DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gycbeta100B and CG33958

DIOPT Version :9

Sequence 1:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster

Alignment Length:	540	Identity:	149/540 - (27%)
Similarity:	240/540 - (44%)	Gaps:	138/540 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 DGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLISPATF 333
            :|.|::..|.|         |:.:....:..:...::..|....||..||.|
  Fly   176 NGSKQRANLTL---------RFANTDHALNNMTTWSEISVPTAPDEDEDDRE------------- 218

  Fly   334 CKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVV-------EAIRPHLQ--------- 382
                   :|.:|.....:..:...||  |:..|..|:.||:       ..:..||.
  Fly   219 -------MMLNRYEFQSRLNEFRDRV--RLEPEESSITEVMNWYTSINRGLLHHLSEQIKETDNS 274

  Fly   383 ------LNFENILSHI------NTIYVLQTRQGAMSSRHEQRFLR------------------LK 417
                  :.|:|:|..|      .:..:....:|::::.:...::|                  ||
  Fly   275 GVWRYLVGFKNLLKSIECQNIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMINSTLNYAPMLK 339

  Fly   418 GQMMYIPETDRI---------LFQCYPSVMN--------------LDDL--TKKGL------YIS 451
            .....|..|.:.         |.:..|:|.|              .|||  .:|.|      |:
  Fly   340 NMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYELMNNYTDDLRILQKALRRLIKEYV- 403

  Fly   452 DVPLHDAARD-------LVLLSEKFEAEYKLTKN----LEMLTDKLQQTFRDLESEKQKTDRLLY 505
            |..|.:|.|.       ||::.........|.||    :::....|.|..::|:.||:|:|.||:
  Fly   404 DKTLVEADRKEAIGIAILVVVLIVSPVIIVLVKNAAATIQLYALNLSQKAKELKREKRKSDSLLF 468

  Fly   506 SVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDAL 570
            .:||.|||.:|:..:.||.:.|::||:.||.||||.: .||:..|   :::|..||.:|.|||..
  Fly   469 QMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTE-IAADCTP---LEVVTFLNSIYRVFDER 529

  Fly   571 TDSKRNLNVYKVETVGDKYMAVSGLP-DHCEDHAKCMARVALDMMDMAKNV----KMGSNPVQIT 630
            .:.   .:||||||:||.||..|||| .:...|...:|.:|||::| |.:|    :.|...|||.
  Fly   530 IEC---YDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLD-ASSVFRIPRAGDEFVQIR 590

  Fly   631 IGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLE 695
            .|:|:|.||.|::|.::|||||||:|||..||.|:||...:|:::||.:.    ::.|...|..|
  Fly   591 CGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHD----SLQQVGGFRTE 651

  Fly   696 YRGPVIMKGKPTPMDCWFLT 715
            :||.:.:|||.. |..::||
  Fly   652 HRGLIDVKGKGL-MSTYWLT 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	54/277 (19%)
		CYCc	496..688	CDD:214485	84/196 (43%)
		Guanylate_cyc	522..714	CDD:278633	81/196 (41%)
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	40/250 (16%)
		HNOBA	<439..479	CDD:285003	14/39 (36%)
		CYCc	459..647	CDD:214485	85/199 (43%)
		Guanylate_cyc	485..669	CDD:278633	81/196 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820