Protein Alignment chp and LOC5666906

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_001688065.2
• Gene: LOC5666906 / 5666906
• VectorBaseID: AGAMI1_008944
• Length: 489
• Species: Anopheles gambiae
• Alignment Length: 600
• Identity: 133/600 - (22%)
• Similarity: 215/600 - (35%)
• Gaps: 198/600 - (33%)

  Fly   514 LPAEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEI 578
            ||.:......::|.|.....||..:...:|...:.|:.|.|:|||:.::....|.|.:  :||.:
Mosquito    77 LPKKIFETFPAIQYLSSDACHIQKLLGGTFANAQRLQELHLYDNRLTRLNNFVFNGAL--QLEIL 139

  Fly   579 SLRFNHLTSISQHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLSLRGNKINNLADESFQN 643
            ||..|.:..:.:|.|..|..||.|::|:|:::|:....|..|:||:.|.|:.|:|..:.|:.|..
Mosquito   140 SLYNNTIKQLEEHAFDGLGHLRLLYMDENQLEKLPEGLFSGLEELQILELQHNRIKEINDDQFVL 204

  Fly   644 LPKLEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHGGMYHSNIKI 708
            .|.|..|:::.|.:..||......:..|..|  :::.|.:.::...              ..::.
Mosquito   205 CPMLRELNLSANMISTFNMSQLQSLNKLETL--DIARNYLDEVFVT--------------KYLRT 253

  Fly   709 LDLSHNNIS--IIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYNWIHELDFD 771
            |:...|.||  ::..|.|    ..||||:|..|::.| ..::| ...:|..||:|||.:..|||.
Mosquito   254 LNAQENQISRIVMDQGDF----FQLTHLNLSRNNIAN-INNIF-KFRNLIELDVSYNELVTLDFV 312

  Fly   772 AF---KNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNGGMEKLDVSH 833
            .|   ||.|.::|                            :|:...:.||
Mosquito   313 IFAFMKNLKDIKL----------------------------NNNRLWILDN-------------- 335

  Fly   834 NMMLKIPSSSLSSLAALTLCELHLSNNFISTIHSMDLSNKFRSLRYLDISYNYLLRIDDAVFATM 898
                .|||.:                               :|||.|::::|..|.:|.||..|.
Mosquito   336 ----GIPSPA-------------------------------KSLRSLNLAHNKFLYLDLAVLDTF 365

  Fly   899 PKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLREFRLGYNELPSIPQE 963
            |.|..:.| |.              |.||.:.:|                              |
Mosquito   366 PALEYIYL-HG--------------NDLIDMQME------------------------------E 385

  Fly   964 LAHNMSNLRMLDLSNNDLTNVPLMTQALPHLRRLMLSGNPITSLNNNSFDGVNEDLEMLDISNFR 1028
            :..|...|.::...|||...:.||     |:..|:.......|..|.:..              |
Mosquito   386 IEQNFPYLTLVSCDNNDWDCINLM-----HIVTLLERAYVKWSNGNRNCT--------------R 431

  Fly  1029 LHYFEYGCLDSLPHLRSLKLTAYSHLEHFNIPHLLRHHYN----IRQLWIEAPQPFTRIVKKGSG 1089
            .....|.|..|..|          ||.. .|..|.|..|.    |:||.:|..:..:.:
Mosquito   432 PEQHRYICCTSAEH----------HLRE-KIVRLTREIYKSRKMIKQLIMENAELRSEV------ 479

  Fly  1090 PTQEMQTLQLGNPTD 1104
               |||.|    |:|
Mosquito   480 ---EMQYL----PSD 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733	13/49 (27%)
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378
		leucine-rich repeat	451..474	CDD:275380
		LRR_8	473..559	CDD:404697	12/44 (27%)
		leucine-rich repeat	475..524	CDD:275380	2/9 (22%)
		leucine-rich repeat	500..519	CDD:275380	2/4 (50%)
		leucine-rich repeat	525..548	CDD:275380	5/22 (23%)
		LRR	<540..>834	CDD:443914	73/298 (24%)
		leucine-rich repeat	549..574	CDD:275380	8/24 (33%)
		leucine-rich repeat	575..598	CDD:275380	8/22 (36%)
		leucine-rich repeat	599..622	CDD:275380	8/22 (36%)
		leucine-rich repeat	623..646	CDD:275380	7/22 (32%)
		leucine-rich repeat	647..730	CDD:275380	14/84 (17%)
		leucine-rich repeat	648..673	CDD:275380	5/24 (21%)
		leucine-rich repeat	674..705	CDD:275380	2/30 (7%)
		LRR	<730..1081	CDD:443914	73/357 (20%)
		leucine-rich repeat	731..754	CDD:275380	8/22 (36%)
		leucine-rich repeat	755..778	CDD:275380	12/25 (48%)
		leucine-rich repeat	779..802	CDD:275380	1/22 (5%)
		leucine-rich repeat	803..823	CDD:275380	3/19 (16%)
		leucine-rich repeat	852..876	CDD:275380	0/23 (0%)
		leucine-rich repeat	877..900	CDD:275380	9/22 (41%)
		leucine-rich repeat	901..925	CDD:275380	3/23 (13%)
		leucine-rich repeat	926..946	CDD:275380	3/19 (16%)
		leucine-rich repeat	947..970	CDD:275380	2/22 (9%)
		leucine-rich repeat	971..993	CDD:275380	6/21 (29%)
		leucine-rich repeat	994..1014	CDD:275380	3/19 (16%)
		leucine-rich repeat	1019..1042	CDD:275380	4/22 (18%)
LOC5666906	XP_001688065.2	None