Protein Alignment CAH6 and CA5B

DIOPT Version :10

• Sequence 1: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: NP_009151.1
• Gene: CA5B / 11238
• HGNCID: 1378
• Length: 317
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 84/253 - (33%)
• Similarity: 137/253 - (54%)
• Gaps: 36/253 - (14%)

  Fly    46 GERQSPISLNVQKSLIVPLPRIVFGNYDVKLRGPLTLL---NNGHTAHVEIPETANGNKPFITGG 107
            |:|||||::..:.|:..|..:.:..:||     |.|.|   |||::..||..::.  :|..|.||
Human    61 GDRQSPINIRWRDSVYDPGLKPLTISYD-----PATCLHVWNNGYSFLVEFEDST--DKSVIKGG 118

  Fly   108 LLKGRFVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVHRNE-KYGDIDEAKNKKDGIAVIGVM 171
            .|:..:..:.||||||:..:.||||:::.:.|..|:|:||.|. ::.:.::|..:::|:|||||.
Human   119 PLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVF 183

  Fly   172 LKIVKNPNRIFPGLSKVMSALPRVTKYNAKTTIPGGLSLGQMLGNVNPR-------DFFTYRGSL 229
            ||:.|:...    |.|::..||.:...:|...          .|:.:|.       |::||.|||
Human   184 LKLGKHHKE----LQKLVDTLPSIKHKDALVE----------FGSFDPSCLMPTCPDYWTYSGSL 234

  Fly   230 TTPLCEQSVTWTVFSQVLPVPYSSVSKFWKLR-DSEGH---RLINNFRDIQPRNGRPV 283
            |||...:||||.:..|.:.|.:..:.:|..|. .|||.   |:::|||.:||...|.|
Human   235 TTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	84/253 (33%)
CA5B	NP_009151.1	alpha_CA	61..296	CDD:469577	84/253 (33%)