Protein Alignment CAH6 and PTPRG

DIOPT Version :10

• Sequence 1: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: XP_016862450.1
• Gene: PTPRG / 5793
• HGNCID: 9671
• Length: 1485
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 80/325 - (24%)
• Similarity: 121/325 - (37%)
• Gaps: 92/325 - (28%)

  Fly    27 ESHWDYE--TNGQNW--GGICSTGERQSPISLNVQKSLI-VPLPRIVFGNYDVKLRGPLTLLNNG 86
            :.:|.|.  ...::|  ..:...|..||||.:..|.:.: .....:....:|.:......:.|.|
Human    57 DPYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTG 121

  Fly    87 HTAHVEIPETANGNKPFITGGLLKGRFVAEAFHFHWG-SPSSRGSEHSINQQRFDVEMHIVHRNE 150
            .|..:.:.:..     |::|..|.|||.||...|||| |..|.|||||||.:||.|
Human   122 KTVAILLKDDY-----FVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPV--------- 172

  Fly   151 KYGDIDEAKNKKDGIAVIGVMLKIVKNPNRIFPGLSK---------VMSALPRVTKYNA------ 200
                  ||::.:.|    .:||.:.:....|..||.|         ......::..||.
Human   173 ------EAEDARGG----DIMLMLSQGMRFILLGLKKEQFEERKSWTTYQSMQIFFYNPDDFDSF 227

  Fly   201 KTTIPGGLSLGQM--LGNVNPRD--------------------------------------FFTY 225
            :|.|.....:|.|  ...|:|||                                      ::.|
Human   228 QTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRY 292

  Fly   226 RGSLTTPLCEQSVTWTVFSQVLPVPYSSVSKFWKL--RDSEGH-----RLINNFRDIQPRNGRPV 283
            .||||||.|.:.|.|.||.:.:|:.|..:..|:.:  .:.:.|     .|.||||..|..:.|.|
Human   293 TGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVV 357

  Fly   284  283
            Human   358  357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	80/325 (25%)
PTPRG	XP_016862450.1	alpha_CARP_receptor_like	67..359	CDD:239396	78/315 (25%)
		FN3	388..478	CDD:238020
		PHA03169	<584..>742	CDD:223003
		R-PTPc-G-1	888..1161	CDD:350505
		R-PTP-G-2	1245..1449	CDD:350508