DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chp and rdo

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster


Alignment Length:786 Identity:182/786 - (23%)
Similarity:297/786 - (37%) Gaps:221/786 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   481 SENGISSIENDAFHEIGHSLISLKMSHGYSGSALPAEPLRHLTSLQELDFSNNHISSMSDTSFHF 545
            ::.|::|:.:....::...:|.::   |...|......||....|:.|..:::::.::...||..
  Fly    43 TKGGLNSLLSPNELDVDVKVIIIR---GPRNSITIGPALRQFMKLEILRITDSNLPAIGAESFWG 104

  Fly   546 LKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISLRFNHLTSISQHTFFDLEALRKLHLDDNKID 610
            ||.||:|:|..|.|..:.:..|:|  ...|.|:.|..|.:..::..||..|..||:|:|.||.|.
  Fly   105 LKYLRILDLSKNNITNITENNFRG--QDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIV 167

  Fly   611 KIERRAFMNLDELEYLSLRGNKINNLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGTLSNLN 675
            ::.:|.|..|..|:||.|.||.:.:|..:.|:::|:|::|.....||...|...::.:..||.|:
  Fly   168 ELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKINPQMYNLLPLLSELD 232

  Fly   676 VNVSHNQIRQLMYNSSWSGRNEHGGMYHSNIKILD--------------LSHNNISIIHPGYFRP 726
            :                 ||||        .|.||              |..|.:|::....|| 
  Fly   233 L-----------------GRNE--------FKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFR- 271

  Fly   727 AEISLTHLHLGYNSLMNTTRDVFGNMPHLQWLDLSYNWIHELDFDAFKNTKQLQLVFFGHNYLSD 791
            .:.||.||.|.||.|.....|.|..:.:|.:||||||.:..|:..:.::...|..:....|.|.|
  Fly   272 MQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSLSNLLTLNISGNVLMD 336

  Fly   792 IPQ--DIFKPVQGLRIVDFSHNHLRGLPDNLFYNGGMEKLDVSHNMMLKIPSSSLSSLAALTLCE 854
            :.:  :.|:|:                   ::|            ..|.........:..||   
  Fly   337 LREMRETFEPL-------------------IYY------------FFLTCSKLFFQLIPQLT--- 367

  Fly   855 LHLSNNFISTIHSMDLSNKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSF 919
             ||:...:.|: .:.|.:.|:.||||:||.|.|......|.....:|..||||.|:         
  Fly   368 -HLAIADMGTM-PVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQ--------- 421

  Fly   920 MGLENSLIKLGLENISLSTVPEIRLKYLREFRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNV 984
                       |..||..||  :|::.:|..||..|  |.|..| .|           ...|.||
  Fly   422 -----------LHGISEDTV--LRIQGIRNVRLDNN--PLICDE-CH-----------MGKLINV 459

  Fly   985 PLMTQALPHLRRLMLSGN--PI---------TSLNNNSFDGVNEDL-----EMLDISNFRLHYFE 1033
                     :|:|....:  ||         ..:||...:|::..|     |..:.::...::.|
  Fly   460 ---------VRQLQWKWDTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEEQNAASTSYNFLE 515

  Fly  1034 YGCLDSLPHLRS----------LKLTA---------YSHLEHFNIPHLLRHHYNIRQLWI----- 1074
            :|.|::|..|..          |.|.|         |:..:|.|.........|:....|     
  Fly   516 HGGLNTLAILGGIIFVLIAVIILSLVACFSKNRARYYTREDHLNGSESKCLEKNLEATTITTLGN 580

  Fly  1075 -EAPQPFTRIVKKGS-----GPTQEMQTLQLGNPTDLQREMEGHLPSKLTNITFSGPQFTNLNER 1133
             .:|...|.:....|     ||....|.|.| :|.:....:.|....|...|.|:.|    :::|
  Fly   581 GSSPTTTTTLTLATSPAAPNGPKTNGQGLSL-SPANGSTPVHGISDDKGKEINFTFP----VDDR 640

  Fly  1134 IL---RGMRSPYLYMQLFNTSLQALPPNFFKYMGRVRNISLDIRYHNRNLKKIPNPNTGAVPY-- 1193
            :.   ..|.||            ..||                       ::.|:||.|::.|  
  Fly   641 VCTIDELMPSP------------PPPP-----------------------QQHPHPNMGSLMYSV 670

