DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qless and Pdss1

DIOPT Version :9

Sequence 1:	NP_001287619.1	Gene:	qless / 43697	FlyBaseID:	FBgn0051005	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_003751782.2	Gene:	Pdss1 / 100364990	RGDID:	2319976	Length:	500	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	181/365 - (49%)
Similarity:	259/365 - (70%)	Gaps:	15/365 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LQYSQSSKANLRQHSSVHTQQPA---------GPVREFQIDPYIILDDDLKYFYDDVRYLLKSGT 136
            |:...|:..|:...|..|.:.||         |   |...||:.:...|||..|:|:|..|...|
  Rat   142 LKILTSASPNMHSISQFHQRTPAMCCCSQTQSG---EKYSDPFKLGWRDLKGLYEDIRKELHIST 203

  Fly   137 SQPELDTIASYYFDGQGKALRPMVTMLMAKAINYHLNNESHQLVHKQRQIALFSEMVHSASLVHD 201
            .  ||..::.|||||:|||.||::.:|||:|.|.|.|| |.::..:||.:||.:||:|:|:||||
  Rat   204 R--ELKDMSEYYFDGKGKAFRPIIVVLMARACNIHHNN-SREMQARQRSVALVAEMIHTATLVHD 265

  Fly   202 DVIDQSDFRRGKPSVNALWNHKKVTMAGDYILSIASIMIARLRSDDVTIVLSQILTDLVQGEFMQ 266
            ||||.:..||||.:||.:|..:|..:|||.|||.|||.:||:.:..|..:|:|::.|||:|||:|
  Rat   266 DVIDDASSRRGKHTVNKVWGEQKAVLAGDLILSAASIALARIGNTAVVSLLAQVIEDLVRGEFLQ 330

  Fly   267 LGSRETENERFAHYLTKTYRKTASLIANALKATAVIAQADDNVAEVAFQYGRNIGLAFQLVDDML 331
            |||:|.|||||||||.||::||||||||:.||.:|:...|..|.|:|:|||:|:|:||||:||:|
  Rat   331 LGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQYGKNVGIAFQLIDDVL 395

  Fly   332 DFVSSTEQMGKPTAADLKLGLATAPVLFACEKYPELNPMVMRRFSEPGDVERAFELVHKSHGLEQ 396
            ||.|.::||||||:||||||:||.||||||:::||:|.|:|||||.||||:||.:.|.:|.|::|
  Rat   396 DFTSCSDQMGKPTSADLKLGIATGPVLFACQQFPEMNAMIMRRFSLPGDVDRARQYVLQSDGVQQ 460

  Fly   397 TRFLAKKHCNEAIRLAQELTESPYQKGLQVVADLVINRMK 436
            |.:||:::|::|:|..::|..|..:..|..:::.|:.|.|
  Rat   461 TTYLAQQYCHKAVREIRKLRPSTERDALIQLSESVLTRDK 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qless	NP_001287619.1	Isoprenoid_Biosyn_C1	117..435	CDD:294142	168/317 (53%)
Pdss1	XP_003751782.2	PLN02890	74..500	CDD:178478	180/363 (50%)
Pdss1	XP_003751782.2	Isoprenoid_Biosyn_C1	191..498	CDD:294142	165/309 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353386
Domainoid	1	1.000	309	1.000	Domainoid score	I1292
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5353
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2205
OMA	1	1.010	-	-		QHG54105
OrthoDB	1	1.010	-	-		D381154at2759
OrthoFinder	1	1.000	-	-		FOG0002103
OrthoInspector	1	1.000	-	-		oto97356
orthoMCL	1	0.900	-	-		OOG6_100316
Panther	1	1.100	-	-	LDO	PTHR12001
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1555
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810