DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chp and cDIP

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster


Alignment Length:463 Identity:116/463 - (25%)
Similarity:191/463 - (41%) Gaps:107/463 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   708 ILDLSHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYNWIHELDFDA 772
            ||.||.|:|.::....||.|. :|..:.|..|.|.......|.|:..||:|||:.|.:..|..|.
  Fly   145 ILLLSDNHIEVLPTKTFRGAG-NLEFIFLNRNKLGKLQAGAFDNLLKLQYLDLTENRLEALAADV 208

  Fly   773 FKNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLRGLPDNLFYNGG----MEKLDVSH 833
            |...|.|:.|....|.|:.|..|:|.....|..|...:|.||.:.:..|.:.|    |:.:|:|:
  Fly   209 FAGLKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNRLREVGEYAFRSRGRHHQMQYVDLSN 273

  Fly   834 N-----MMLKIPSSSLSSLAALTLCELHLSNNFISTIHSMDLS-NKFR--------SLRYLDISY 884
            |     ::|.|.:::|::    ..|.|...|.: .::.::||| |:.|        :|.:|.:..
  Fly   274 NPELVVLLLNINATNLTA----RNCSLDRVNLY-GSVTNVDLSDNRVRELYFPASEALEHLVLRN 333

  Fly   885 NYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLRE 949
            |.|:::  |..:.:|:|..||::.|.:|..:...:                  ..|.:.:..|| 
  Fly   334 NSLVQL--ASLSRVPRLRHLDVADNPNLGQLPDGW------------------RTPHLEMLVLR- 377

  Fly   950 FRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNV-----PLMTQALPHLRRLMLSGNPITSLNN 1009
             ..|..||   |.|....|.||:.||:|.|:||.:     |.:||    |....:.||     |.
  Fly   378 -NTGQMEL---PLEALQGMQNLQKLDISGNNLTEIDPSAFPTLTQ----LTHFYIHGN-----NW 429

  Fly  1010 NSF------------DGVNEDLEMLDISNFRLHYFE-YGCLDSLPHLRSLKLTAYSHLEHFNIPH 1061
            |.|            :|:...::..| .:|...||. ..|:..||....:..::.|.:       
  Fly   430 NCFSLRNIMDVLIRANGIAYTVDNYD-PDFPGEYFHGIACMYRLPEKEGVDSSSSSEI------- 486

  Fly  1062 LLRHHYNIRQLWIEAPQPFTRIVKKGSGPTQEMQTLQLGNPTDLQREMEGHLPSKLTNITFSGPQ 1126
                     ...:|: .|.|     .|....|:..|:     |..:.:..|..||. ::.||  :
  Fly   487 ---------SASVES-SPIT-----SSSDPSEVDKLR-----DELKAVVQHFDSKF-DLIFS--K 528

  Fly  1127 FTNLNERI 1134
            ...|||:|
  Fly   529 LAQLNEQI 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380
LRR_8 102..163 CDD:290566
leucine-rich repeat 104..128 CDD:275380
LRR_RI <128..261 CDD:238064
leucine-rich repeat 129..152 CDD:275380
LRR_8 152..212 CDD:290566
leucine-rich repeat 153..177 CDD:275380
leucine-rich repeat 178..201 CDD:275380
LRR_8 202..261 CDD:290566
leucine-rich repeat 202..226 CDD:275380
leucine-rich repeat 227..250 CDD:275380
leucine-rich repeat 251..279 CDD:275380
leucine-rich repeat 280..326 CDD:275380
LRR_8 326..386 CDD:290566
leucine-rich repeat 327..348 CDD:275380
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
leucine-rich repeat 426..450 CDD:275378
LRR_RI <448..651 CDD:238064
leucine-rich repeat 451..474 CDD:275380
LRR_8 473..559 CDD:290566
leucine-rich repeat 475..524 CDD:275380
leucine-rich repeat 500..519 CDD:275380
leucine-rich repeat 525..548 CDD:275380
leucine-rich repeat 549..574 CDD:275380
LRR_8 573..633 CDD:290566
leucine-rich repeat 575..598 CDD:275380
leucine-rich repeat 599..622 CDD:275380
LRR_8 622..683 CDD:290566
leucine-rich repeat 623..646 CDD:275380
leucine-rich repeat 647..730 CDD:275380 9/21 (43%)
leucine-rich repeat 648..673 CDD:275380
leucine-rich repeat 674..705 CDD:275380
LRR_8 704..763 CDD:290566 20/54 (37%)
leucine-rich repeat 731..754 CDD:275380 6/22 (27%)
LRR_8 753..813 CDD:290566 20/59 (34%)
leucine-rich repeat 755..778 CDD:275380 9/22 (41%)
leucine-rich repeat 779..802 CDD:275380 7/22 (32%)
leucine-rich repeat 803..823 CDD:275380 6/19 (32%)
leucine-rich repeat 852..876 CDD:275380 8/32 (25%)
LRR_8 854..910 CDD:290566 16/64 (25%)
LRR_RI <877..>1006 CDD:238064 34/133 (26%)
leucine-rich repeat 877..900 CDD:275380 5/22 (23%)
leucine-rich repeat 901..925 CDD:275380 5/23 (22%)
leucine-rich repeat 926..946 CDD:275380 1/19 (5%)
LRR_8 947..1004 CDD:290566 22/61 (36%)
leucine-rich repeat 947..970 CDD:275380 8/22 (36%)
leucine-rich repeat 971..993 CDD:275380 10/26 (38%)
LRR_8 992..1049 CDD:290566 14/69 (20%)
leucine-rich repeat 994..1014 CDD:275380 6/31 (19%)
leucine-rich repeat 1019..1042 CDD:275380 6/23 (26%)
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380
LRR_RI 143..407 CDD:238064 81/292 (28%)
leucine-rich repeat 143..166 CDD:275380 9/21 (43%)
LRR_8 166..225 CDD:290566 19/58 (33%)
leucine-rich repeat 167..190 CDD:275380 6/22 (27%)
leucine-rich repeat 191..214 CDD:275380 9/22 (41%)
leucine-rich repeat 215..238 CDD:275380 7/22 (32%)
leucine-rich repeat 239..265 CDD:275380 7/25 (28%)
leucine-rich repeat 266..325 CDD:275380 15/63 (24%)
LRR_8 304..357 CDD:290566 14/54 (26%)
leucine-rich repeat 326..347 CDD:275380 5/22 (23%)
leucine-rich repeat 348..394 CDD:275380 14/68 (21%)
LRR_8 369..428 CDD:290566 23/72 (32%)
LRR_4 393..433 CDD:289563 16/48 (33%)
leucine-rich repeat 395..418 CDD:275380 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453809
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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