Protein Alignment mesh and LOC100485083

DIOPT Version :10

• Sequence 1: NP_001163782.1
• Gene: mesh / 43688
• FlyBaseID: FBgn0051004
• Length: 1454
• Species: Drosophila melanogaster
• Sequence 2: XP_031761683.1
• Gene: LOC100485083 / 100485083
• XenbaseID: XB-GENE-29077611
• Length: 1015
• Species: Xenopus tropicalis
• Alignment Length: 594
• Identity: 141/594 - (23%)
• Similarity: 216/594 - (36%)
• Gaps: 150/594 - (25%)

  Fly    67 EADNPKTKPLALQKPTLIPVVHVSSRGTDDILTVAGLKPEKMFGALIMPNDYLGELYDVDNSGYN 131
            |:..|:|             |...|..|.:..|.| .:||..|    ..:|...|:|
 Frog   355 ESTTPET-------------VFTESGSTTETQTDA-TEPETTF----TESDTTTEMY-------- 393

  Fly   132 WDPNNNVAPPTTYS---------TAAGGYTITAARLAELRSNFMYWYFDKDMYGGRGDY---QFD 184
               ...:.|.|||:         ||......|..|....|:..:|      .||...|:   :.|
 Frog   394 ---TGTIIPETTYTPSYFTTYSQTAQSTIQQTTERQVIYRNALLY------PYGPGLDFVTIKSD 449

  Fly   185 IHAS-MTQLHKNLNFQLPFYGFRFNYTRLSLNGYLEFSDPPEYLTYPLVFPIKDWPAKRDPSFMG 248
            ..|| ..||..|::    .:|..|:...:..||.:.|:           .||..:.....|:...
 Frog   450 DGASEAIQLSMNIS----IFGKSFSSLYIDTNGLISFN-----------LPIYTYTPAHLPAIGN 499

  Fly   249 IFFSK--CRVGRIYPSDIDQRTPGVYFR--VERDLMGRTDRFGVEVRERTMWDIRQGVVGADTFI 309
            :|.:.  ..|..::.|||       |:|  .|..|:.:...           |||:.....: |.
 Frog   500 MFIAPFWADVYNVFQSDI-------YYRESTEASLLSQATS-----------DIRRYFHNMN-FS 545

  Fly   310 PKHVVIATWKNVSFAGGIDNSLYTTNTFQMVLATDEVYTYIIFNYAVLNWLSHTEAGGDTTKGEG 374
            .|.|.:.||..|.:.|   :|....||||.|:.||...||::|||..:.|.:.|.:||.:..|.|
 Frog   546 AKWVFVVTWHKVPYFG---SSSSKVNTFQAVITTDGNLTYVMFNYGDIEWTTGTASGGSSVSGLG 607

  Fly   375 GVPAYVGFNAGNGTQAYEYNPYSQNMVIRDLANRGWAN-GFPGRHIFRVDEQILIGSCNKDIDAA 438
            |:||..|.|:||.|..||. |.|.:..|.:||:.  :| ||.||..|:|::  ||..........
 Frog   608 GIPALAGINSGNFTGFYEI-PGSMSASIINLAST--SNVGFSGRWAFQVND--LIPDVLNGKTTL 667

  Fly   439 LLPLTF------------APESGNMLGGQVVNITGPCFDPAIRVTCHFDTESVLGTYVDRNRVIC 491
            |.|..:            ||.|.|:  ..|:.|.|..:.               ..||:.|
 Frog   668 LYPYGYALDTVTEGLDDHAPYSVNL--STVIPIFGTNYS---------------SLYVNYN---- 711

  Fly   492 VQPYLKAEGYIRFQISVGTQ--------RFKWRGKYFVETPAAATEKIFF-TTDDVHKKNPAEIR 547
                    |.|.|...||.|        ...:...::....:.....||| .:.|....:.|...
 Frog   712 --------GLISFSAPVGPQTPQNLPLSNIAFLAPFWTHVSSYVGGYIFFRLSRDAELLSRATSD 768

  Fly   548 ITWNQYNLTSNANANVMISLWGYRETKIEPQLEYIDVIEASYSNSGSYVITPSNYINRNNINRDM 612
            |: :.:|:|..:...|::..|    ::.|.....::..:...|:.|:......||.:.|......
 Frog   769 IS-SYFNITYFSAQWVLVVTW----SRTENITNKVNTFQTILSSDGNVTYLLFNYADINWTTGTA 828

  Fly   613 QFGFLQINL 621
            ..|..||.|
 Frog   829 AGGASQIGL 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mesh	NP_001163782.1	NIDO	259..419	CDD:214712	56/162 (35%)
		TIG	446..511	CDD:460355	14/64 (22%)
		AMOP	660..803	CDD:461048
		VWD	811..999	CDD:214566
		CCP	1121..1171	CDD:214478
LOC100485083	XP_031761683.1	NIDO	218..352	CDD:470642
		NIDO	504..653	CDD:214712	58/173 (34%)
		NIDO	738..889	CDD:470642	20/105 (19%)