DRSC/TRiP Functional Genomics Resources

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Protein Alignment chp and igfals

DIOPT Version :9

Sequence 1:NP_001263137.1 Gene:chp / 43690 FlyBaseID:FBgn0267435 Length:1338 Species:Drosophila melanogaster
Sequence 2:XP_002940278.2 Gene:igfals / 100489984 XenbaseID:XB-GENE-1008441 Length:601 Species:Xenopus tropicalis


Alignment Length:658 Identity:162/658 - (24%)
Similarity:256/658 - (38%) Gaps:156/658 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 IMIWMSLARASMFDREMEETHYPPCTYNVMCTCSKSSTDLGIVHCKN-----VPFPALPRMVNQS 79
            :::|..|...|: :.|.......||.  ..|.||...::...|.|.:     ||.|..|...:  
 Frog    12 VLVWNILVCGSL-EAEPRSPEPAPCP--PPCVCSYDYSEEYSVFCSSRNLTRVPEPPPPAARS-- 71

  Fly    80 KVFMLHMENTGLREIEPYFLQSTGMYR-------LKISGNHLTEIPDDAFTGLERSLWELILPQN 137
                |.::...|..::      .|.:|       |.:..:.:..:...|..|| ::|..|.|.:|
 Frog    72 ----LWLDGNNLTTVQ------AGAFRNLSHLDFLNLQSSQVASLEQQALHGL-KALAHLHLERN 125

  Fly   138 DLVEIPSKSLRHLQKLRHLDLGYNHITHIQHDSFRGLEDSLQTLILRENCISQLMSHSFSGLLIL 202
            .:..:...:..|.|.|..|.|..|.:|.|:...|.|| .:|..|.|..|.:..|....|..||.|
 Frog   126 MIKSLAPSTFTHTQNLVSLTLNNNFLTKIEDGLFSGL-SNLWYLNLGWNLLVVLPDMVFHDLLNL 189

  Fly   203 ETLDLSGNNLFEIDPNVFVDGMPRLTRLLLTDNILSEIPYDALGPLKSLRTLDISHNVIWSLSGN 267
            ..|.|:||.|..:.|::|:                      :||.||.|           .||||
 Frog   190 RELVLAGNRLVYLQPSLFL----------------------SLGELKEL-----------DLSGN 221

  Fly   268 ETYEIKAST---KLNLDNLHLEYNHIEVLPPNSFKYFDTVNRTFFDGNPIHTLREDAFKPARIRE 329
            ....|||:.   :.....|:|.:|||..:.|.:|.....:.......|.:..|.||.|       
 Frog   222 SLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHNRLTALYEDTF------- 279

  Fly   330 IYMRYCGLTNISPVAFDSLVNSLQILDLSGNNLTKLHHKLFNNFDVLRVISMRDNKIKIQKPTET 394
                 .||.            ||.:|.||.|:||.|..::|.:...|..:::..|||||.. ..|
 Frog   280 -----FGLP------------SLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKIKILL-ERT 326

  Fly   395 FNAVHYTLLKLD-LSGDRNDPTNLQTLRK-----MRNMRSLSISRLGSSSVGPEDFKDFGVELED 453
            |..    |.:|: ||.:.|   |:|.:|.     :.|:..:::|.....|:....||..| :|..
 Frog   327 FEG----LAQLELLSLNHN---NVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLG-KLHS 383

  Fly   454 LQITRASLSGIQSHAFKHVRGLKRLDFSENGISSIENDAFHEIGHSLISLKMSHGYSGSALPAEP 518
            |.:..:.||.|:...|..:..::||....|.|.:||:.:|.::          ||          
 Frog   384 LHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIEDHSFTDL----------HG---------- 428

  Fly   519 LRHLTSLQELDFSNNHISSMSDTSFHFLKNLRLLELHDNRIEQVLKGTFQGDIHSKLEEISLRFN 583
                  |.|||..:|.::.::..||..||||..|.|..|:|                        
 Frog   429 ------LLELDLRSNKLTHLTTRSFTGLKNLSYLLLSSNQI------------------------ 463

  Fly   584 HLTSISQHTFFDLEALRKLHLDDNKIDKIERRAFMNLDELEYLSLRGNKINNLADESFQNLPKLE 648
              .:||...|..::.|:.|.|.||::..:....|:.|..|.||||:.|.:..::.......|.::
 Frog   464 --LTISPEVFSPVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKNNCLKTISVNFLIPPPTMQ 526

