DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chp and RLP34

DIOPT Version :9

Sequence 1:	NP_001263137.1	Gene:	chp / 43690	FlyBaseID:	FBgn0267435	Length:	1338	Species:	Drosophila melanogaster
Sequence 2:	NP_001326087.1	Gene:	RLP34 / 820272	AraportID:	AT3G11010	Length:	957	Species:	Arabidopsis thaliana

Alignment Length:	1026	Identity:	245/1026 - (23%)
Similarity:	385/1026 - (37%)	Gaps:	314/1026 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 NKIKIQKPTETFNAV----HYTLLKLDLSGDRNDPTNLQTLRKMRNMRSLSISRLGSSSVGPEDF 444
            |:.:|.||:.|...|    |   .|.:..|:.:|..|.:.:  ..|.:|
plant    51 NEFEIGKPSPTCKMVGIESH---RKTESWGNNSDCCNWEGV--TCNAKS---------------- 94

  Fly   445 KDFGVELEDLQITRASLSGIQSHAFKHVRGLKRL--------DFSENGISSIENDAFHEIGHSLI 501
                .|:.:|.::.:||.| :.|:...:|.|..|        ||.....|||||     :.| |.
plant    95 ----GEVIELNLSCSSLHG-RFHSNSSIRNLHFLTTLDRSHNDFEGQITSSIEN-----LSH-LT 148

  Fly   502 SLKMSHG-YSGSALPAEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKG 565
            ||.:|:. :||..|  ..:.:|:.|..||.|.|..|....:|...|.:|..|.|..||
plant   149 SLDLSYNRFSGQIL--NSIGNLSRLTSLDLSFNQFSGQIPSSIGNLSHLTFLGLSGNR------- 204

  Fly   566 TFQGDIHSKLEEISLRFNHLT--SISQHTFF--------DLEALRKLHLDDNKIDKIERRAFMNL 620
             |.|.|.|.:..:|    |||  .:|.:.||        .|..|..|||..||.......:..||
plant   205 -FFGQIPSSIGNLS----HLTFLGLSGNRFFGQFPSSIGGLSNLTNLHLSYNKYSGQIPSSIGNL 264

  Fly   621 DELEYLSLRGNKINNLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQ 685
            .:|..|.|..|........||.||.:|..||::||:|.          |...|:.:|:
plant   265 SQLIVLYLSVNNFYGEIPSSFGNLNQLTRLDVSFNKLG----------GNFPNVLLNL------- 312

  Fly   686 LMYNSSWSGRNEHGGMYHSNIKILDLSHNNISIIHPGYFRPAEISLTHLHLGY---NSLMNTTRD 747
                              :.:.::.||:|..:    |...|...||::|...|   |:...|...
plant   313 ------------------TGLSVVSLSNNKFT----GTLPPNITSLSNLMAFYASDNAFTGTFPS 355

  Fly   748 VFGNMPHLQWLDLSYNWIH-ELDFDAFKNTKQLQLVFFG-HNYLSDIPQDIFKPVQ----GL--- 803
            ....:|.|.:|.||.|.:. .|:|....:...||.:..| :|::..||..|.|.:.    |:
plant   356 FLFIIPSLTYLGLSGNQLKGTLEFGNISSPSNLQYLNIGSNNFIGPIPSSISKLINLQELGISHL 420

  Fly   804 ----RIVDFS-HNHLRGLP---------------DNLFYNGGMEKLDVSHNMMLKIPSSSLSS-L 847
                |.|||| .:||:.|.               |.|.|...:..||:|.|::.....||:|| .
plant   421 NTQCRPVDFSIFSHLKSLDDLRLSYLTTTTIDLNDILPYFKTLRSLDLSGNLVSATNKSSVSSDP 485

  Fly   848 AALTLCELHLSN-------NFISTIHS---MDLSNK------------FRSLRYLDISYN----- 885
            .:.::..|:||.       ..:.|.|.   :|:||.            ..:|.||::|.|
plant   486 PSQSIQSLYLSGCGITDFPEILRTQHELGFLDVSNNKIKGQVPGWLWTLPNLFYLNLSNNTFIGF 550

