Protein Alignment Gycbeta100B and gcy-11

DIOPT Version :10

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001359843.1
• Gene: gcy-11 / 181745
• WormBaseID: WBGene00001537
• Length: 1168
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 138/477 - (28%)
• Similarity: 227/477 - (47%)
• Gaps: 90/477 - (18%)

  Fly   279 LLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLIS-----PATFCKVFP 338
            ||:|....::|...|.|:                ::|...::||.|...|.     .::.|.|..
 Worm   704 LLRNDDLRLDRMFKVSFV----------------EDVVKGLQFLHEGSKIGYHGNLKSSNCIVDA 752

  Fly   339 FHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPH--------LQLNFENILSHINTI 395
            :.     ::|:...|....||....::.:..|....|.||.:        |:|...:|.|....:
 Worm   753 YW-----RIKLSNYGMEQIRVEEPESKPDDLLWFAPEIIRRYAVKHDLSKLELAKADIYSLAIVL 812

  Fly   396 YVLQTRQGAMSS---RHEQRFLRLK---GQMMYIPETD----------RILFQCY-------PSV 437
            |.:..|||....   ..::...:||   |..:..|:..          .::.:|:       ||:
 Worm   813 YEIYGRQGPFGDDLLDSDEIIEQLKFPDGGALTRPDIHLITKAPYPLASVVEKCWVEDPASRPSI 877

  Fly   438 MNLDDLTK---KGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQK 499
            ..:.:|.|   |||      ..:.|.:::.|.:::.      .|||   |.:::....||.|:::
 Worm   878 KKVRELLKPLSKGL------KGNIADNIMNLLDRYR------NNLE---DVIKERTEQLEDERKR 927

  Fly   500 TDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELY 564
            .:.||..:|||||||.|::.:||..:.||||::.||.||||....:.:|    .:::|.|||.||
 Worm   928 NESLLLQLLPKSVANSLKNGQPVDAEFYDSVSIYFSDIVGFTALSSKST----PLQVVNMLNNLY 988

  Fly   565 TVFDALTDSKRNLNVYKVETVGDKYMAVSGLPD-HCEDHAKCMARVALDMMDMAKNVKMGSNP-- 626
            |.||.:.|   ..:.|||||:||.||.|||||: :...||..:|..:|:::|..|...:...|
 Worm   989 TNFDTIID---KFDCYKVETIGDAYMFVSGLPEVNSYLHAGEVASASLELLDSIKTFTVSHCPDE 1050

  Fly   627 -VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDD 690
             :::.||.|:|.|||||:|.|:|||||||:||.:.:..|::|.|.||.:|.:.|.|:...    .
 Worm  1051 KLRLRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYELILKC----G 1111

  Fly   691 SFHLEYRGPVIMKGKPTPMDCW 712
            .:..|.|..:::|.|...|..|
 Worm  1112 GYVTEQREKIVLKNKLEVMTYW 1133

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:462233
		HNOBA	326..516	CDD:462234	49/228 (21%)
		Guanylate_cyc	522..714	CDD:425528	77/195 (39%)
gcy-11	NP_001359843.1	Periplasmic_Binding_Protein_type1	<234..452	CDD:471960
		Protein Kinases, catalytic domain	640..890	CDD:473864	38/206 (18%)
		CYCc	923..1116	CDD:214485	83/203 (41%)