  Fly  1194 --LPNS 1197
              .|||
  Fly   671 SHSPNS 676

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380
LRR_8 102..163 CDD:290566
leucine-rich repeat 104..128 CDD:275380
LRR_RI <128..261 CDD:238064
leucine-rich repeat 129..152 CDD:275380
LRR_8 152..212 CDD:290566
leucine-rich repeat 153..177 CDD:275380
leucine-rich repeat 178..201 CDD:275380
LRR_8 202..261 CDD:290566
leucine-rich repeat 202..226 CDD:275380
leucine-rich repeat 227..250 CDD:275380
leucine-rich repeat 251..279 CDD:275380
leucine-rich repeat 280..326 CDD:275380
LRR_8 326..386 CDD:290566
leucine-rich repeat 327..348 CDD:275380
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
leucine-rich repeat 426..450 CDD:275378
LRR_RI <448..651 CDD:238064 48/169 (28%)
leucine-rich repeat 451..474 CDD:275380
LRR_8 473..559 CDD:290566 18/77 (23%)
leucine-rich repeat 475..524 CDD:275380 7/42 (17%)
leucine-rich repeat 500..519 CDD:275380 3/18 (17%)
leucine-rich repeat 525..548 CDD:275380 5/22 (23%)
leucine-rich repeat 549..574 CDD:275380 8/24 (33%)
LRR_8 573..633 CDD:290566 23/59 (39%)
leucine-rich repeat 575..598 CDD:275380 7/22 (32%)
leucine-rich repeat 599..622 CDD:275380 10/22 (45%)
LRR_8 622..683 CDD:290566 17/60 (28%)
leucine-rich repeat 623..646 CDD:275380 8/22 (36%)
leucine-rich repeat 647..730 CDD:275380 20/96 (21%)
leucine-rich repeat 648..673 CDD:275380 5/24 (21%)
leucine-rich repeat 674..705 CDD:275380 5/30 (17%)
LRR_8 704..763 CDD:290566 23/72 (32%)
leucine-rich repeat 731..754 CDD:275380 9/22 (41%)
LRR_8 753..813 CDD:290566 14/61 (23%)
leucine-rich repeat 755..778 CDD:275380 8/22 (36%)
leucine-rich repeat 779..802 CDD:275380 6/24 (25%)
leucine-rich repeat 803..823 CDD:275380 0/19 (0%)
leucine-rich repeat 852..876 CDD:275380 5/23 (22%)
LRR_8 854..910 CDD:290566 19/55 (35%)
LRR_RI <877..>1006 CDD:238064 36/139 (26%)
leucine-rich repeat 877..900 CDD:275380 9/22 (41%)
leucine-rich repeat 901..925 CDD:275380 6/23 (26%)
leucine-rich repeat 926..946 CDD:275380 6/19 (32%)
LRR_8 947..1004 CDD:290566 13/58 (22%)
leucine-rich repeat 947..970 CDD:275380 8/22 (36%)
leucine-rich repeat 971..993 CDD:275380 3/21 (14%)
LRR_8 992..1049 CDD:290566 15/82 (18%)
leucine-rich repeat 994..1014 CDD:275380 6/30 (20%)
leucine-rich repeat 1019..1042 CDD:275380 6/27 (22%)
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380 5/22 (23%)
leucine-rich repeat 108..131 CDD:275380 8/24 (33%)
LRR_8 131..190 CDD:290566 23/58 (40%)
leucine-rich repeat 132..155 CDD:275380 7/22 (32%)
LRR_RI 151..422 CDD:238064 88/352 (25%)
leucine-rich repeat 156..179 CDD:275380 10/22 (45%)
LRR_8 178..262 CDD:290566 26/108 (24%)
leucine-rich repeat 180..203 CDD:275380 8/22 (36%)
leucine-rich repeat 204..251 CDD:275380 15/71 (21%)
leucine-rich repeat 252..275 CDD:275380 5/23 (22%)
LRR_8 274..334 CDD:290566 20/59 (34%)
leucine-rich repeat 276..299 CDD:275380 9/22 (41%)
LRR_4 298..342 CDD:289563 12/43 (28%)
leucine-rich repeat 300..323 CDD:275380 8/22 (36%)
leucine-rich repeat 388..411 CDD:275380 9/22 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453805
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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