Protein Alignment CG15556 and adgre10

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_021333746.1
• Gene: adgre10 / 569655
• ZFINID: ZDB-GENE-090313-152
• Length: 690
• Species: Danio rerio
• Alignment Length: 788
• Identity: 173/788 - (21%)
• Similarity: 297/788 - (37%)
• Gaps: 226/788 - (28%)

  Fly     7 WIAGYIILVSG---------------GTNPPLY------ALDQPNVAR------CLDYCHLKNLR 44
            |...|.:.::|               ||..||:      |::...|.|      |.|.|  .|..
Zfish    63 WSGWYRLFINGLSAHIPDTCVEVYSCGTAAPLWISGGHPAVEDGVVTRNVCSHWCGDCC--LNGS 125

  Fly    45 FLLCVDA-DGQLSHNPYKDCNRGFCKAEDFELEYETDEGKEKRINRVEKTRVGQKANLRDLCLNE 108
            |.:.|.| .|  :::.|:..:...|.|      |..|         |..|       |.:.|.:.
Zfish   126 FSIQVKACPG--NYSVYELISPLICSA------YCAD---------VHTT-------LEEACTDW 166

  Fly   109 RGIPIRRRCQIRNGNRVWQSLDHVTCRSAPELSSSINLLAVKSPPDMISQLSNLLTQTQEKLAAA 173
            ..    :.|.:    .:.:.::::|.:..| |::..|.|      ||:             |.|.
Zfish   167 TA----KDCLV----NILELIENITVQVLP-LNTVTNYL------DMV-------------LEAT 203

  Fly   174 DVFSISEIFDSLVKKPERNAAVVGDLMKICQKVMSTDNETLRVSADANATNALLSNFEDYLDELS 238
            :.|.:|...||    |...|:....:::..:|::||..:....||:.:.|   |.|.|.::..:.
Zfish   204 EKFLVSSSSDS----PAELASYGNRVLESTEKLISTLVKLTDTSANVSFT---LENVEGHVFMVG 261

  Fly   239 PT-----ILKLNTTIFANSTEFTFHPLFDMGVIVLKTSELRVFFVDPEVRNVSGIVNFSGGNMSH 298
            |.     ||:||||   ||                        |:|
Zfish   262 PNVTLNEILQLNTT---NS------------------------FMD------------------- 280

  Fly   299 FEMLHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRKGASYLVFKVYTRDSLFVETEEEIKRRPTS 363
            .:::.::.|.:|.|:    .:..|:             ||.:.:...:...| .|::...:...|
Zfish   281 IDLIGIAKNNKDTRS----AAVAFM-------------SYTIMENLLKADFF-NTQKNTNKTMMS 327

  Fly   364 NVISITIPGLNDTKLPGKLPFFLRNAKANETQFEGGCGYWNYETWLSDGISTSGGGSLEASSHPV 428
            .|||.|:|..::|.|...:.|..|:.:..:......|.|||...|:.||.|.....    |||.|
Zfish   328 TVISATLPKTSNTALTKPVNFTFRHIREFDPSGSLSCVYWNISEWIVDGCSVLNSN----SSHTV 388

  Fly   429 ILCHADHLTQFTFLLGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTL- 492
              |...||:.|..:         :.|:......|::..:.|...::||  :|.:.|:. ||...
Zfish   389 --CSCVHLSTFALI---------MQTSSSPPPSDLLDLLNLVCVIVGL--VFFSLALL-SFALCQ 439

  Fly   493 ----ASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFII 553
                .:....:|:|.:| |.....|:|:|..|  .|.:.:...|.::..::.:|.|..|.||||.
Zfish   440 WSPGVNNVARINICISL-LSAHLLLLLTQQFL--SLIRPQQVLCVVIAGLLHFLFLSAFVWMFIE 501

  Fly   554 GFLQYQRYVRVIGVNHPRHYILMS---AVAAWTLPLIPTLLVVFLEPGSYRPNNS--SMDYPILC 613
            ..|.:.....:..|:..:..:|.:   .|..:.:.||...:.:.:.|..|.....  .||
Zfish   502 AVLLFICVKNLSQVSSRKKEVLSNGFLCVIGYVVALIGVSVSIGMVPEGYGSEQCWIKMD----- 561

  Fly   614 YPSGYGLS-LGVILPIGLITVANAILVGYISWSVY--TALFK-----------RDLIFKQLGLFV 664
              .|:..| ||   |:.:|...|.||  :||.|:|  :||.|           :.::||.||.||
Zfish   562 --KGFFWSFLG---PVCVILGLNVIL--FISISIYLNSALKKLNAEVSQLKQTKVMVFKTLGQFV 619

  Fly   665 LLFFLLGITWIFGLCTYFDFGRIFAYLFCLTATLQGFVLFLYFIVFNKE----NQRAWLGLCCNS 725
                :||..||.|...:.:.  :...:|.:..:.||..:||.:.|.:.|    .::.:..||| .
Zfish   620 ----ILGCPWILGFFAHVNM--VVEIVFIIINSQQGTFIFLIYCVLSTEIRQQYKKIFTCLCC-G 677

  Fly   726 SKKRNQQT 733
            .|..|..|
Zfish   678 CKTNNVNT 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	60/245 (24%)
adgre10	XP_021333746.1	GPS	360..406	CDD:197639	17/60 (28%)
		7tm_GPCRs	413..672	CDD:333717	68/282 (24%)
		TM helix 1	413..437	CDD:320095	7/26 (27%)
		TM helix 2	446..467	CDD:320095	6/21 (29%)
		TM helix 3	481..503	CDD:320095	7/21 (33%)
		TM helix 4	527..543	CDD:320095	3/15 (20%)
		TM helix 5	561..584	CDD:320095	10/34 (29%)
		TM helix 6	608..631	CDD:320095	11/26 (42%)
		TM helix 7	635..660	CDD:320095	6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810