DRSC/TRiP Functional Genomics Resources

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Protein Alignment chp and Lrrc4

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:NP_619623.2 Gene:Lrrc4 / 192198 MGIID:2182081 Length:652 Species:Mus musculus


Alignment Length:657 Identity:142/657 - (21%)
Similarity:240/657 - (36%) Gaps:182/657 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   436 SSSVGPEDFKDF---GVELEDLQITRASLS----GIQSHAFKHVRGLKRLDFSENGISSIENDAF 493
            ::|.||::....   ..:...:..||..||    ||.|:.       :.|:..||.|..|:.|.|
Mouse    37 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNT-------RYLNLMENNIQMIQADTF 94

  Fly   494 HEIGHSLISLKMSHGYSGSALPAEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNR 558
                                      |||..|:.|....|.|..:...:|:.|.:|..|||.||.
Mouse    95 --------------------------RHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNW 133

  Fly   559 IEQVLKGTFQGDIHSKLEEISLRFNHLTSISQHTFFDLEALRKLHLDD-NKIDKIERRAFMNLDE 622
            :..:..|.|  :..|||.|:.||.|.:.||..:.|..:.:|.:|.|.: .|::.|...||..|..
Mouse   134 LTVIPSGAF--EYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 196

  Fly   623 LEYLSLRGNKINNLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGTLSNLNVNVSHNQIRQLM 687
            |:||:|....|.::  .:...|..||.|:|:.|..|......|..:.:|..|  .|.::|:    
Mouse   197 LKYLNLGMCNIKDM--PNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKL--WVMNSQV---- 253

  Fly   688 YNSSWSGRNEHGGMYHSNIKILDLSHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVFGNM 752
               |...||...|:  :::..|:|:|||:|.:....|.|... |..|||.:|. .|...|:.   
Mouse   254 ---SLIERNAFDGL--ASLVELNLAHNNLSSLPHDLFTPLRY-LVELHLHHNP-WNCDCDIL--- 308

  Fly   753 PHLQW-------------------LDLSYNWIHELDFDAFKNTKQLQLVFFGHNYLSDIPQDIFK 798
             .|.|                   :.:...::.|:|..||:.:..         ::.|.|:|   
Mouse   309 -WLAWWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQAAFQCSAP---------FIMDAPRD--- 360

  Fly   799 PVQGLRIVDFSHNHLRGLPDNLFYNGGMEKLDVSHNMM--LKIPSSSLSSLAALTLCELHLSNNF 861
                                          |::|.:.|  ||..:..:||:..|      |.|..
Mouse   361 ------------------------------LNISEDRMAELKCRTPPMSSVKWL------LPNGT 389

  Fly   862 ISTIHSMDLSNKFRSLRYL-----DISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMG 921
            :       ||:..|..|..     .::::.:|.||..|:..|    |.:::.|.:....      
Mouse   390 V-------LSHASRHPRISVLNDGTLNFSRVLLIDTGVYTCM----VTNVAGNSNASAY------ 437

  Fly   922 LENSLIKLGLENISLSTVPEIRLKYL--REFRLGYNELP--SIPQELAHNMSNLRMLDLSNNDLT 982
            |..|..:|...|.|..|...:....:  .:....|..:|  |...:.|:..|            |
Mouse   438 LNVSSAELNTPNFSFFTTVTVETTEISPEDITRKYKPVPTTSTGYQPAYTTS------------T 490

  Fly   983 NVPLMTQALPHLRRLMLSGNPITSLNNNSFDGVNEDLEMLDISNFRLHYFEYGCLDSLPHLRSLK 1047
            .|.:.|..:|  :::.:.....|.....|.|.|.:..:::           .||..::..|.:..
Mouse   491 TVLIQTTRVP--KQVPVPSTDTTDKMQTSLDEVMKTTKII-----------IGCFVAVTLLAAAM 542

