Protein Alignment CG15556 and Adgre4

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_631877.2
• Gene: Adgre4 / 52614
• MGIID: 1196464
• Length: 689
• Species: Mus musculus
• Alignment Length: 696
• Identity: 140/696 - (20%)
• Similarity: 258/696 - (37%)
• Gaps: 210/696 - (30%)

  Fly   175 VFSISEIFDSLVKKPE--RNAAVVGDLMKICQKVMSTDNETLRV------SADANATNALLSNFE 231
            ::||.::.:.....|:  .||:.......:|::...|.:|..|:      ..|.|  ..||.  |
Mouse    25 IWSILQMMNISASCPQCNENASCFNSTHCVCKEGFWTGSENRRIIEPHEKCQDIN--ECLLK--E 85

  Fly   232 DYLDELSPTILKLNTTIFANSTEFTFHPLFDMGVIVLKTSELRVFFVDPEVRNVSGIVNF----- 291
            ....::|....|:.|.|.:...::   |||:.                     |:||:|.
Mouse    86 LVCKDVSYCRNKIGTYICSCVVKY---PLFNW---------------------VAGIINIDHPDC 126

  Fly   292 ------SGGNMSH-FEMLHLSDNEEDI-----RAMKNLESAVF-----IPEK-------LWTQLK 332
                  :.|:.:| ..:|....::|::     :.::.:|..:.     ||:|       :..:.|
Mouse   127 YVNKSKNTGSKTHTLGVLSEFKSKEEVAKGATKLLRKVEHHILNENSDIPKKDENPLLDIVYETK 191

  Fly   333 R---------------------------KGASYLVFKVYTR-----DSLFVETEEEIKR-RPTSN 364
            |                           .|.:.:.|..|..     :..|...||..:. ...|:
Mouse   192 RCKTMTLLEAGNNTMKVDCTSGFKEHNSGGETAVAFIAYKSLGNLLNGSFFSNEEGFQEVTLNSH 256

  Fly   365 VISITI-----PGLNDTKLPGKLPFFLRNAKANETQFEGGCGYWNYETWLSDGISTSGGGSLEAS 424
            ::|..|     |.|::..|     ..|:|.:..:::.|..|.:|       :|....|..|.:..
Mouse   257 IVSGAIRSEVKPVLSEPVL-----LTLQNIQPIDSRAEHLCVHW-------EGSEEGGSWSTKGC 309

  Fly   425 SH-----PVILCHADHLTQFTFLLGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAA 484
            ||     ...:|...||:.|..|:.:...:.|:.:     :|.|||.|||:||   ||.:|:.|.
Mouse   310 SHVYTNNSYTICKCFHLSSFAVLMALPHEEDGVLS-----ALSVITYVGLSLS---LLCLFLAAI 366

  Fly   485 VFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSESE-RCTLVGAVMQYLLLVVFS 548
            .|...|.:.:|...|:      |||...|.|:....|..:.:::.: .|:::..::.||.|..|.
Mouse   367 TFLLCRPIQNTSTTLH------LQLSICLFLADLLFLTGINRTKPKVLCSIIAGMLHYLYLASFM 425

  Fly   549 WMFIIG---FLQY---------------QRYVRVIGVNHPRHYILMSAVAAWTLPLIPTLLVVFL 595
            |||:.|   ||..               :|::..:|...|...:.:||:|...
Mouse   426 WMFLEGLHLFLTVSNLKVANYSNSGRFKKRFMYPVGYGLPAFIVAVSAIAGHK------------ 478

  Fly   596 EPGSYRPNNSSMDYPILCYPSGY-GLSLGVILPIGLITVANAILVGYISW-----------SVYT 648
               :|..:|.       |:.|.: |.....:.|...|.:.|.:....|.|           .|.|
Mouse   479 ---NYGTHNH-------CWLSLHRGFIWSFLGPAAAIILINLVFYFLIIWILRSKLSSLNKEVST 533

  Fly   649 ALFKRDLIFKQLGLFVLLFFLLGITWIFGLCTYFDFGR----IFAYLFCLTATLQGFVLFLYFIV 709
            ....:.:.||.    ::..|:||.:|..||..:.:.|:    |.||||.:...|||.::|:...:
Mouse   534 LQDTKVMTFKA----IVQLFVLGCSWGIGLFIFIEVGKTVRLIVAYLFTIINVLQGVLIFMVHCL 594

  Fly   710 FNKE---NQRAWLGLCCNSSKKRNQQTIQMPTDSILQGLSHSSTNS 752
            .|::   ..:.|.            ..::...:|....:|||:|::
Mouse   595 LNRQVRMEYKKWF------------HRLRKEVESESTEVSHSTTHT 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	57/256 (22%)
Adgre4	NP_631877.2	EGF_CA	77..>105	CDD:214542	9/31 (29%)
		GAIN	<214..262	CDD:293098	8/47 (17%)
		GPS	290..332	CDD:280071	11/48 (23%)
		7tm_4	343..588	CDD:304433	69/284 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810