  Fly   886 -----------YLLRIDDAVFATMP-------KLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLE 932
                       |||..::.....:|       .|..||||.|.....:.:....|:::|.:|.|.
plant   551 QRPTKPEPSMAYLLGSNNNFTGKIPSFICELRSLYTLDLSDNNFSGSIPRCMENLKSNLSELNLR 615

  Fly   933 NISLS-TVPEIRLKYLREFRLGYNEL-PSIPQELAHNMSNLRMLDLSNNDLTNV-PLMTQALPHL 994
            ..:|| ..||...:.||...:|:|:| ..:|:.|.. .|||.:|::.:|.:.:: |....:|..|
plant   616 QNNLSGGFPEHIFESLRSLDVGHNQLVGKLPRSLRF-FSNLEVLNVESNRINDMFPFWLSSLQKL 679

  Fly   995 RRLMLSGNPITSLNNNSFDG-VNE----DLEMLDISNFRLHYFEYGCLDSLPHLRSLKLTAYSHL 1054
            :.|:        |.:|:|.| :|:    .|.::|||:   ::|.    .|||....::.:..|.|
plant   680 QVLV--------LRSNAFHGPINQALFPKLRIIDISH---NHFN----GSLPTEYFVEWSRMSSL 729

  Fly  1055 EHF----NIPHLLRHHYN--------------IRQLWIE-----APQPFTRIVKKGSGPTQEMQT 1096
            ..:    |:.:|...:|.              :|.|.|.     :...|...:.|..|..:|:..
plant   730 GTYEDGSNVNYLGSGYYQDSMVLMNKGVESELVRILTIYTAVDFSGNKFEGEIPKSIGLLKELHV 794

  Fly  1097 LQLGNPTDLQREMEGHLPSKLTNITFSGPQFTNLNERILRGMRSPYLYMQLFNTSLQALPPNFFK 1161
            |.|.|     ....||:||.:.|:                             |:|::|..:..|
plant   795 LNLSN-----NAFTGHIPSSIGNL-----------------------------TALESLDVSQNK 825

  Fly  1162 YMG----RVRNISLDIRYHNRNLKKIPNPNTGAVPYLPNSVFLTDLKMSHTDLNCDCDLGWVEFW 1222
            ..|    .:.|:|| :.|.|.:    .|..||.||  ....|||
plant   826 LYGEIPQEIGNLSL-LSYMNFS----HNQLTGLVP--GGQQFLT--------------------- 862

  Fly  1223 QRKRRQYICSSQTWTDTVFRTFMNSPC---------QVYGRHNCDEHDDDL 1264
            ||      |||......:|.:.:...|         |.:.....:|.|:||
plant   863 QR------CSSFEGNLGLFGSSLEEVCRDIHTPASHQQFETPQTEEEDEDL 907

