Protein Alignment Gycbeta100B and gucy2ca

DIOPT Version :10

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_073799927.1
• Gene: gucy2ca / 572052
• ZFINID: ZDB-GENE-091118-67
• Length: 1071
• Species: Danio rerio
• Alignment Length: 841
• Identity: 209/841 - (24%)
• Similarity: 326/841 - (38%)
• Gaps: 243/841 - (28%)

  Fly    25 IKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPAD--DILELFGKTFFEFCQDS------ 81
            |||...|..:..|::..:|::....|        .:.||.  ::|.|...:|..:..:|
Zfish   254 IKKNNTVPSQVVFILIDLYNEGYRTN--------ESSPAHMRNVLVLTMHSFRNYSSNSVWRNNT 310

  Fly    82 --------GYDKILQVLGATPRDFLQNL---DALHDHLGTLYPGMRAPSFRCTEKDGELLLHYYS 135
                    ||...:.:.|...|:.||.:   ..|.|::.        |.||.....|  :..||.
Zfish   311 TALNDYVVGYHDAVVLFGNAMRNNLQRIKQQQGLSDNID--------PPFRNMSFYG--IGGYYK 365

  Fly   136 -ERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGE--------PIDEAE--KERAIARENQQLL 189
             :..|...:.:.:|....|..:......|..:.:.:        |.|.::  :::....|.|:::
Zfish   366 LDSSGDRDLNLSVVYTTGSYKYRTLFSFDTSQNRTKVKDSSPDLPWDRSQLPRDKHTGMEIQEIM 430

  Fly   190 EDAVATTTTGSATVV-------------------------LAPSSDAERN-------NNHNGSNG 222
            ...:..:.. .|||:                         :.|..|.|||       .:..|.|.
Zfish   431 MIVLGLSVV-LATVIAFILYRQNRRVRFDQKKWSHISSSLITPLDDKERNYISLTIDEDKKGDNS 494

  Fly   223 S------------------NNNGMANNGNTVNVNNNNDGQQIASETDPSIALSTCPIAQ----DS 265
            |                  |.:|           |..|.|:|  |.:..:.:....:.:    ..
Zfish   495 SLIRKGRYDKKPVILKELRNTDG-----------NFTDDQRI--ELNALLRIDYYNLTKFYGTVR 546

  Fly   266 FDCD--GDKEQKCLR-LLKNKSDDIERYDHVQFL------------------IREINVAAKSQVD 309
            |||.  |..| .|.| .|:...||...|....|:                  :...||....::.
Zfish   547 FDCGVFGVFE-FCERGSLRYVLDDKISYPDASFMDLEFRISVMYDIAKGMSYLHSSNVGVHGRLK 610

  Fly   310 AKKDEVPDDM-----EFLCEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEE--- 366
            :....|.:.|     :|.|.. ::||.......|.|:   |...|.|.|...|..|  :::|
Zfish   611 STNCVVDNRMVVKITDFGCNT-ILSPGKDLWTAPEHM---RVEGISQKGDVYSFAI--ISQEIIL 669

  Fly   367 --------NCSLIEVVEAIRPHLQLNFENILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYI 423
                    .||  ::.|                  .:|::|..:|....|.:   |..:|    :
Zfish   670 RKSPFHTSCCS--DMAE------------------KLYLVQYPRGPNVFRPD---LSFEG----V 707

  Fly   424 PETDRILFQCYPSVMNLDDLTKK----------GLYISDVPLHDAARDLVLLSEKFEAEY--KLT 476
            .||:..||....|... :|..|:          |...|:  ||:.|          .|.|  .|.
Zfish   708 GETEAELFVLIKSCWE-EDPEKRPDFKRIEGALGKIFSN--LHNQA----------NASYMDNLI 759

  Fly   477 KNLEMLTDKLQQTFRD----LESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGI 537
            :.|:|.:..|:....:    .::|:.:.|:|.:.:||..|...|:....|.|:.||.||:.||.|
Zfish   760 RRLQMYSRNLEHLVEERTALYKAERDRADQLNFMLLPGPVVRSLKETGRVEPELYDEVTIYFSDI 824

  Fly   538 VGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCED- 601
            |||...|..:|    .|::|.|||::|..||::.|   :.:||||||:||.||..|||| .|..
Zfish   825 VGFTTICHHST----PMEVVDMLNDIYKNFDSILD---HHDVYKVETIGDAYMVASGLP-RCNGN 881

  Fly   602 -HAKCMARVALDMMDMAKNVKMGS--------NPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTV 657
             ||..:..:|||:::.     ||:        .|:.|.||||||....||:||::|||||||:||
Zfish   882 RHAVDICLMALDILEF-----MGTFQLRHLPGIPLWIRIGIHSGPCAAGVVGNKMPRYCLFGDTV 941

  Fly   658 NLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFLTRAT 718
            |..||.|:||:|.||:|||.|.::|   ...|..|..|.||...:|||...|..| ||..|
Zfish   942 NTASRMESTGLPLRIHVSESTIKIL---QRTDCEFECERRGETFLKGKGKEMTYW-LTGVT 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:462233	30/158 (19%)
		HNOBA	326..516	CDD:462234	44/216 (20%)
		Guanylate_cyc	522..714	CDD:425528	90/201 (45%)
gucy2ca	XP_073799927.1	None