DRSC/TRiP Functional Genomics Resources

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Protein Alignment chp and lrrc4cb

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:XP_005166545.1 Gene:lrrc4cb / 564462 ZFINID:ZDB-GENE-080327-5 Length:631 Species:Danio rerio


Alignment Length:700 Identity:146/700 - (20%)
Similarity:258/700 - (36%) Gaps:227/700 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   466 SHAFKHV----RGLK-----------RLDFSENGISSIENDAFHEIGHSLISLKMSHGYSGSALP 515
            |:.|..|    ||||           .|:..:|.|..|:.|:|                      
Zfish    55 SNQFSKVICTRRGLKDVPDGVSTNTRYLNLQDNQIQVIKVDSF---------------------- 97

  Fly   516 AEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISL 580
                :||..|:.|..|.|||.::...:|:.|.:|..|||.|||:..:..|.|  :..|||:|:.|
Zfish    98 ----KHLRHLEILQLSRNHIRNIEIGAFNGLTSLNTLELFDNRLTTIPNGAF--EYLSKLKELWL 156

  Fly   581 RFNHLTSISQHTFFDLEALRKLHLDD-NKIDKIERRAFMNLDELEYLSLRGNKINNLAD-ESFQN 643
            |.|.:.||....|..|.:||:|.|.: .::..|...||..|..|.||:|   .:.||.: .:.|.
Zfish   157 RNNPIESIPSDAFSRLPSLRRLDLGELKRLSYISSGAFQGLSNLRYLNL---GMCNLKEVPNIQP 218

  Fly   644 LPKLEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLMYNSSWSGRNEHGGMYHSNIKI 708
            |.:|:.|:|:.|||.......|..:..|..|                 |        |.|:.::.
Zfish   219 LIRLDELEMSGNQLTVIQPSSFKGLVHLQKL-----------------W--------MMHAQVQT 258

  Fly   709 LDLSHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYN---------- 763
            ::  .|:...:|         ||..|:|.:|:|.....|::..:.|||.:.|.:|          
Zfish   259 IE--RNSFDDLH---------SLRELNLAHNNLTFLPHDLYTPLHHLQRVHLHHNPWNCNCDILW 312

  Fly   764 ---WIHELDFDAFKNTK---------QLQLVFFGHNYLSDIPQDIFK---PVQGLRIVDFSHNHL 813
               |:.|   ....||.         .|:     ..|:.::.|..|:   ||    |::      
Zfish   313 LSWWLRE---TVPTNTSCCARCNSPPSLK-----GRYIGELDQSYFQCYAPV----IIE------ 359

  Fly   814 RGLPDNLFYNGGMEKLDVSHNMMLKIPSSSLSSLAALTLCELHLSNNFISTIHSMDLSNKFR--- 875
              .|.:|....||.       ..||..::|::|::.||      .|..|.|..::.:....:   
Zfish   360 --PPVDLNLTEGMA-------AELKCRTNSVTSVSWLT------PNGSIITHGTLKMRINVQNDG 409

  Fly   876 SLRYLDISY----NYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISL 936
            :|.:.:::.    .|...:.:.:..|... |:|:::             .::||    |....:.
Zfish   410 TLNFTNVTLQDTGTYTCYVSNMLGNTSAS-AILNVT-------------SVDNS----GFSYFTT 456

  Fly   937 STVPEIRLKYLREFRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNVPLMTQALPHLRRLMLSG 1001
            .||..|......|.|        .|.:.:...:       |::.....|:.|:....:       
Zfish   457 VTVETIETPIDGESR--------TPVQPSFGWA-------SSSTTRGTPIATERAYTI------- 499

  Fly  1002 NPITSLN-NNSFDGVNEDLEMLDISNFRLHYFEYGCLDSLPHLRSLKLTAYSHLEHFNIPHLLRH 1065
             |:|.:: :.:.:|:.|.::...|.        .||..::..:.::.|..:..:..       :|
Zfish   500 -PVTEIDIDGALNGLEEVMKTTKII--------IGCFVAITLMAAVMLIIFYKMRK-------QH 548

