DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15556 and adgrg11

DIOPT Version :9

Sequence 1:	NP_001247379.1	Gene:	CG15556 / 43681	FlyBaseID:	FBgn0039821	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	XP_017208200.1	Gene:	adgrg11 / 563883	ZFINID:	ZDB-GENE-041210-320	Length:	793	Species:	Danio rerio

Alignment Length:	572	Identity:	124/572 - (21%)
Similarity:	219/572 - (38%)	Gaps:	169/572 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 KICQKVMSTDNETLRVSADANATNALLSNFEDYLDELSPTILKLNTTIFANSTEFTFHPLFDMGV 265
            :|.:|....|.:|:   .||.|..:.:.:....|..:.      |.|:.:.|          ||.
Zfish   298 EITEKFNQNDTKTV---IDAGAAASAMKDLSSMLSYMG------NLTVASVS----------MGS 343

  Fly   266 I--VLKTSELRVFFVDPEVRNVSGIVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKLW 328
            :  :||..:     .:.||...:.|.:.:.|       :.|.|   |...:||..:|:.:|::..
Zfish   344 VKGILKKIQ-----SESEVTETAFIYSPATG-------VRLID---DPTVLKNYPNALIVPKEAA 393

  Fly   329 TQ-LKRKGASYL-VFK------------VYTRDSLFVETEEEIKRRPTSNVISITIPGLNDTKLP 379
            .| |.:...::| ||:            |...:...:|...:||.  .||.|:::.
Zfish   394 QQALNQSSNAFLGVFRFPNMSKDANNSDVLNNEVYAIEMGTKIKN--LSNTINLSF--------- 447

  Fly   380 GKLPFFLRNAKANETQFEGG---CGYW----NYETWLSDGISTSGGGSLEASSHPVILCHADHLT 437
                        |.:|...|   |..|    :...|.::|..|...||       .|.|..:|||
Zfish   448 ------------NMSQSTSGTPTCYSWDGNGSKPDWTTEGCRTVVNGS-------GITCKCEHLT 493

  Fly   438 QFTFLLGVSKMQAGLDTNEDD-HSLDVITNVGLTLSL----LGLLMIFITAAVFKSFRTLASTKI 497
            .|..|:.    ...:...|.| .:|..||.:|..||:    :||.|.|:    .:..:...|..:
Zfish   494 FFAVLMA----PPDITLRESDLTALTYITYIGCGLSMFFLGVGLFMHFL----MRKAKATNSVHV 550

  Fly   498 LLNLCAALGLQLLFFL-----ILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGF-- 555
            |:||..||.:..:.||     :.:|:.:|          |.::.|.:.|.||..|:|..:...
Zfish   551 LINLFLALFMLNVAFLTNEYVVQAQNSIL----------CRVMAAFLHYCLLSSFTWFAVEALHL 605

  Fly   556 -LQYQRYVRVIGVNHPRHYILMSAVAAWTLPLIPTLLVVFLEPGSYRPNN--------------- 604
             ||..:...:      :||:|...||.|..|..  ::.|....|.|..:|
Zfish   606 CLQMTKTATL------KHYLLKITVAGWAPPAF--VVSVIFSLGKYGEDNIMTESRNVTMCWIVD 662

  Fly   605 SSMDYPI----LCYPSGYGLSLGVILPIGLITVANAILVGYIS------WSVYTALFKRDLIFKQ 659
            |::.|.:    .|:.  :..:||..:          ::|.::|      ||....:.:.......
Zfish   663 STVHYVVNIGYYCFV--FTFTLGTFI----------VVVRWLSMLRMSKWSKDGKVKRSGTATSD 715

  Fly   660 LGLFVLLFFLLGITWIFGLCTYFDFGRI---FAYLFCLTATLQGFVLFLYFI 708
            :...:.|..|||:||  |: ::|.:|.:   ..|:|.:..:||||.||:|::
Zfish   716 ISTMLGLCCLLGLTW--GI-SFFSYGALRMPSYYIFTILNSLQGFFLFVYYL 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	54/257 (21%)
adgrg11	XP_017208200.1	GPS	457..498	CDD:280071	13/47 (28%)
adgrg11	XP_017208200.1	7tm_4	511..759	CDD:304433	64/284 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5962
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12011
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7093
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.000