Protein Alignment Gycbeta100B and gucy1a1

DIOPT Version :9

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_002933521.3
• Gene: gucy1a1 / 100496677
• XenbaseID: XB-GENE-983418
• Length: 700
• Species: Xenopus tropicalis
• Alignment Length: 688
• Identity: 204/688 - (29%)
• Similarity: 305/688 - (44%)
• Gaps: 176/688 - (25%)

  Fly    61 IPADDILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHL------GTL--YPGMRA 117
            :|.:.:.|..|...|..|.:.. :.:|||:..|.:|||.:...   ||      .||  ..|:..
 Frog   145 VPVEHVKETLGDELFRICYEED-EHVLQVVAGTLKDFLNSFGT---HLKQSGQSRTLEECSGLEE 205

  Fly   118 PSFRCTEKDGELLLHYYSERPGLEHIVI-GIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAI 181
            .|..|.|||.:.|..||.....:..::: ||::|.|..|...|||:.::.
 Frog   206 GSILCLEKDQDYLNVYYFFPNNITPLILPGIIRAAACILFETEVEVRLIP--------------- 255

  Fly   182 ARENQQLLEDAVATTTTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQI 246
                                               |:.|:|::.........:|.|.|
 Frog   256 -----------------------------------HSCSDGNDFIKEPYLLYSVQVKN------- 278

  Fly   247 ASETDPSIALSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAK 311
               |.||::    |....|:
 Frog   279 ---TRPSLS----PSKPQSY--------------------------------------------- 291

  Fly   312 KDEVPDDMEFLCEAPLISPAT-FCKVFPFHLMFDRQMKIVQAGKAVSRV-----IPRVAEENCSL 370
                           ::.||: |||.||||.|||:.|.::|.|..|.|:     |||    ..:.
 Frog   292 ---------------VVIPASIFCKTFPFHFMFDKDMTMLQIGNGVKRLLNWRDIPR----KSTF 337

  Fly   371 IEVVEAIRPHLQLNFENILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRILFQCYP 435
            .|..|.:.|.:...|..||:.:|..:|::.:....::....:.:.|||||:|:.|:..|||...|
 Frog   338 EEYFEILSPKISCTFSGILTMLNMQFVIRVKTWDSTTDQTSKAMNLKGQMIYVFESSAILFLGSP 402

  Fly   436 SVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKT 500
            .|..|:|.|.:|||:||:|:|:|.||:||..|:..|:..|.|.|..|...|:|..:.||.||:||
 Frog   403 CVDRLEDFTGQGLYLSDIPIHNALRDVVLTGEQARAQDGLKKRLGKLKATLEQAHQALEEEKKKT 467

  Fly   501 DRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYT 565
            ..||:|:.|..||.:|.....|..|::::||::||.||||...| ::..|   |:::.||:||||
 Frog   468 VDLLFSIFPGEVAQQLWQGETVQAKKFNNVTMLFSDIVGFTAIC-SHCSP---MQVITMLSELYT 528

  Fly   566 VFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNV-KMGSNPVQI 629
            :||....   .|:||||||:||.|....||....|.||..:|.:||.||:::..| ......:::
 Frog   529 LFDFQCG---ELDVYKVETIGDAYCVAGGLHKESETHAFQVALMALKMMELSDEVMSPHGEQIKM 590

  Fly   630 TIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHL 694
            .||:|||.||.||:|.|:||||||||.|.|.::.|:..||.:||||..|||||           .
 Frog   591 RIGLHSGSVVAGVVGVRMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLL-----------K 644

  Fly   695 EYRG----PVIMKGKP------TPMDCWFLTRATSSIL 722
            :|:|    |...:..|      .|..|:||......:|
 Frog   645 DYKGFTFTPRSRQDLPPNFPSHIPGICYFLEAYNQEML 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002	33/111 (30%)
		HNOBA	326..516	CDD:285003	75/195 (38%)
		CYCc	496..688	CDD:214485	86/192 (45%)
		Guanylate_cyc	522..714	CDD:278633	81/202 (40%)
gucy1a1	XP_002933521.3	HNOBA	294..483	CDD:400168	75/192 (39%)
		Guanylate_cyc	489..676	CDD:306677	83/204 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920