  Fly  1066 HYNIRQLWIEAPQPFTRIVKKGSGPTQEMQTLQLGNPTDLQR--EMEGHL 1113
            |.                 :...||::.|:.:.:..  ||.|  .||.||
Zfish   549 HQ-----------------QDHDGPSRSMEIISVHE--DLTRVPAMESHL 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380
LRR_8 102..163 CDD:290566
leucine-rich repeat 104..128 CDD:275380
LRR_RI <128..261 CDD:238064
leucine-rich repeat 129..152 CDD:275380
LRR_8 152..212 CDD:290566
leucine-rich repeat 153..177 CDD:275380
leucine-rich repeat 178..201 CDD:275380
LRR_8 202..261 CDD:290566
leucine-rich repeat 202..226 CDD:275380
leucine-rich repeat 227..250 CDD:275380
leucine-rich repeat 251..279 CDD:275380
leucine-rich repeat 280..326 CDD:275380
LRR_8 326..386 CDD:290566
leucine-rich repeat 327..348 CDD:275380
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
leucine-rich repeat 426..450 CDD:275378
LRR_RI <448..651 CDD:238064 60/201 (30%)
leucine-rich repeat 451..474 CDD:275380 3/11 (27%)
LRR_8 473..559 CDD:290566 26/96 (27%)
leucine-rich repeat 475..524 CDD:275380 10/59 (17%)
leucine-rich repeat 500..519 CDD:275380 0/18 (0%)
leucine-rich repeat 525..548 CDD:275380 8/22 (36%)
leucine-rich repeat 549..574 CDD:275380 9/24 (38%)
LRR_8 573..633 CDD:290566 23/60 (38%)
leucine-rich repeat 575..598 CDD:275380 9/22 (41%)
leucine-rich repeat 599..622 CDD:275380 8/23 (35%)
LRR_8 622..683 CDD:290566 17/61 (28%)
leucine-rich repeat 623..646 CDD:275380 8/23 (35%)
leucine-rich repeat 647..730 CDD:275380 14/82 (17%)
leucine-rich repeat 648..673 CDD:275380 7/24 (29%)
leucine-rich repeat 674..705 CDD:275380 4/30 (13%)
LRR_8 704..763 CDD:290566 13/58 (22%)
leucine-rich repeat 731..754 CDD:275380 6/22 (27%)
LRR_8 753..813 CDD:290566 16/84 (19%)
leucine-rich repeat 755..778 CDD:275380 8/44 (18%)
leucine-rich repeat 779..802 CDD:275380 6/25 (24%)
leucine-rich repeat 803..823 CDD:275380 3/19 (16%)
leucine-rich repeat 852..876 CDD:275380 3/26 (12%)
LRR_8 854..910 CDD:290566 8/62 (13%)
LRR_RI <877..>1006 CDD:238064 18/132 (14%)
leucine-rich repeat 877..900 CDD:275380 3/26 (12%)
leucine-rich repeat 901..925 CDD:275380 2/23 (9%)
leucine-rich repeat 926..946 CDD:275380 4/19 (21%)
LRR_8 947..1004 CDD:290566 6/56 (11%)
leucine-rich repeat 947..970 CDD:275380 3/22 (14%)
leucine-rich repeat 971..993 CDD:275380 3/21 (14%)
LRR_8 992..1049 CDD:290566 7/57 (12%)
leucine-rich repeat 994..1014 CDD:275380 2/20 (10%)
leucine-rich repeat 1019..1042 CDD:275380 3/22 (14%)
lrrc4cbXP_005166545.1 LRRNT 48..81 CDD:214470 7/25 (28%)
LRR_8 77..137 CDD:290566 22/85 (26%)
leucine-rich repeat 79..102 CDD:275380 8/48 (17%)
LRR_RI 82..>281 CDD:238064 71/265 (27%)
leucine-rich repeat 103..126 CDD:275380 8/22 (36%)
LRR_8 125..180 CDD:290566 23/56 (41%)
leucine-rich repeat 127..150 CDD:275380 9/24 (38%)
leucine-rich repeat 151..174 CDD:275380 9/22 (41%)
leucine-rich repeat 175..199 CDD:275380 8/23 (35%)
leucine-rich repeat 200..221 CDD:275380 8/23 (35%)
LRR_8 221..280 CDD:290566 19/94 (20%)
leucine-rich repeat 222..245 CDD:275380 7/22 (32%)
leucine-rich repeat 246..269 CDD:275380 7/58 (12%)
leucine-rich repeat 270..291 CDD:275380 6/20 (30%)
LRRCT 302..352 CDD:214507 9/57 (16%)
I-set 355..443 CDD:254352 21/113 (19%)
Ig 372..439 CDD:143165 12/73 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24369
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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