Protein Alignment Gycbeta100B and gcy-20

DIOPT Version :9

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_507101.1
• Gene: gcy-20 / 184797
• WormBaseID: WBGene00001545
• Length: 1108
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 149/599 - (24%)
• Similarity: 239/599 - (39%)
• Gaps: 181/599 - (30%)

  Fly   236 NVNNNN---------DGQQI------ASETDPSIALSTCPIAQDSF------------------- 266
            |.:|:|         ||.|:      .|....|..:|...:..|||
 Worm   592 NFDNDNLNKFIGLCLDGPQLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYFIHSS 656

  Fly   267 --DCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEV---------PDDME 320
              .|.|....:|..:     ||..:.....|.::.:    ::..:.||:::         .:|.|
 Worm   657 FLKCHGQLTSRCCLI-----DDRWQIKISGFGLKSV----RTFENPKKEDLLWASPEYLRNEDQE 712

  Fly   321 FLCEAPLISPATFC-KVFPFHLMFDRQ----------MKIVQAGKAVSRVIPRVAEE---NCSLI 371
            .|.|..:.|....| ::......||.:          .::.:.|...:|......|.   |.:|:
 Worm   713 RLPEGDIYSFGIICAEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPTRPSLDTGETVVINPALL 777

  Fly   372 EVVE---AIRPHLQLNFENILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRI--LF 431
            .:|.   ..||..:.:.|.:.||:|         |....|        |..:|     |.:  :.
 Worm   778 HLVRDCWTERPSERPSIEQVRSHLN---------GMKDGR--------KTNLM-----DHVFNML 820

  Fly   432 QCYPSVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESE 496
            :.|.|.:.                                        |.::|:.    ::|..|
 Worm   821 ETYASTLE----------------------------------------EEVSDRT----KELTEE 841

  Fly   497 KQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLN 561
            |:|:|.|||.:||:.||::|:..:.|.|:.::.||:.||.:|.|.......|    .:::|.:||
 Worm   842 KKKSDVLLYRMLPRMVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLAGKCT----PLQVVTLLN 902

  Fly   562 ELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPD-HCEDHAKCMARVALDMMDMAKNVKMGSN 625
            :|||:||.:.:..   :||||||:||.|:.|||||. :..||.:.:||::|..:...:..::...
 Worm   903 DLYTIFDGIIEQN---DVYKVETIGDGYLCVSGLPHRNGNDHIRHIARMSLGFLSSLEFFRVQHL 964

  Fly   626 P---VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAIN 687
            |   :.:.|||:.|.||.||:|..:|||||||:.||..||.|:.|.||:|:|:.|..|:|...:.
 Worm   965 PAERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGQIHVTAEANRMLTQVVG 1029

  Fly   688 QDDSFHLEYRGPVIMKGKPTPMDCWFL----------------------TRATSSIL------GG 724
               .|..|.||.||:|||......|.|                      .|:.|.||      ..
 Worm  1030 ---GFRTESRGEVIIKGKGVMETFWLLGEESGYTAPSKAAPKVIQHRQSIRSISPILEKNAEGSE 1091

  Fly   725 TSSTGGSGGGGNGS 738
            |||......|.|.|
 Worm  1092 TSSLSVDQAGDNNS 1105

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	37/208 (18%)
		CYCc	496..688	CDD:214485	78/195 (40%)
		Guanylate_cyc	522..714	CDD:278633	76/195 (39%)
gcy-20	NP_507101.1	PBP1_NPR_GC_like	22..439	CDD:107347
		ANF_receptor	44..418	CDD:279440
		PKc_like	536..801	CDD:304357	38/217 (18%)
		STYKc	562..801	CDD:214568	38/217 (18%)
		HNOBA	<818..861	CDD:285003	16/86 (19%)
		CYCc	840..1032	CDD:214485	78/201 (39%)
		Guanylate_cyc	867..1054	CDD:278633	76/196 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810