Protein Alignment chp and LOC1279967

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_061513522.1
• Gene: LOC1279967 / 1279967
• VectorBaseID: AGAMI1_001913
• Length: 1326
• Species: Anopheles gambiae
• Alignment Length: 1271
• Identity: 320/1271 - (25%)
• Similarity: 548/1271 - (43%)
• Gaps: 165/1271 - (12%)

  Fly    44 CTYNVMCTCSK--SSTDLGIVHCKNVPFPALPRMVNQSKVFMLHMENTGLREIEPYFLQSTGMYR 106
            |..|.||.|:.  :.|.|..::|..|.....|..:: ..:..:.|..|.:..::....|...:..
Mosquito    47 CPINTMCRCASLPNETALLEINCNEVSLYKFPEFLH-GTIKHIDMSRTFIHNVDDETFQGLRLES 110

  Fly   107 LKISGNHLTEIPDDAFTGLERSLWELILPQNDLVEIPSKSLRHLQKLRHLDLGYNHITHIQHDSF 171
            ||:..|.:.:|.:.:|..::.||..|.|..|.|..:|..||:::..|..|....|:|.|:. .::
Mosquito   111 LKLVDNKIQDISEKSFNFMQHSLVSLDLSDNQLQGLPLDSLKNVHTLSRLVAQRNNIHHLD-GNW 174

  Fly   172 RGLEDSLQTLILRENCISQL---------MSHS-------------------------------- 195
            .||.|||::|.:..|.||::         .:|:
Mosquito   175 GGLADSLRSLHISGNSISEVSFYTHDEKRQNHTAPNSQASIINAKQFSQYPPGTPGMGQQQQQQQ 239

  Fly   196 -------------------FSGLLILETLDLSGNNLFEIDPNVFVDGMPR-LTRLLLTDNILSEI 240
                               |:.|..|..||:|.|.:..|.||.|    |: |..:.|:.||||:.
Mosquito   240 QQQPGATAVNGLQQQGIKPFAKLKKLVWLDISSNRIAHISPNTF----PKSLVTIDLSKNILSQF 300

  Fly   241 PYDALGPLKSLRTLDISHNVIWSLSGNETYEIKASTKLNLDNLHLEYNHIEVLPPNSFKYFDTVN 305
            |...|..|..||.|.:..|:|..|.|:.  :....|::.|:.|.|..|.:|.:||..|.....:.
Mosquito   301 PTAFLEHLHDLRVLSLKDNLIAKLDGSP--DPAGPTRIRLEKLDLSLNLVEEIPPLLFNGSVRIK 363

  Fly   306 RTFFDGNPIHTLREDAFKPARIREIYMRYCGLTNISPVAFDSLVNSLQILDLSGNNLTKLHHKLF 370
            ...||.|.|..|..|.|:...|..:.:.:..:.:|...||.||.|||:.|||..|.||.:...:
Mosquito   364 AINFDKNFIRHLEADTFQGLNIVHMVLAFNFIESIDDGAFGSLENSLEYLDLERNRLTVVPTAI- 427

  Fly   371 NNFDVLRVISMRDNKIKIQKPTETFNAVHYTLLKLDLSGDRNDPTNLQTLRKMRNMRSLSISRLG 435
            ...:.||.:.:..|:: ...|.:....:..||..|.|||:......:..|   .|...||...:|
Mosquito   428 GRLNRLRYLYLTSNEL-THIPDQPEPLLPTTLKVLSLSGNNFTAIPVDAL---SNCTELSYLNMG 488

  Fly   436 SSSVGPED---FKDFGVELEDLQITRASLSGIQSHAFKHVRGLKRLDFSENGISSIENDAFHEIG 497
            .:.:...:   |..:|..|:.|.:....::.:...||..:..:|.:..|.|.|..:..:.|..:.
Mosquito   489 YNKIADIEENAFAGWGSNLQTLLLRNNKITSLNYGAFNGLDTIKEISLSFNDIHYVHPNVFDNVS 553

