DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chp and CG42709

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:NP_001163434.1 Gene:CG42709 / 39453 FlyBaseID:FBgn0261674 Length:458 Species:Drosophila melanogaster


Alignment Length:328 Identity:75/328 - (22%)
Similarity:137/328 - (41%) Gaps:60/328 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   800 VQGLRIVDFSHNHLRGLPDNLFYNGGMEKLDVSHNMMLKIPSSSLSSLAALTLCELHLSNNFIST 864
            ::..:.|..::.||..:|.::.....:  :|:|||::.::.....::|:...  |::|::|.||:
  Fly   100 LEDFKFVQCANAHLTHVPLDMPKTAAI--IDLSHNVIAELRPEDFANLSRAV--EINLNHNLISS 160

  Fly   865 IHSMDLSNKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKL 929
            | ..|:......|:.|.::.|.|.:||...||...:|.:||||:|...:.:|.||:. :..|::.
  Fly   161 I-DKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELTLLDLSNNTITQRLDGSFLN-QPDLVEF 223

  Fly   930 GLENISLSTVPEIRLKYLREFRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNVPLMTQALPHL 994
            ...|.|.:.:||                     :...|||.|.:|.|:.||... .:.|:|...|
  Fly   224 SCVNCSWTELPE---------------------QTFQNMSGLEVLRLNKNDFKQ-QINTKAFSPL 266

  Fly   995 RRLMLSGNPITSLNNNSFDGVNEDLEMLDISNFRLHYFEYGCLD---SLPHLRSLKLTAYSHLEH 1056
            .:::....|  .|...:.:.:...|..:|..:| |:| :..|.:   ..|...||.......|:.
  Fly   267 TKIIKLKLP--ELEQQNIEELCSLLTSIDTISF-LNY-DISCYEFVLGTPFNGSLIYPTEPPLKG 327

  Fly  1057 FNIPHLLRHHYNIRQLWIEAPQP-------------FTRIVKKG--------SG----PTQEMQT 1096
            ...|.::....:..:.....|.|             .|.:||.|        ||    |..|.||
  Fly   328 ITNPPIVASITSTAKPVTATPAPPRSANRNRGKMDNSTELVKAGILSSETSTSGVSVEPPAESQT 392

  Fly  1097 LQL 1099
            .|:
  Fly   393 NQV 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380
LRR_8 102..163 CDD:290566
leucine-rich repeat 104..128 CDD:275380
LRR_RI <128..261 CDD:238064
leucine-rich repeat 129..152 CDD:275380
LRR_8 152..212 CDD:290566
leucine-rich repeat 153..177 CDD:275380
leucine-rich repeat 178..201 CDD:275380
LRR_8 202..261 CDD:290566
leucine-rich repeat 202..226 CDD:275380
leucine-rich repeat 227..250 CDD:275380
leucine-rich repeat 251..279 CDD:275380
leucine-rich repeat 280..326 CDD:275380
LRR_8 326..386 CDD:290566
leucine-rich repeat 327..348 CDD:275380
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
leucine-rich repeat 426..450 CDD:275378
LRR_RI <448..651 CDD:238064
leucine-rich repeat 451..474 CDD:275380
LRR_8 473..559 CDD:290566
leucine-rich repeat 475..524 CDD:275380
leucine-rich repeat 500..519 CDD:275380
leucine-rich repeat 525..548 CDD:275380
leucine-rich repeat 549..574 CDD:275380
LRR_8 573..633 CDD:290566
leucine-rich repeat 575..598 CDD:275380
leucine-rich repeat 599..622 CDD:275380
LRR_8 622..683 CDD:290566
leucine-rich repeat 623..646 CDD:275380
leucine-rich repeat 647..730 CDD:275380
leucine-rich repeat 648..673 CDD:275380
leucine-rich repeat 674..705 CDD:275380
LRR_8 704..763 CDD:290566
leucine-rich repeat 731..754 CDD:275380
LRR_8 753..813 CDD:290566 1/12 (8%)
leucine-rich repeat 755..778 CDD:275380
leucine-rich repeat 779..802 CDD:275380 0/1 (0%)
leucine-rich repeat 803..823 CDD:275380 4/19 (21%)
leucine-rich repeat 852..876 CDD:275380 7/23 (30%)
LRR_8 854..910 CDD:290566 20/55 (36%)
LRR_RI <877..>1006 CDD:238064 34/128 (27%)
leucine-rich repeat 877..900 CDD:275380 8/22 (36%)
leucine-rich repeat 901..925 CDD:275380 9/23 (39%)
leucine-rich repeat 926..946 CDD:275380 5/19 (26%)
LRR_8 947..1004 CDD:290566 11/56 (20%)
leucine-rich repeat 947..970 CDD:275380 2/22 (9%)
leucine-rich repeat 971..993 CDD:275380 7/21 (33%)
LRR_8 992..1049 CDD:290566 12/59 (20%)
leucine-rich repeat 994..1014 CDD:275380 3/19 (16%)
leucine-rich repeat 1019..1042 CDD:275380 6/25 (24%)
CG42709NP_001163434.1 LRR_8 126..182 CDD:290566 15/60 (25%)
leucine-rich repeat 128..147 CDD:275380 5/18 (28%)
leucine-rich repeat 148..171 CDD:275380 7/25 (28%)
LRR_RI <150..225 CDD:238064 25/76 (33%)
LRR_8 171..254 CDD:290566 29/104 (28%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
leucine-rich repeat 196..219 CDD:275380 9/23 (39%)
leucine-rich repeat 220..243 CDD:275380 7/43 (16%)
leucine-rich repeat 244..268 CDD:275380 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453743
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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