Protein Alignment Gycbeta100B and Npr1

DIOPT Version :10

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_036745.1
• Gene: Npr1 / 24603
• RGDID: 3195
• Length: 1057
• Species: Rattus norvegicus
• Alignment Length: 721
• Identity: 189/721 - (26%)
• Similarity: 286/721 - (39%)
• Gaps: 227/721 - (31%)

  Fly    29 AMVSMEGQFLVRQIYDDEITY--NLIGAAVEILNIPADDILELFGKTFFEFCQDSGYDKILQVLG 91
            ::::.||||   |::.....|  ||:  ||:.:|...   :||..|..||
  Rat   538 SLLTTEGQF---QVFAKTAYYKGNLV--AVKRVNRKR---IELTRKVLFE--------------- 579

  Fly    92 ATPRDFLQNL-DALHDHLGTLYPGMRAPSFRCTEKDGELLLHYYSERPGLEHIVIGIVKAVASKL 155
                  |::: |..::|| |.:.|      .||:.....:|..|..|..|:.|           |
  Rat   580 ------LKHMRDVQNEHL-TRFVG------ACTDPPNICILTEYCPRGSLQDI-----------L 620

  Fly   156 HGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAVATTTTGSATVVLAPSSDAERNNNHNGS 220
            ....:.:|.:.|                  ..|..|.|      ...:.|           |||:
  Rat   621 ENESITLDWMFR------------------YSLTNDIV------KGMLFL-----------HNGA 650

  Fly   221 NGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIALSTCPIAQDSFDCDGDKEQ----------- 274
                   :.::||..:.|...||:.:...||..:         :||. |.:.||
  Rat   651 -------ICSHGNLKSSNCVVDGRFVLKITDYGL---------ESFR-DPEPEQGHTLFAKKLWT 698

  Fly   275 --KCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLISP------A 331
              :.||:....:...:..|...|.|....:|.:|.|            |..|...:||      .
  Rat   699 APELLRMASPPARGSQAGDVYSFGIILQEIALRSGV------------FYVEGLDLSPKEIIERV 751

  Fly   332 TFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLNFENILSHINTIY 396
            |..:..||....|.|..:.:.|:.:.|......:|.....::..|:|...:.|..|||.:
  Rat   752 TRGEQPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKENSSNILDN----- 811

  Fly   397 VLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRILFQCYPSVMNLDDLTKKGLYISDVPLHDAARD 461
                    :.||.||
  Rat   812 --------LLSRMEQ-------------------------------------------------- 818

  Fly   462 LVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKR 526
                         ...|||.|.::..|.:.:   ||:|.:.|||.:||.|||.:|:....|..:.
  Rat   819 -------------YANNLEELVEERTQAYLE---EKRKAEALLYQILPHSVAEQLKRGETVQAEA 867

  Fly   527 YDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMA 591
            :||||:.||.||||....|.:|    .|::|.:||:|||.|||:.|   |.:||||||:||.||.
  Rat   868 FDSVTIYFSDIVGFTALSAEST----PMQVVTLLNDLYTCFDAVID---NFDVYKVETIGDAYMV 925

  Fly   592 VSGLP-DHCEDHAKCMARVALDMMDMAKNVKMGSNP---VQITIGIHSGEVVTGVIGNRVPRYCL 652
            ||||| .:.:.||:.:||:||.::|..::.::...|   :::.||||:|.|..||:|.::|||||
  Rat   926 VSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCL 990

  Fly   653 FGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFLTRA 717
            ||:|||..||.|:.|...:|::|.||..:|    .:.|.|.||.||.|.||||......|.|...
  Rat   991 FGDTVNTASRMESNGEALKIHLSSETKAVL----EEFDGFELELRGDVEMKGKGKVRTYWLLGER 1051

  Fly   718 TSSILG 723
            ..|..|
  Rat  1052 GCSTRG 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:462233	30/137 (22%)
		HNOBA	326..516	CDD:462234	36/195 (18%)
		Guanylate_cyc	522..714	CDD:425528	88/195 (45%)
Npr1	NP_036745.1	PBP1_NPR_A	32..439	CDD:380608
		PK_GC-A_B	530..803	CDD:270944	73/375 (19%)
		HNOBA	<809..857	CDD:462234	21/126 (17%)
		CYCc	836..1025	CDD:214485	88/202 (44%)