Protein Alignment Gycbeta100B and gucy1b1

DIOPT Version :9

• Sequence 1: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_004911214.1
• Gene: gucy1b1 / 100379900
• XenbaseID: XB-GENE-950986
• Length: 618
• Species: Xenopus tropicalis
• Alignment Length: 732
• Identity: 369/732 - (50%)
• Similarity: 466/732 - (63%)
• Gaps: 142/732 - (19%)

  Fly     1 MYGFVNYALELLVLKHFGEEIWEKIKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPADD 65
            ||||||:||||||::::|.|:||.|||:|.:..|||||||.||||..||:|:.||.::||:.|.|
 Frog     1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVSAATKVLNLNAGD 65

  Fly    66 ILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHLGTLYPGMRAPSFRCT--EKDGE 128
            ||::||..||.|||:||||.||:|||:..|:||||||||||||||:||||||||||||  ||...
 Frog    66 ILQMFGNMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGKG 130

  Fly   129 LLLHYYSERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAV 193
            |:|||||||.||:.|||||||.||.::||.|:::.:::::.|
 Frog   131 LILHYYSEREGLQDIVIGIVKTVAQQIHGTEIDMKVIQQRNE----------------------- 172

  Fly   194 ATTTTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIALST 258
                                                                             
 Frog   173 ----------------------------------------------------------------- 172

  Fly   259 CPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFL- 322
                    :|                      ||.||||.|        .|.::::..:|.:..
 Frog   173 --------EC----------------------DHTQFLIEE--------KDTREEDFYEDQDRFE 199

  Fly   323 ---CEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLN 384
               .:...|||.||||.||||:||||.:.:.|.|.|:.||:|::...||:|:.|...:|||:.::
 Frog   200 ENGTQESRISPYTFCKAFPFHIMFDRDLFVTQCGNAIYRVLPQLQPGNCNLLSVFSLVRPHIDIS 264

  Fly   385 FENILSHINTIYVLQTRQGAM---SSRHEQRF-------LRLKGQMMYIPETDRILFQCYPSVMN 439
            |..|||||||::||::::|.:   .|..|...       |||||||:|:||.|.|||.|.|||||
 Frog   265 FHGILSHINTVFVLRSKEGLLDVEKSESEDELTGTEISCLRLKGQMIYLPEADNILFLCSPSVMN 329

  Fly   440 LDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLL 504
            |||||::|||:||:|||||.||||||.|:|..|||||:.||:|||:||.|.|.||.||:|||.||
 Frog   330 LDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEKKKTDTLL 394

  Fly   505 YSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDA 569
            |||||.||||||||:||||.||||:||::|||||||..:|:.:...:||||||.:||::||.||.
 Frog   395 YSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNTFCSKHASGEGAMKIVNLLNDIYTRFDI 459

  Fly   570 LTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGSNPVQITIGIH 634
            ||||:.|..||||||||||||.|||:|:.|..||:.:..:|||||::|..|::....||||||||
 Frog   460 LTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHHARSICHLALDMMEIAGQVQVDGESVQITIGIH 524

  Fly   635 SGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGP 699
            :|||||||||.|:||||||||||||||||||||..|:|||||.|||.|....|.|..|||:||||
 Frog   525 TGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLQYRGP 589

  Fly   700 VIMKGKPTPMDCWFLTR 716
            |.||||..||..|||:|
 Frog   590 VSMKGKTDPMQVWFLSR 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002	108/163 (66%)
		HNOBA	326..516	CDD:285003	116/199 (58%)
		CYCc	496..688	CDD:214485	129/191 (68%)
		Guanylate_cyc	522..714	CDD:278633	124/191 (65%)
gucy1b1	XP_004911214.1	HNOB	2..166	CDD:377902	108/163 (66%)
		HNOBA	207..406	CDD:369471	116/198 (59%)
		Guanylate_cyc	412..605	CDD:306677	125/192 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	260	1.000	Domainoid score	I1929
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H664
Inparanoid	1	1.050	758	1.000	Inparanoid score	I551
OMA	1	1.010	-	-		QHG59574
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	1	1.000	-	-		FOG0002715
OrthoInspector	1	1.000	-	-		oto105270
Panther	1	1.100	-	-	LDO	PTHR45655
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5522
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080