DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gycbeta100B and Ac13E

DIOPT Version :9

Sequence 1:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_001259575.1	Gene:	Ac13E / 32485	FlyBaseID:	FBgn0022710	Length:	1703	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	98/372 - (26%)
Similarity:	165/372 - (44%)	Gaps:	98/372 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   453 VPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELR 517
            |.:|....:||.:...|   .|:.:||.:.        |.||.|||..:::::||:|..||:.|.
  Fly   271 VGVHVLIMNLVRMRGTF---MKVGQNLLVR--------RQLEMEKQLKEKMIHSVMPPKVADMLL 324

  Fly   518 HQ------------------------------RPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDG 552
            ::                              ||......::|:::|:.||||.:..:..|
  Fly   325 NEGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKT---- 385

  Fly   553 AMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMA 617
            |.::|::||:|:..||.|....   ...|:.|:||.|..|||.|:...|||.|...:.|.|:|..
  Fly   386 AEQLVEILNDLFERFDDLCSLS---GCEKISTLGDCYYCVSGCPEPRADHAICCVEMGLGMIDAM 447

  Fly   618 K--------NVKMGSNPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINV 674
            :        .|||       .:|:|:|.|:.|::|.|..::.::.|.|:|.::.|::|.|.::::
  Fly   448 RCFDAQRHEGVKM-------RVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGKPEQVHI 505

  Fly   675 SEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFL-------TR-----------ATSS- 720
            |:||...|      .|:::||....|.  |..|    :|:       ||           ||.|
  Fly   506 SQETSSFL------GDAYYLEEGEEVF--GHRT----YFVVGRRRDFTRTNSLSPSMPANATGSS 558

  Fly   721 -ILGGTSSTGGSGGGGNGSLDSPLLQPATPT---AGAATPIPVVAQR 763
             :|.|......|....|.|...|.:.||:|.   :.:..|.||::.|
  Fly   559 LLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSLNPSPVLSMR 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	19/62 (31%)
		CYCc	496..688	CDD:214485	62/229 (27%)
		Guanylate_cyc	522..714	CDD:278633	57/199 (29%)
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	63/235 (27%)
		Guanylate_cyc	361..535	CDD:278633	58/199 (29%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453960
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740