Protein Alignment CAH6 and CA7

DIOPT Version :10

• Sequence 1: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: NP_005173.1
• Gene: CA7 / 766
• HGNCID: 1381
• Length: 264
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 86/272 - (31%)
• Similarity: 139/272 - (51%)
• Gaps: 38/272 - (13%)

  Fly    30 WDY--ETNGQNWGGI--CSTGERQSPISLNVQKSLIVPLPRIVFGNYDVKLRGPLTLLNNGHTAH 90
            |.|  :....:|..:  .:.|:|||||::...:::..|..:.:..:|:..:  .|::.||||:..
Human     7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACM--SLSITNNGHSVQ 69

  Fly    91 VEIPETANGNKPFITGGLLKGRFVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVHRN-EKYGD 154
            |:..:  :.::..:|||.|:|.:..:.||||||.....||||:::.:.|..|:|:||.| :||..
Human    70 VDFND--SDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYST 132

  Fly   155 IDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRV----TK-----YNAKTTIPGGLSL 210
            ..||.:..||:||:||.|:....    .|.::::..||..|    ||     :|.|..:|..
Human   133 FGEAASAPDGLAVVGVFLETGDE----HPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPAS--- 190

  Fly   211 GQMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKL----RDSEGHRLINN 271
                     |.::||.||||||...:||||.|..:.:.:....:.||..|    .|.|...::||
Human   191 ---------RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246

  Fly   272 FRDIQPRNGRPV 283
            ||..||..||.|
Human   247 FRPPQPLKGRVV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	86/272 (32%)
CA7	NP_005173.1	alpha_CA_VII	27..262	CDD:239402	83/252 (33%)