DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gycbeta100B and Adcy7

DIOPT Version :9

Sequence 1:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_445848.1	Gene:	Adcy7 / 84420	RGDID:	619966	Length:	1100	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	84/267 - (31%)
Similarity:	136/267 - (50%)	Gaps:	45/267 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   455 LHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANEL--- 516
            |.||:|||.:                 .|.|..|..|.|..||::.:.||.||||..::..:
  Rat   203 LQDASRDLFI-----------------YTVKCIQIRRKLRVEKRQQENLLLSVLPAHISMGMKLA 250

  Fly   517 ----------RHQRP------VPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYT 565
                      ||..|      :..||:.:|:::::.||||.: .|::..|   .::|.:||||:.
  Rat   251 IIERLKEGGDRHYTPDNNFHSLYVKRHQNVSILYADIVGFTR-LASDCSP---KELVVVLNELFG 311

  Fly   566 VFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGSN-PVQI 629
            .||.:  :|.| ...:::.:||.|..|||||.....||:...::.||:.:..|.|:..:. .:.:
  Rat   312 KFDQI--AKAN-ECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIKQVREATGVDISM 373

  Fly   630 TIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHL 694
            .:|||||.|:.||||.|..:|.::.:.|:|.:|.|..|||||::::|.|...|..|...:|. |.
  Rat   374 RVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLNHLDKAYEVEDG-HG 437

  Fly   695 EYRGPVI 701
            |.|.|.:
  Rat   438 EQRDPYL 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	19/60 (32%)
		CYCc	496..688	CDD:214485	68/211 (32%)
		Guanylate_cyc	522..714	CDD:278633	62/181 (34%)
Adcy7	NP_445848.1	AC_N	<21..251	CDD:318454	19/64 (30%)
		Guanylate_cyc	272..422	CDD:306677	54/156 (35%)
		DUF1053	487..593	CDD:399378
		Guanylate_cyc	891..1087	CDD:306677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810