  Fly   498 HSLISLKMSHGYSGSALPAEPLRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQV 562
            .:|..|::|.|......|.|.|..||.|..|...||::.::.|.:...|..|..:.|..|||..:
Mosquito   554 STLKILELSFGIYREEYPGEALAVLTELMWLGLDNNNLKTLPDGALSTLGQLTYVNLAFNRIVAI 618

  Fly   563 LKGTFQGDIHSKLEEISLRFNHLTSISQHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLS 627
            .:..|:.|||..|.||.|.||.|..:...||..||.::.::|..||:..:::.|..:|..|.|:.
Mosquito   619 PRWLFRSDIHRNLVEIDLSFNQLEDLPSATFDSLELIQIINLSSNKLRTMQKNALHDLPYLTYVD 683

  Fly   628 LRGNKINNLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGTLSN-LNVNVSHN-------QIR 684
            |..|.:.|:::.:|..||.|..:|:..|:|...:...|.||...:. :.:|:|.|       .:.
Mosquito   684 LSYNALQNISEGAFSYLPSLLSVDLMHNELATLSLKVFRQVSNATTPMRLNISSNAIEFLDGDVN 748

  Fly   685 QLMYNSSWSGRNEHGGMYHSNIKILDLSHNNISIIHPGYFRPAEISLTHLHLGYNSLMNTTRDVF 749
            .|:|                 :..||.|||.:.  ....||....||..|:|.:|:........|
Mosquito   749 SLLY-----------------VYSLDASHNQLQ--DTTVFRALAFSLRILYLNWNNFTTLGNHAF 794

  Fly   750 GNMPHLQWLDLSYNWIHELDFDAFKNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNHLR 814
            |::..|:.|:|::|.|..|...:|.....||.....||.:..:..:.|.|::.||::..::|.||
Mosquito   795 GDLQILEILNLAHNNISSLRRRSFAGLMNLQEFDLSHNRIESLQIEQFSPLKKLRLLRLNNNRLR 859

  Fly   815 GLPDNLFYNGGMEKLDVSHNMMLKIPSSSLSSLAALTLCELHLSNNFISTIHS-MDLSNKFRSLR 878
            .:|.:.|.|..:|.||:|:|..:...:::.:.: ..||..:...||.:..:.. |..|.:|  |.
Mosquito   860 TIPRDTFLNTRIEFLDLSNNQFVAWQATAFADI-GFTLRSIQFDNNLLEFLDPYMFTSTQF--LL 921

  Fly   879 YLDISYNYLLRIDDAVFATMPKLAVLDLSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIR 943
            .|:::.|.:..|.|..||.:..|.|||||:|:.:.|..:........|..|.|.:..:..:|.:.
Mosquito   922 ELNLAGNLIKLIPDNAFANLNNLTVLDLSYNQLMPVNFRELFVNVPRLRVLSLRSTGIYRLPTLA 986

  Fly   944 LKYLREFRLGYNELPSIPQELAHNMSNLRMLDLSNNDLTNVP-LMTQALPHLRRLMLSGNPITSL 1007
            |..|....:..|.|..|..:  ..:..||.|.:..|.:.|:. |:....|.||.|.:|.|||..:
Mosquito   987 LPQLASLDVSNNNLQEIDSQ--EELFFLRELHIQENKVNNISNLLRNLPPALRVLDISRNPIRKI 1049

  Fly  1008 NNNSFDGVNEDLEMLDISNFRLHYFEYGCLDSLPHLRSLKLTAYSHLEHFNIPHLLRHHYNIRQL 1072
            :.:.| .::..||.|.|.:.::                           .| |.:....:|:::|
Mosquito  1050 SFHDF-ALSRRLEELFIEDIKI---------------------------VN-PDIFIKLHNLKKL 1085

  Fly  1073 WIEAPQPFTRIVKKGSGPTQEMQTL---QLGNPTDLQREMEGHLPSKLTNITFSGPQFTNLNERI 1134
            .|.|...|:.:|.|..|..:...|:   .||:.....|.   |..:||..:..:|.:..:::...
Mosquito  1086 RISAQHNFSELVSKLRGLQELYVTIYDEHLGDGLFTSRM---HANTKLNVVEITGRRLVSISSNA 1147

