNASHFYDQLKAFMYMYY 179
            |:.|     |:|:...:...|                 .|.|.:|:::    ::.:|..|. ::.
Mouse   136 CNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQ----WFRKLADFR-LFL 195

  Fly   180 DPSDLMDIDNALRFQSFLDRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIAGRL--------F 236
            .|.....|..|     |:||                  |.....||.:||:..|.|        .
Mouse   196 PPRHFEGISAA-----FMDR------------------LGHQLEDMLLSCKYRGELCGPHNFSSV 237

  Fly   237 DCMDKFETTL-------------------------TSHGFCCTFN--YDGRYVNKR--------- 265
            .|..: |..|                         |.:|.|..||  .||:.:...
Mouse   238 SCPPR-EPALSDPALPRSPEALRWAPGTGHQAPVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGL 301

  Fly   266 ----DFRQRYFGPDMGLVLTLKTDPS--DNFYKINGHNGYPDPFSGGVAERVAETGFNTLLPVRA 324
                |.:|..:.|..|     :|:.:  :...|:..|:....||...:...|| .||.|.:..:.
Mouse   302 EIMLDIQQDEYLPIWG-----ETEETTFEAGVKVQIHSQSEPPFIQELGFGVA-PGFQTFVATQE 360

  Fly   325 KIFETLP----EARSMSPSVRKCLFENEMPWIFARHYTFSKCISACRAQSVVSLCEC----VPFS 381
            :....||    |.||           :||...|...|:.:.|...|..:.:|..|.|    :|..
Mouse   361 QRLTYLPPPWGECRS-----------SEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGD 414

  Fly   382 LPHRYIDGSEKRIYCT-LQHLACLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTETR 445
            .|           :|| .||..|              .|...||..| :|:.|| ||...|..||
Mouse   415 AP-----------FCTPEQHKEC--------------AEPALGLLAE-KDSNYC-LCRTPCNLTR 452

  Fly   446 YSVRGAMTLGLPTPSQIKGPARSNPGPRANNSYGPASSSGSAKGPVHSSSAPAELAVVRIYFAET 510
            |:...:|         :|.|::::.      .|.....:.|.|      .....:.|:.|:|...
Mouse   453 YNKELSM---------VKIPSKTSA------KYLEKKFNKSEK------YISENILVLDIFFEAL 496

  Fly   511 HIQYFRQIIKSAWYETFSTIGNI---CGIIAGFSLIGICELLFFL 552
            :.:...|  |.| ||..:.:|:|   .|:..|.|::.|.||..::
Mouse   497 NYETIEQ--KKA-YEVAALLGDIGGQMGLFIGASILTILELFDYI 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk24	NP_651860.2	ASC	65..551	CDD:279230	121/575 (21%)
Asic2	XP_006532059.1	ASC	64..590	CDD:383197	121/580 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842178
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850