  Fly  1048 LTAYSHL 1054
            |..:..|
Mouse   543 LIVFYKL 549

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380
LRR_8 102..163 CDD:290566
leucine-rich repeat 104..128 CDD:275380
LRR_RI <128..261 CDD:238064
leucine-rich repeat 129..152 CDD:275380
LRR_8 152..212 CDD:290566
leucine-rich repeat 153..177 CDD:275380
leucine-rich repeat 178..201 CDD:275380
LRR_8 202..261 CDD:290566
leucine-rich repeat 202..226 CDD:275380
leucine-rich repeat 227..250 CDD:275380
leucine-rich repeat 251..279 CDD:275380
leucine-rich repeat 280..326 CDD:275380
LRR_8 326..386 CDD:290566
leucine-rich repeat 327..348 CDD:275380
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
leucine-rich repeat 426..450 CDD:275378 3/16 (19%)
LRR_RI <448..651 CDD:238064 57/207 (28%)
leucine-rich repeat 451..474 CDD:275380 7/26 (27%)
LRR_8 473..559 CDD:290566 22/85 (26%)
leucine-rich repeat 475..524 CDD:275380 10/48 (21%)
leucine-rich repeat 500..519 CDD:275380 0/18 (0%)
leucine-rich repeat 525..548 CDD:275380 6/22 (27%)
leucine-rich repeat 549..574 CDD:275380 8/24 (33%)
LRR_8 573..633 CDD:290566 22/60 (37%)
leucine-rich repeat 575..598 CDD:275380 8/22 (36%)
leucine-rich repeat 599..622 CDD:275380 8/23 (35%)
LRR_8 622..683 CDD:290566 16/60 (27%)
leucine-rich repeat 623..646 CDD:275380 6/22 (27%)
leucine-rich repeat 647..730 CDD:275380 23/82 (28%)
leucine-rich repeat 648..673 CDD:275380 7/24 (29%)
leucine-rich repeat 674..705 CDD:275380 7/30 (23%)
LRR_8 704..763 CDD:290566 17/77 (22%)
leucine-rich repeat 731..754 CDD:275380 7/22 (32%)
LRR_8 753..813 CDD:290566 9/78 (12%)
leucine-rich repeat 755..778 CDD:275380 6/41 (15%)
leucine-rich repeat 779..802 CDD:275380 3/22 (14%)
leucine-rich repeat 803..823 CDD:275380 0/19 (0%)
leucine-rich repeat 852..876 CDD:275380 4/23 (17%)
LRR_8 854..910 CDD:290566 12/60 (20%)
LRR_RI <877..>1006 CDD:238064 23/137 (17%)
leucine-rich repeat 877..900 CDD:275380 6/27 (22%)
leucine-rich repeat 901..925 CDD:275380 3/23 (13%)
leucine-rich repeat 926..946 CDD:275380 4/19 (21%)
LRR_8 947..1004 CDD:290566 9/60 (15%)
leucine-rich repeat 947..970 CDD:275380 4/26 (15%)
leucine-rich repeat 971..993 CDD:275380 3/21 (14%)
LRR_8 992..1049 CDD:290566 8/56 (14%)
leucine-rich repeat 994..1014 CDD:275380 2/19 (11%)
leucine-rich repeat 1019..1042 CDD:275380 2/22 (9%)
Lrrc4NP_619623.2 LRRNT 45..78 CDD:214470 7/39 (18%)
LRR_8 74..132 CDD:290566 21/90 (23%)
LRR 1 75..96 7/53 (13%)
leucine-rich repeat 76..99 CDD:275380 10/55 (18%)
LRR_RI 91..304 CDD:238064 72/255 (28%)
LRR 2 99..120 5/20 (25%)
leucine-rich repeat 100..123 CDD:275380 6/22 (27%)
LRR 3 123..144 8/22 (36%)
leucine-rich repeat 124..147 CDD:275380 8/24 (33%)
LRR_8 146..207 CDD:290566 22/60 (37%)
LRR 4 147..168 9/20 (45%)
leucine-rich repeat 148..171 CDD:275380 8/22 (36%)
LRR 5 171..193 7/21 (33%)
leucine-rich repeat 172..196 CDD:275380 8/23 (35%)
LRR 6 196..217 5/22 (23%)
leucine-rich repeat 197..218 CDD:275380 6/22 (27%)
LRR_8 218..277 CDD:290566 19/69 (28%)
LRR 7 218..239 7/20 (35%)
leucine-rich repeat 219..242 CDD:275380 7/22 (32%)
LRR 8 242..263 7/29 (24%)
leucine-rich repeat 243..266 CDD:275380 8/33 (24%)
LRR 9 266..287 7/20 (35%)
leucine-rich repeat 267..288 CDD:275380 7/20 (35%)
LRRCT 299..350 CDD:214507 9/55 (16%)
IG_like 358..440 CDD:214653 24/137 (18%)
Ig 369..440 CDD:299845 19/93 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24369
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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