Protein Alignment stops and ASB17

DIOPT Version :9

• Sequence 1: NP_733416.2
• Gene: stops / 43683
• FlyBaseID: FBgn0086704
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_543144.1
• Gene: ASB17 / 127247
• HGNCID: 19769
• Length: 295
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 61/286 - (21%)
• Similarity: 112/286 - (39%)
• Gaps: 107/286 - (37%)

  Fly   149 QVCLMGKYHNILYIGLRTCWDWGVRDSEVVVKLLVAIYECEKTYERIFLGALFGPHAPHFIAGWR 213
            ::|:    :.|||      |.:..:.:...|:||:     :||.:.:
Human    91 EICV----NTILY------WVFARKGNPDFVELLL-----KKTKDYV------------------ 122

  Fly   214 SDFQDQHENVRAMVYFLKHATREQLTLPVWIPRFEQERQLRFIDVPIESCGKSSPLRIALQANAP 278
               ||:..|: |:::        :...||:.|.            |:...   :||....|....
Human   123 ---QDRSCNL-ALIW--------RTFTPVYCPS------------PLSGI---TPLFYVAQTRQS 160

  Fly   279 ELLLILLRYGAAPQ---PPDGGASVII------ALLDK----LIEDGRNYSFELVMCLKILLRNV 330
            .:..|||:||...:   |.:...::::      .::|:    :.||.:..   ||:|.::|  :|
Human   161 NIFKILLQYGILEREKNPINIVLTIVLYPSRVRVMVDRELADIHEDAKTC---LVLCSRVL--SV 220

  Fly   331 VMIEMPFKPLLYAARREM---FFDRYGRLLMDKIIGKEQVYGVPSLR--------HLCRCCIRDV 384
            :.:: ..|..|...|..:   :||.                 :||.|        ||||..||:.
Human   221 ISVK-EIKTQLSLGRHPIISNWFDY-----------------IPSTRYKDPCELLHLCRLTIRNQ 267

  Fly   385 MRMHNQLPSGIDTLRLPKRLQRYIDL 410
            :..:|.||.||.:|.:|.|||.|::|
Human   268 LLTNNMLPDGIFSLLIPARLQNYLNL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stops	NP_733416.2	SOCS_box	370..408	CDD:284857	19/45 (42%)
ASB17	NP_543144.1	ANK	95..177	CDD:321973	25/137 (18%)
		ANK	146..176		8/32 (25%)
		SOCS_ASB_like	251..294	CDD:239686	18/43 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141114
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR20966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.990