Protein Alignment Gycbeta100B and gucy2d

DIOPT Version :10

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_002942678.2
• Gene: gucy2d / 100496590
• XenbaseID: XB-GENE-1014102
• Length: 1081
• Species: Xenopus tropicalis
• Alignment Length: 492
• Identity: 142/492 - (28%)
• Similarity: 217/492 - (44%)
• Gaps: 153/492 - (31%)

  Fly   363 VAEENCS-----------------------LIEVVEAIR-------PHLQLNFENILSHINTIYV 397
            |..|:||                       |:::::.::       ||.:|...|.:  ::..:|
 Frog   592 VVSEHCSRGSLEDLIQNQDMKLDWMFKSSLLLDLIKGLKFLHHRELPHGRLKSRNCV--VDGRFV 654

  Fly   398 LQTRQGAMSSRHEQRFLRLKGQMMYIPETDRILFQCYPSVMNLDDLTKKGLYISD---------- 452
            |:.....|:..::.:  ||....:. ||.   ||...|.::....|.::|.|..|
 Frog   655 LKLTDFGMNELYDAQ--RLPSTQLQ-PED---LFWTAPELLRDATLCQRGTYRGDIYSFAIIMQE 713

  Fly   453 --------------------------------VPLHDAARDLVLL-----SEKFEA--------- 471
                                            |.|..|..:.:.|     ||:.|.
 Frog   714 VIVRGPPYCMLEVTADEIIRKVLRPPPLCRPSVSLDQAPPECIQLMKLCWSEQPERRPTIDQIFD 778

  Fly   472 EYK-------------LTKNLEMLTDKLQQTFR----DLESEKQKTDRLLYSVLPKSVANELRHQ 519
            ::|             :.:.||..:..|:...|    :||.||||||:||..:||.|||..|:..
 Frog   779 QFKNINRGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEVEKQKTDKLLTQMLPPSVAEALKTG 843

  Fly   520 RPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVET 584
            .||.|:.:|.||:.||.|||| ...::.:||   :::|.:||:|||:|||:..|.   :||||||
 Frog   844 TPVEPEYFDEVTIYFSDIVGF-TTISSLSDP---IEVVDLLNDLYTLFDAIIGSH---DVYKVET 901

  Fly   585 VGDKYMAVSGLP-DHCEDHAKCMARVALDMMDMAKNVK---MGSNPVQITIGIHSGEVVTGVIGN 645
            :||.||..|||| .:...||..:|.::||::....:.|   |...||:|.||:|||..|.||:|.
 Frog   902 IGDAYMVASGLPKTNGNRHAAEIANMSLDILSSVGSFKMRHMPDVPVRIRIGLHSGPCVAGVVGL 966

  Fly   646 RVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGK----- 705
            .:|||||||:|||..||.|:||:|.|::|:..|..:|   .:..:.:..|.||...:|||
 Frog   967 TMPRYCLFGDTVNTASRMESTGLPYRVHVNLSTVTIL---HSLKEGYRFEVRGKTELKGKGVEDT 1028

  Fly   706 -------------PTPMDCWFLTRATSSILGGTSSTG 729
                         |||.|          :|.|.|:.|
 Frog  1029 YWLVGKEGFTKPLPTPPD----------VLPGGSNHG 1055

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:462233
		HNOBA	326..516	CDD:462234	50/255 (20%)
		Guanylate_cyc	522..714	CDD:425528	86/213 (40%)
gucy2d	XP_002942678.2	PBP1_sensory_GC_DEF-like	43..411	CDD:380594
		PK_GC-2D	519..786	CDD:270945	31/201 (15%)
		HNOBA	<795..840	CDD:462234	19/44 (43%)
		CYCc	820..1012	CDD:214485	91/201 (45%)