Protein Alignment chp and Cpn2

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_082180.2
• Gene: Cpn2 / 71756
• MGIID: 1919006
• Length: 547
• Species: Mus musculus
• Alignment Length: 537
• Identity: 134/537 - (24%)
• Similarity: 208/537 - (38%)
• Gaps: 145/537 - (27%)

  Fly   570 DIHSKLEEISLRFNHLTSISQHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLSLRGNKIN 634
            ||...:.:|.......|::....|.....|.|:...:.::..:|..||..|..|:.|.:.|:.::
Mouse    46 DIPPHITDIVFVETAFTTVRTRAFSGSPNLTKVVFLNTQVRHLEPDAFGGLPRLQDLEITGSPVS 110

  Fly   635 NLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHG 699
            ||:...|.||..||.|.:.|::|.....|.|..:..|.:|  .:..||:|.|           .|
Mouse   111 NLSAHIFSNLSSLEKLTLDFDRLAGLPEDLFCHMDILESL--QLQGNQLRTL-----------PG 162

  Fly   700 GMYHS--NIKILDLSHNNISIIHPGYFRPAEISLTHLH---LGYNSLMNTTRDVFGNMPHLQWLD 759
            .::.|  :::.|:|:.|.::.:..|.|:    |||.|.   |..|.|........|::..||.|.
Mouse   163 RLFQSLRDLRTLNLAQNLLTQLPKGAFQ----SLTGLQMLKLSNNMLARLPEGALGSLSSLQELF 223

  Fly   760 LSYNWIHELDFDAFKNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNG 824
            |..|.|.||....|.....|::::..||.:..:|..:|..:..|..:....|.||.||:.||
Mouse   224 LDGNAITELSPHLFSQLFSLEMLWLQHNAICHLPVSLFSSLHNLTFLSLKDNALRTLPEGLF--- 285

  Fly   825 GMEKLDVSHNMMLKIPSSSLSSLAALTLCELHLSNNFISTIHSMDLSNKFRSLRYLDISYNYLLR 889
                   :||..|                 ||||                       :|||.|..
Mouse   286 -------AHNQGL-----------------LHLS-----------------------LSYNQLET 303

  Fly   890 IDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLREFRLGY 954
            |.:..|..:.:|..|.||||....:.:..|..|| .|:||.|::
Mouse   304 IPEGAFTNLSRLVSLTLSHNAITDLPEHVFRNLE-QLVKLSLDS--------------------- 346

  Fly   955 NELPSIPQELAHNMSNLRMLDLSNNDLTNVP-LMTQALPHLRRLMLSGNP---------ITS--- 1006
            |.|.::...|.||:|.|::|:||.|.||.:| .:......|..|.|.|||         :||
Mouse   347 NNLTALHPALFHNLSRLQLLNLSRNQLTTLPGGIFDTNYDLFNLALLGNPWQCDCHLSYLTSWLR 411

  Fly  1007 LNNNSFDGVNEDLEMLDISNFRLHYFEYGCLDSLPHLRSLKLTAYSHLEHFNIPHLLRH------ 1065
            |.||            .|||  .|.|..|     |          ::|:...:|:|.:.
Mouse   412 LYNN------------QISN--THTFCAG-----P----------AYLKGQLVPNLKQEQLICPV 447

  Fly  1066 ---HYNIRQLWIEAPQP 1079
               |.:.|.|.::..:|
Mouse   448 NPGHLSFRALGLDEGEP 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378
		leucine-rich repeat	451..474	CDD:275380
		LRR_8	473..559	CDD:404697
		leucine-rich repeat	475..524	CDD:275380
		leucine-rich repeat	500..519	CDD:275380
		leucine-rich repeat	525..548	CDD:275380
		LRR	<540..>834	CDD:443914	69/268 (26%)
		leucine-rich repeat	549..574	CDD:275380	2/3 (67%)
		leucine-rich repeat	575..598	CDD:275380	3/22 (14%)
		leucine-rich repeat	599..622	CDD:275380	6/22 (27%)
		leucine-rich repeat	623..646	CDD:275380	8/22 (36%)
		leucine-rich repeat	647..730	CDD:275380	20/84 (24%)
		leucine-rich repeat	648..673	CDD:275380	7/24 (29%)
		leucine-rich repeat	674..705	CDD:275380	7/32 (22%)
		LRR	<730..1081	CDD:443914	95/375 (25%)
		leucine-rich repeat	731..754	CDD:275380	7/25 (28%)
		leucine-rich repeat	755..778	CDD:275380	9/22 (41%)
		leucine-rich repeat	779..802	CDD:275380	5/22 (23%)
		leucine-rich repeat	803..823	CDD:275380	8/19 (42%)
		leucine-rich repeat	852..876	CDD:275380	4/23 (17%)
		leucine-rich repeat	877..900	CDD:275380	6/22 (27%)
		leucine-rich repeat	901..925	CDD:275380	9/23 (39%)
		leucine-rich repeat	926..946	CDD:275380	4/19 (21%)
		leucine-rich repeat	947..970	CDD:275380	5/22 (23%)
		leucine-rich repeat	971..993	CDD:275380	8/22 (36%)
		leucine-rich repeat	994..1014	CDD:275380	11/31 (35%)
		leucine-rich repeat	1019..1042	CDD:275380	6/22 (27%)
Cpn2	NP_082180.2	LRRNT	21..52	CDD:214470	2/5 (40%)
		LRR_5	51..>128	CDD:463839	20/76 (26%)
		leucine-rich repeat	75..98	CDD:275380	6/22 (27%)
		LRR 1	98..119		6/20 (30%)
		leucine-rich repeat	99..122	CDD:275380	8/22 (36%)
		LRR	102..395	CDD:443914	100/381 (26%)
		LRR 2	122..143		7/20 (35%)
		leucine-rich repeat	123..146	CDD:275380	7/22 (32%)
		LRR 3	146..167		7/33 (21%)
		leucine-rich repeat	147..170	CDD:275380	8/35 (23%)
		LRR 4	170..191		5/24 (21%)
		leucine-rich repeat	171..194	CDD:275380	7/26 (27%)
		LRR 5	194..215		4/20 (20%)
		leucine-rich repeat	195..218	CDD:275380	5/22 (23%)
		LRR 6	218..239		9/20 (45%)
		leucine-rich repeat	219..242	CDD:275380	9/22 (41%)
		LRR 7	242..263		5/20 (25%)
		leucine-rich repeat	243..266	CDD:275380	5/22 (23%)
		LRR 8	266..287		8/30 (27%)
		leucine-rich repeat	267..290	CDD:275380	10/32 (31%)
		LRR 9	290..311		11/60 (18%)
		leucine-rich repeat	291..314	CDD:275380	11/62 (18%)
		LRR 10	314..335		7/20 (35%)
		leucine-rich repeat	315..338	CDD:275380	9/23 (39%)
		LRR 11	338..359		7/41 (17%)
		leucine-rich repeat	339..360	CDD:275380	8/41 (20%)
		LRR 12	362..383		8/20 (40%)
		leucine-rich repeat	363..382	CDD:275380	8/18 (44%)
		PCC	367..>448	CDD:188093	27/109 (25%)