DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gycbeta100B and LOC100496629

DIOPT Version :9

Sequence 1:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_031761324.1	Gene:	LOC100496629 / 100496629	-ID:	-	Length:	744	Species:	Xenopus tropicalis

Alignment Length:	554	Identity:	153/554 - (27%)
Similarity:	253/554 - (45%)	Gaps:	122/554 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 SIALSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPD 317
            ||.||||.....:.:....:...|..:|..:..|..:.......:..:|..||..:      :.:
Frog   103 SIGLSTCIKEWQNTEAAIQRLSSCTNVLAMRFIDFLQEQRKHCCLDSLNSTAKLNL------IME 161

  Fly   318 DMEFLC--------------EAPLISPATFCKVFPFHLM--FDRQMKIVQAGKAVSRVIPRVAEE 366
            .::..|              |...:|.:  ||:|...::  ||   .|.:.....|.||..:.:|
Frog   162 KVDLFCNGTQEIYNYGIRCKETTDVSYS--CKLFANKVIMRFD---NITEYNDIFSPVIAEILDE 221

  Fly   367 NCSLIEVVEAIRPHLQLNFEN-ILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQM-MYIPE---- 425
            ..:..|       .||:..|| :.:.:.::::|...:..::.|  :.||.|...: |:..:
Frog   222 FSNPDE-------DLQIPKENPVWADVLSLHLLVRAKETINKR--RNFLHLPADLKMFSYQIITM 277

  Fly   426 ------TDRILFQCYPSVMNLD-------------------------DLTKKGLYISDVPLHDAA 459
                  |...|::|:....||.                         .||....|:.:. ||..|
Frog   278 LNIAIFTSDTLYRCWKDNNNLSVYLTKFQNISLLLSFSGQTSMLCNPALTTDLNYVQEC-LHKNA 341

  Fly   460 ----RD------------------------LVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESE 496
                ||                        |||:|.|     ::|:.::.....|::...||:.|
Frog   342 NKKLRDKSKEILSTISLKISLFTVACFMYPLVLVSFK-----QMTEWIQNYAINLKERTEDLKKE 401

  Fly   497 KQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLN 561
            ::..:.||:.:||||||.:||..:.|..:.|:.||:.||.||||....|:.|    .:::|:|||
Frog   402 RRLAEDLLHQMLPKSVAKQLRKHKHVEAESYEQVTIFFSDIVGFTLISASCT----PLQVVEMLN 462

  Fly   562 ELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPD-HCEDHAKCMARVALDMMDMAKNVKMGSN 625
            .||..||:..:|   .|||||||:||.||.|||||: :...||..:|:::||::...:.|.:...
Frog   463 SLYVCFDSRIES---YNVYKVETIGDAYMVVSGLPERNYNKHADEIAKMSLDLVAAVRQVIIPHL 524

  Fly   626 P---VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAIN 687
            |   :|:..|||:|..|.||:|.::|||||||:|||..||.|:|.:|.:|::|..||::|.:
Frog   525 PNERLQLRAGIHTGPCVAGVVGYKMPRYCLFGDTVNTASRMESTSLPQKIHISSATYQVLLV--- 586

  Fly   688 QDDSFHLEYRGPVIMKGKPTPMDCWFLTRATSSI 721
             ||::.:|.||.:.:|||......|.|.....|:
Frog   587 -DDAYEIELRGEIEVKGKGKMKTYWLLGNKNYSV 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	53/256 (21%)
		CYCc	496..688	CDD:214485	84/195 (43%)
		Guanylate_cyc	522..714	CDD:278633	82/195 (42%)
LOC100496629	XP_031761324.1	HNOBA	<391..421	CDD:400168	12/29 (41%)
LOC100496629	XP_031761324.1	Guanylate_cyc	427..613	CDD:306677	82/196 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D531253at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010