Protein Alignment CAH6 and CA6

DIOPT Version :10

• Sequence 1: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 99/294 - (33%)
• Similarity: 148/294 - (50%)
• Gaps: 42/294 - (14%)

  Fly     9 LLLLLPL-----AYQHTSN-----DHKDESHW--DYETNGQNWGGICSTGERQSPISLNVQKSLI 61
            |:|||.|     ..||.|:     ...||:||  .|...|         |:|||||:|...|...
Human     8 LVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACG---------GQRQSPINLQRTKVRY 63

  Fly    62 VP-LPRIVFGNYDVKLRGPLTLLNNGHTAHVEIPETANGNKPFITGGLLKGRFVAEAFHFHWGSP 125
            .| |..:....|:.: .|...::|||||..:.:|.|.   :..:..|.:   ::|:..|||||..
Human    64 NPSLKGLNMTGYETQ-AGEFPMVNNGHTVQISLPSTM---RMTVADGTV---YIAQQMHFHWGGA 121

  Fly   126 SSR--GSEHSINQQRFDVEMHIVHRNEKYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKV 188
            ||.  ||||:::..|..:|:||||.|.||...|.|::..||:||:...:::...|...:  .|..
Human   122 SSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTY--YSNF 184

  Fly   189 MSALPRVTKYNAKTTIPGGLSLGQMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSS 253
            :|.|..: ||..:.|...||.:..||.. |.:.::||.||||||.|.::|.|.|.:..:.:   |
Human   185 ISHLANI-KYPGQRTTLTGLDVQDMLPR-NLQHYYTYHGSLTTPPCTENVHWFVLADFVKL---S 244

  Fly   254 VSKFWKLRDS-EGHR---LINNFRDIQPRNGRPV 283
            .::.|||.:| ..||   :.|::|..||.|.|.|
Human   245 RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	91/267 (34%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	91/267 (34%)