Protein Alignment chp and lrrc53

DIOPT Version :10

• Sequence 1: NP_001263137.1
• Gene: chp / 43690
• FlyBaseID: FBgn0267435
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_021322571.1
• Gene: lrrc53 / 101882576
• ZFINID: ZDB-GENE-131121-432
• Length: 838
• Species: Danio rerio
• Alignment Length: 568
• Identity: 121/568 - (21%)
• Similarity: 191/568 - (33%)
• Gaps: 194/568 - (34%)

  Fly   413 DPTNLQTLRKMRNMRSLSISRLGSSSVGPEDFKDFGVELEDLQITRASLSGIQSHAFKHVRGLKR 477
            |.|..|.||.:       |...||:..              |.:|...:..:.|..|..:..:..
Zfish    31 DVTICQKLRSI-------IDAPGSTKA--------------LMLTDGLIDSVGSMVFSDLSNMSV 74

  Fly   478 LDFSENGISSIENDAFHEIGHSLISLKMSHGYSGSALPAEPLRHLTSLQELDFSNNHIS--SMSD 540
            |..|.|.||||..:||                          ::||.|..|...:||||  :::.
Zfish    75 LALSNNAISSITENAF--------------------------QNLTFLTTLSLDHNHISNQALNS 113

  Fly   541 TSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISLRFNHLTSISQHTFFDLEALRKLHLD 605
            ::|.:|..|..|:|.:|.::.:....||..|  .|:.:.|..|.|||::..||
Zfish   114 STFSWLHRLETLQLSNNHLKDIDGSWFQSSI--ALKTLQLDGNLLTSLNSTTF------------ 164

  Fly   606 DNKIDKIERRAFMNLDELEYLSLRGNKINNLADESFQNLPKLEILDMAFNQLPNFNFDYFDQVGT 670
                      |..:|..||.|.|..|.|..|..|||:.||.|..||::.|.|.:.. |.|..:..
Zfish   165 ----------AHADLRNLEILDLSDNLIVTLGRESFRRLPSLRRLDLSRNNLSSAP-DAFSYLSW 218

  Fly   671 LSNLNVNVSH--------------NQIRQLMYNSSWSGR-----NEHGGMYHSNIKILDLS---- 712
            ||.||::::.              |...|...|..::|:     |.......:.:::.|.:
Zfish   219 LSTLNLDLNRWSCSCELRELASFLNSFIQAPENVLYNGQKMACVNADNPSVQTVLQLTDANCVPP 283

  Fly   713 HNNISI--------IHPGYFRPAEISLTHLHLG------------YNSLMNTTR---------DV 748
            ::||::        ....|.|...|::....||            |:.|....:         :.
Zfish   284 NSNITVEVVAKRSNTSQQYIRNVAIAVVFSFLGGVGITLGIIAIAYHKLSKKFKLMQEEHGASER 348

  Fly   749 FGNMPHL-QWLDLSYNWIHELDFDAFKNTKQLQLVFFGHNYLSDIPQDIFKPVQGLRIVDFSHNH 812
            ..:.|.: ||           :|...|:|..:....:..||.|..|.|......|   .|...||
Zfish   349 ITSSPEMAQW-----------NFCEGKDTLSMSHALYNSNYKSHQPWDREDSPYG---SDELENH 399

  Fly   813 ---------------------LRGLPDNLFYNGGMEKL-DVSHNMMLKIPSSSLSSLAALTLCEL 855
                                 |:...:||..|...|.| ...||      .:...|:....:.::
Zfish   400 FTCHKCSSTALTGGKPKRETVLQKTTENLQKNHMSEHLAHRQHN------GNQQHSVLQQRIKDM 458

  Fly   856 HL-------------SNNFIS------------TIHSMDLSNKFRSLR 878
            ||             |.:|.|            .|..:.|||.|.:|:
Zfish   459 HLKRQAERDSKSHLASQDFTSQRRGGPDDISAVRIQQLALSNHFSALQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chp	NP_001263137.1	LRR	<84..320	CDD:443914
		leucine-rich repeat	84..103	CDD:275380
		leucine-rich repeat	104..128	CDD:275380
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		PPP1R42	355..564	CDD:455733	35/152 (23%)
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378	3/23 (13%)
		leucine-rich repeat	451..474	CDD:275380	4/22 (18%)
		LRR_8	473..559	CDD:404697	23/87 (26%)
		leucine-rich repeat	475..524	CDD:275380	10/48 (21%)
		leucine-rich repeat	500..519	CDD:275380	0/18 (0%)
		leucine-rich repeat	525..548	CDD:275380	8/24 (33%)
		LRR	<540..>834	CDD:443914	78/368 (21%)
		leucine-rich repeat	549..574	CDD:275380	7/24 (29%)
		leucine-rich repeat	575..598	CDD:275380	8/22 (36%)
		leucine-rich repeat	599..622	CDD:275380	2/22 (9%)
		leucine-rich repeat	623..646	CDD:275380	11/22 (50%)
		leucine-rich repeat	647..730	CDD:275380	21/113 (19%)
		leucine-rich repeat	648..673	CDD:275380	7/24 (29%)
		leucine-rich repeat	674..705	CDD:275380	7/49 (14%)
		LRR	<730..1081	CDD:443914	39/218 (18%)
		leucine-rich repeat	731..754	CDD:275380	4/43 (9%)
		leucine-rich repeat	755..778	CDD:275380	5/23 (22%)
		leucine-rich repeat	779..802	CDD:275380	5/22 (23%)
		leucine-rich repeat	803..823	CDD:275380	6/40 (15%)
		leucine-rich repeat	852..876	CDD:275380	10/48 (21%)
		leucine-rich repeat	877..900	CDD:275380	1/2 (50%)
		leucine-rich repeat	901..925	CDD:275380
		leucine-rich repeat	926..946	CDD:275380
		leucine-rich repeat	947..970	CDD:275380
		leucine-rich repeat	971..993	CDD:275380
		leucine-rich repeat	994..1014	CDD:275380
		leucine-rich repeat	1019..1042	CDD:275380
lrrc53	XP_021322571.1	LRR	38..>228	CDD:443914	68/261 (26%)
		leucine-rich repeat	51..71	CDD:275380	4/19 (21%)
		leucine-rich repeat	72..95	CDD:275380	10/48 (21%)
		leucine-rich repeat	96..121	CDD:275380	8/24 (33%)
		leucine-rich repeat	122..145	CDD:275380	7/24 (29%)
		leucine-rich repeat	146..171	CDD:275380	10/46 (22%)
		leucine-rich repeat	172..195	CDD:275380	11/22 (50%)
		leucine-rich repeat	196..218	CDD:275380	7/22 (32%)
		Atrophin-1	622..>785	CDD:460830