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	leucine-rich repeat	84..103	CDD:275380
		LRR_8	102..163	CDD:290566
		leucine-rich repeat	104..128	CDD:275380
		LRR_RI	<128..261	CDD:238064
		leucine-rich repeat	129..152	CDD:275380
		LRR_8	152..212	CDD:290566
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		LRR_8	202..261	CDD:290566
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		LRR_8	326..386	CDD:290566	1/1 (100%)
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		leucine-rich repeat	376..401	CDD:275380	7/20 (35%)
		leucine-rich repeat	426..450	CDD:275378	1/23 (4%)
		LRR_RI	<448..651	CDD:238064	67/221 (30%)
		leucine-rich repeat	451..474	CDD:275380	5/22 (23%)
		LRR_8	473..559	CDD:290566	31/94 (33%)
		leucine-rich repeat	475..524	CDD:275380	18/57 (32%)
		leucine-rich repeat	500..519	CDD:275380	7/19 (37%)
		leucine-rich repeat	525..548	CDD:275380	8/22 (36%)
		leucine-rich repeat	549..574	CDD:275380	8/24 (33%)
		LRR_8	573..633	CDD:290566	21/69 (30%)
		leucine-rich repeat	575..598	CDD:275380	8/32 (25%)
		leucine-rich repeat	599..622	CDD:275380	8/22 (36%)
		LRR_8	622..683	CDD:290566	17/60 (28%)
		leucine-rich repeat	623..646	CDD:275380	8/22 (36%)
		leucine-rich repeat	647..730	CDD:275380	14/82 (17%)
		leucine-rich repeat	648..673	CDD:275380	6/24 (25%)
		leucine-rich repeat	674..705	CDD:275380	1/30 (3%)
		LRR_8	704..763	CDD:290566	16/61 (26%)
		leucine-rich repeat	731..754	CDD:275380	5/25 (20%)
		LRR_8	753..813	CDD:290566	22/73 (30%)
		leucine-rich repeat	755..778	CDD:275380	7/23 (30%)
		leucine-rich repeat	779..802	CDD:275380	8/27 (30%)
		leucine-rich repeat	803..823	CDD:275380	10/42 (24%)
		leucine-rich repeat	852..876	CDD:275380	8/45 (18%)
		LRR_8	854..910	CDD:290566	22/100 (22%)
		LRR_RI	<877..>1006	CDD:238064	39/154 (25%)
		leucine-rich repeat	877..900	CDD:275380	9/45 (20%)
		leucine-rich repeat	901..925	CDD:275380	7/23 (30%)
		leucine-rich repeat	926..946	CDD:275380	7/20 (35%)
		LRR_8	947..1004	CDD:290566	16/58 (28%)
		leucine-rich repeat	947..970	CDD:275380	7/23 (30%)
		leucine-rich repeat	971..993	CDD:275380	5/22 (23%)
		LRR_8	992..1049	CDD:290566	15/61 (25%)
		leucine-rich repeat	994..1014	CDD:275380	5/19 (26%)
		leucine-rich repeat	1019..1042	CDD:275380	7/22 (32%)
RLP34	NP_001326087.1	LRRNT_2	40..91	CDD:311940	11/44 (25%)
		PLN00113	75..>717	CDD:331614	186/739 (25%)
		leucine-rich repeat	123..146	CDD:275380	8/27 (30%)
		leucine-rich repeat	147..170	CDD:275380	8/24 (33%)
		leucine-rich repeat	171..194	CDD:275380	8/22 (36%)
		leucine-rich repeat	195..218	CDD:275380	10/34 (29%)
		leucine-rich repeat	219..242	CDD:275380	6/22 (27%)
		leucine-rich repeat	243..266	CDD:275380	8/22 (36%)
		leucine-rich repeat	267..290	CDD:275380	8/22 (36%)
		leucine-rich repeat	291..314	CDD:275380	9/57 (16%)
		leucine-rich repeat	315..362	CDD:275380	11/50 (22%)
		leucine-rich repeat	388..411	CDD:275380	8/22 (36%)
		leucine-rich repeat	412..437	CDD:275380	8/24 (33%)
		leucine-rich repeat	463..489	CDD:275380	8/25 (32%)
		leucine-rich repeat	490..512	CDD:275380	4/21 (19%)
		leucine-rich repeat	513..536	CDD:275380	3/22 (14%)
		leucine-rich repeat	560..583	CDD:275380	4/22 (18%)
		PLN00113	566..>880	CDD:331614	88/397 (22%)
		leucine-rich repeat	584..608	CDD:275380	7/23 (30%)
		leucine-rich repeat	609..630	CDD:275380	7/20 (35%)
		leucine-rich repeat	631..654	CDD:275380	7/23 (30%)
		leucine-rich repeat	655..678	CDD:275380	5/22 (23%)
		leucine-rich repeat	679..700	CDD:275380	7/28 (25%)
		leucine-rich repeat	701..737	CDD:275380	10/42 (24%)
		leucine-rich repeat	738..791	CDD:275380	8/52 (15%)
		leucine-rich repeat	792..815	CDD:275380	8/56 (14%)
		leucine-rich repeat	816..839	CDD:275380	5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I2000
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050