DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mesh and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_001163782.1	Gene:	mesh / 43688	FlyBaseID:	FBgn0051004	Length:	1454	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	274	Identity:	60/274 - (21%)
Similarity:	105/274 - (38%)	Gaps:	81/274 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 FYGFRFNYTRLSLNGYLEFSDP---------PEYLTYPLVFPIKDWPAKRDPSFMGIFFSKCRVG 257
            ::|..::...::.||.|.|..|         |.|.|..::.|:  |
Zfish   100 YFGNTYDTIFVNNNGDLTFDKPLHQYNPDNFPAYSTRDIIAPL--W------------------- 143

  Fly   258 RIYPSDIDQRTPGV--YFRVER-DLMGRTDRFGVEVRERTMWDIRQGVVGADTFIPKHVVIATWK 319
                :||:....|.  |.:|.. |::.|..:           ||.:.....: |....|.||||.
Zfish   144 ----TDINNGMEGTISYRQVTNGDILNRASK-----------DINRYFPNLN-FSASWVFIATWD 192

  Fly   320 NVSFAGGIDNSLYTTNTFQMVLATDEVYTYIIFNYAVLNWLSHTEAGGDTTKGEGGVPAYVGFNA 384
            .|.:.|..::.    :|||:||.:|:..::.:.:|..:.:....|:|.||    .|...:.....
Zfish   193 KVPYYGYRESE----STFQVVLVSDKKRSFTLMHYDYITYTQSAESGYDT----NGSTVFYSIPV 249

  Fly   385 GNGTQAYEYNPYSQNMVIRDLANRGWANGFPGRHIFRVDEQILI-GSC----NKDID---AALLP 441
            .:.|..    ||:.|:.::            ||.:||||....: |||    ::.:|   ||:..
Zfish   250 SDVTNL----PYTSNVNVK------------GRWVFRVDNSSEVKGSCINTNSQALDSPSAAVCG 298

  Fly   442 LTFAPESGNMLGGQ 455
            :.....|...:|||
Zfish   299 IIPVNSSNGTVGGQ 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mesh	NP_001163782.1	NIDO	259..419	CDD:214712	35/162 (22%)
		AMOP	660..805	CDD:281737
		VWD	811..999	CDD:214566
		CCP	1121..1171	CDD:214478
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035	39/191 (20%)
		Tryp_SPc	309..537	CDD:238113	3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4291
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900