Protein Alignment CAH6 and CA2

DIOPT Version :10

• Sequence 1: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: NP_000058.1
• Gene: CA2 / 760
• HGNCID: 1373
• Length: 260
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 91/272 - (33%)
• Similarity: 142/272 - (52%)
• Gaps: 37/272 - (13%)

  Fly    29 HWDY-ETNG-QNW--GGICSTGERQSPISLNVQKSLIVPLPRIVFGNYDVKLRGPLTLLNNGHTA 89
            ||.| :.|| ::|  ....:.||||||:.::...:...|..:.:..:||...  .|.:|||||..
Human     4 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQAT--SLRILNNGHAF 66

  Fly    90 HVEIPETANGNKPFITGGLLKGRFVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVHRNEKYGD 154
            :||..::.  :|..:.||.|.|.:....|||||||...:||||:::::::..|:|:||.|.||||
Human    67 NVEFDDSQ--DKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGD 129

  Fly   155 IDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSKVMSALPRV---------TKYNAKTTIPGGLSL 210
            ..:|..:.||:||:|:.||:    ....|||.||:..|..:         |.::.:..:|..|
Human   130 FGKAVQQPDGLAVLGIFLKV----GSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESL-- 188

  Fly   211 GQMLGNVNPRDFFTYRGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKLR-DSEG---HRLINN 271
                      |::||.||||||...:.|||.|..:.:.|....|.||.||. :.||   ..:::|
Human   189 ----------DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDN 243

  Fly   272 FRDIQPRNGRPV 283
            :|..||...|.:
Human   244 WRPAQPLKNRQI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	91/272 (33%)
CA2	NP_000058.1	alpha_CA_I_II_III_XIII	1..259	CDD:239393	91/272 (33%)