  Fly  1135 LRGM-RSPYLYMQLFNTSLQALPPNFFKYMGRVRNISLDIRYHNRNLKKIPNPNTGAVPYLPNS- 1197
            .:|: |:..|.:::.||.:..|||..|..:..:..:|:|:   :.||.....|::    :.||:
Mosquito  1148 FQGLARNHDLKLRIRNTMVNDLPPGVFYALKYIPRLSIDL---SDNLLAALAPDS----FYPNAS 1205

  Fly  1198 --------VFLTDLKMSHTDLNCDCDLGWVEFWQRK 1225
                    ..:..|.:|:..|.|:|.|.|:..|.|:
Mosquito  1206 SWDAVGTRSVIGGLDVSNNPLQCECGLVWLGHWLRR 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914	74/296 (25%)
		leucine-rich repeat	84..103	CDD:275380	3/18 (17%)
		leucine-rich repeat	104..128	CDD:275380	5/23 (22%)
		leucine-rich repeat	129..152	CDD:275380	8/22 (36%)
		leucine-rich repeat	153..177	CDD:275380	7/23 (30%)
		leucine-rich repeat	178..201	CDD:275380	8/82 (10%)
		leucine-rich repeat	202..226	CDD:275380	9/23 (39%)
		leucine-rich repeat	227..250	CDD:275380	9/22 (41%)
		leucine-rich repeat	251..279	CDD:275380	8/27 (30%)
		leucine-rich repeat	280..326	CDD:275380	15/45 (33%)
		leucine-rich repeat	327..348	CDD:275380	4/20 (20%)
		leucine-rich repeat	352..375	CDD:275380	7/22 (32%)
		PPP1R42	355..564	CDD:455733	52/211 (25%)
		leucine-rich repeat	376..401	CDD:275380	4/24 (17%)
		leucine-rich repeat	426..450	CDD:275378	5/26 (19%)
		leucine-rich repeat	451..474	CDD:275380	4/22 (18%)
		LRR_8	473..559	CDD:404697	23/85 (27%)
		leucine-rich repeat	475..524	CDD:275380	13/48 (27%)
		leucine-rich repeat	500..519	CDD:275380	6/18 (33%)
		leucine-rich repeat	525..548	CDD:275380	6/22 (27%)
		LRR	<540..>834	CDD:443914	86/301 (29%)
		leucine-rich repeat	549..574	CDD:275380	9/24 (38%)
		leucine-rich repeat	575..598	CDD:275380	10/22 (45%)
		leucine-rich repeat	599..622	CDD:275380	5/22 (23%)
		leucine-rich repeat	623..646	CDD:275380	7/22 (32%)
		leucine-rich repeat	647..730	CDD:275380	19/90 (21%)
		leucine-rich repeat	648..673	CDD:275380	6/24 (25%)
		leucine-rich repeat	674..705	CDD:275380	5/37 (14%)
		LRR	<730..1081	CDD:443914	89/352 (25%)
		leucine-rich repeat	731..754	CDD:275380	6/22 (27%)
		leucine-rich repeat	755..778	CDD:275380	7/22 (32%)
		leucine-rich repeat	779..802	CDD:275380	6/22 (27%)
		leucine-rich repeat	803..823	CDD:275380	7/19 (37%)
		leucine-rich repeat	852..876	CDD:275380	6/24 (25%)
		leucine-rich repeat	877..900	CDD:275380	7/22 (32%)
		leucine-rich repeat	901..925	CDD:275380	8/23 (35%)
		leucine-rich repeat	926..946	CDD:275380	5/19 (26%)
		leucine-rich repeat	947..970	CDD:275380	4/22 (18%)
		leucine-rich repeat	971..993	CDD:275380	6/22 (27%)
		leucine-rich repeat	994..1014	CDD:275380	8/19 (42%)
		leucine-rich repeat	1019..1042	CDD:275380	4/22 (18%)
LOC1279967	XP_061513522.1	None