  Fly   649 ILDMAFNQ 656
            .|.:..||
 Frog   527 QLWLNGNQ 534

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chpNP_001263137.1 leucine-rich repeat 84..103 CDD:275380 2/18 (11%)
LRR_8 102..163 CDD:290566 16/67 (24%)
leucine-rich repeat 104..128 CDD:275380 5/30 (17%)
LRR_RI <128..261 CDD:238064 36/132 (27%)
leucine-rich repeat 129..152 CDD:275380 5/22 (23%)
LRR_8 152..212 CDD:290566 22/59 (37%)
leucine-rich repeat 153..177 CDD:275380 9/23 (39%)
leucine-rich repeat 178..201 CDD:275380 7/22 (32%)
LRR_8 202..261 CDD:290566 13/58 (22%)
leucine-rich repeat 202..226 CDD:275380 8/23 (35%)
leucine-rich repeat 227..250 CDD:275380 3/22 (14%)
leucine-rich repeat 251..279 CDD:275380 8/30 (27%)
leucine-rich repeat 280..326 CDD:275380 12/45 (27%)
LRR_8 326..386 CDD:290566 14/59 (24%)
leucine-rich repeat 327..348 CDD:275380 2/20 (10%)
leucine-rich repeat 352..375 CDD:275380 9/22 (41%)
leucine-rich repeat 376..401 CDD:275380 8/24 (33%)
leucine-rich repeat 426..450 CDD:275378 5/23 (22%)
LRR_RI <448..651 CDD:238064 48/202 (24%)
leucine-rich repeat 451..474 CDD:275380 6/22 (27%)
LRR_8 473..559 CDD:290566 23/85 (27%)
leucine-rich repeat 475..524 CDD:275380 9/48 (19%)
leucine-rich repeat 500..519 CDD:275380 2/18 (11%)
leucine-rich repeat 525..548 CDD:275380 8/22 (36%)
leucine-rich repeat 549..574 CDD:275380 5/24 (21%)
LRR_8 573..633 CDD:290566 16/59 (27%)
leucine-rich repeat 575..598 CDD:275380 3/22 (14%)
leucine-rich repeat 599..622 CDD:275380 7/22 (32%)
LRR_8 622..683 CDD:290566 10/35 (29%)
leucine-rich repeat 623..646 CDD:275380 6/22 (27%)
leucine-rich repeat 647..730 CDD:275380 3/10 (30%)
leucine-rich repeat 648..673 CDD:275380 3/9 (33%)
leucine-rich repeat 674..705 CDD:275380
LRR_8 704..763 CDD:290566
leucine-rich repeat 731..754 CDD:275380
LRR_8 753..813 CDD:290566
leucine-rich repeat 755..778 CDD:275380
leucine-rich repeat 779..802 CDD:275380
leucine-rich repeat 803..823 CDD:275380
leucine-rich repeat 852..876 CDD:275380
LRR_8 854..910 CDD:290566
LRR_RI <877..>1006 CDD:238064
leucine-rich repeat 877..900 CDD:275380
leucine-rich repeat 901..925 CDD:275380
leucine-rich repeat 926..946 CDD:275380
LRR_8 947..1004 CDD:290566
leucine-rich repeat 947..970 CDD:275380
leucine-rich repeat 971..993 CDD:275380
LRR_8 992..1049 CDD:290566
leucine-rich repeat 994..1014 CDD:275380
leucine-rich repeat 1019..1042 CDD:275380
igfalsXP_002940278.2 leucine-rich repeat 69..92 CDD:275380 4/34 (12%)
PLN00113 71..>534 CDD:215061 145/594 (24%)
leucine-rich repeat 93..116 CDD:275380 4/23 (17%)
leucine-rich repeat 117..140 CDD:275380 5/22 (23%)
leucine-rich repeat 141..164 CDD:275380 9/23 (39%)
leucine-rich repeat 165..188 CDD:275380 7/22 (32%)
leucine-rich repeat 189..212 CDD:275380 9/44 (20%)
leucine-rich repeat 213..236 CDD:275380 10/33 (30%)
leucine-rich repeat 237..260 CDD:275380 7/22 (32%)
leucine-rich repeat 261..284 CDD:275380 7/46 (15%)
leucine-rich repeat 285..308 CDD:275380 9/22 (41%)
leucine-rich repeat 309..332 CDD:275380 9/27 (33%)
leucine-rich repeat 333..354 CDD:275380 7/23 (30%)
leucine-rich repeat 357..380 CDD:275380 5/23 (22%)
leucine-rich repeat 381..404 CDD:275380 6/22 (27%)
leucine-rich repeat 405..428 CDD:275380 7/32 (22%)
leucine-rich repeat 429..450 CDD:275380 7/20 (35%)
leucine-rich repeat 453..472 CDD:275380 7/44 (16%)
leucine-rich repeat 477..500 CDD:275380 7/22 (32%)
leucine-rich repeat 525..537 CDD:275378 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D299282at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm14081
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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