Protein Alignment Ktch and LOC4576098

DIOPT Version :10

• Sequence 1: NP_651845.2
• Gene: Ktch / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_001237342.4
• Gene: LOC4576098 / 4576098
• VectorBaseID: AGAMI1_013637
• Length: 1351
• Species: Anopheles gambiae
• Alignment Length: 772
• Identity: 221/772 - (28%)
• Similarity: 353/772 - (45%)
• Gaps: 156/772 - (20%)

  Fly    94 RVGQKANLRDLCLNER-GIPIRRRCQIRNGNRV------WQSLDHVTCRSAPELSSSINLLAVKS 151
            |:|:....|:|||.|: |:|:.|||.   |:.:      |.....:........:|::...:|.|
Mosquito   603 RLGESVAPRNLCLIEQSGLPVTRRCL---GDYLYGCAWDWNPGSELCTGQHRPTTSALYQYSVTS 664

  Fly   152 PPDMISQLSNLLTQTQEKLAA------ADVFSISEIFDSLVKKPERN---------AAVVGDLMK 201
            ...  |.|..:||:..|.||.      ||:|.:|:..:::....|::         .|...::..
Mosquito   665 LNH--SVLGEVLTRAGEILAVPEQVIPADLFYLSKTLENVPPVLEQSETGSPDEVRRAYFCNVST 727

  Fly   202 ICQKVMSTDNETLRVSADA-NATNALLSNFEDYLDELSPTILKLNTTIFANSTEFTF-------- 257
            |..:||..:..|:.:|..| |.||.||...|..::.|:          .||.|....
Mosquito   728 ILSRVMYLNETTVVLSQRALNTTNILLDATETIVNRLA----------VANDTRAMMLAGDQYDC 782

  Fly   258 ---------HPLFDMGVIVLKTSELRVFFVDPEVRNVSGIVNFSGGNMSHFEM------------ 301
                     |.....|.::.:|:.|.|...||.|.||:|:..|...|:|..::
Mosquito   783 RDRGGAIQRHVQRHDGTVLFRTARLIVLIADPTVANVTGLALFRARNLSLEDLSDAAENSESEED 847

  Fly   302 --------LHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRKGASY-------------------- 338
                    |:::.:.||:.|..:||...|||:.:...|.....::
Mosquito   848 FSGYTLRYLYMNQSLEDLLAESDLEIGSFIPQHVIEGLDELNTAFRAPDDEEQDPDAPDESTTTL 912

  Fly   339 -------------------LVFKVYTRDSLFVETEEEIKRRPTSNVISITIPGLNDTKLPGKLPF 384
                               ::..:|..|..|.||:.....||.|.:||:::||.. :::|.::|.
Mosquito   913 PSPGEHPDPPVSPAPPPLRVIITIYYNDHAFRETKNGTIARPNSKIISVSLPGYG-SRMPDEIPI 976

  Fly   385 FLRNAKANETQFEGGCGYWNYETWLSDGISTSGGGS------LEASSHPVILCHADHLTQFTFL- 442
            :.|..   ..:....||||::|   :|..:..|..|      |.||...|.||...|||.|:.|
Mosquito   977 YTREM---ARELPSRCGYWSFE---ADNATEFGHWSYDECRLLNASDRGVSLCGCFHLTSFSRLT 1035

  Fly   443 --------LGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKILL 499
                    :|||:.   |..::...:||:||.:|.::||||::.||.|||:|.|:|..||:||||
Mosquito  1036 KDIQMVETVGVSQK---LIADQGTLALDIITAIGCSMSLLGVMGIFATAALFPSWRVKASSKILL 1097

  Fly   500 NLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRV 564
            .|..|:.::::  :|..:...::|...|:.| |.|:|.:..|::||.|.||.|..:||:.|||:|
Mosquito  1098 QLSCAIAIEMI--IIFLEGPDIDQNRISQIE-CALLGGIFHYIILVTFMWMLITAYLQFMRYVKV 1159

  Fly   565 IGVNHPRHYILMSAVAAWTLPLIPTLLVVFLEPGSYRPNNSSMDYPILCYPSGYGLSLGVILPIG 629
            :|...|.|:||.:.|..|..||:...|.:.|:...|...::..|   :|||.|..|..|::||||
Mosquito  1160 LGQLRPAHFILKATVCCWGGPLLIVALFLSLDYTLYLKRDNLSD---ICYPHGRALWYGLLLPIG 1221

  Fly   630 LITVANA---ILVGYISWSVYTALFK---RDLIFKQLGLFVLLFFLLGITWIFGLCTYFDFGRIF 688
            .|...|.   ::|.|...::.:.|.|   ..:...||.|.|.||||||:.||||:.|.....::|
Mosquito  1222 AIIFVNLVSFVIVLYHICTIPSNLTKSADHAMTLAQLRLSVFLFFLLGLPWIFGMLTTGTEEKLF 1286

  Fly   689 AYLFCLTATLQGFVLFLYFIVFNKENQRAWLGL-----CCNSSKKRNQQTIQMPTDS 740
            ||||||||.:||||||:||:|.:...:|.|...     ||.:...::....|..|.:
Mosquito  1287 AYLFCLTAPVQGFVLFVYFVVMDPSARRFWCRKLQRLPCCRARPTKDADADQTTTSA 1343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktch	NP_651845.2	7tmB2_Adhesion	458..718	CDD:320168	108/265 (41%)
		TM helix 1	460..485	CDD:320168	13/24 (54%)
		TM helix 2	495..517	CDD:320168	7/21 (33%)
		TM helix 3	533..559	CDD:320168	11/25 (44%)
		TM helix 4	574..594	CDD:320168	7/19 (37%)
		TM helix 5	617..646	CDD:320168	11/31 (35%)
		TM helix 6	656..682	CDD:320168	15/25 (60%)
		TM helix 7	686..711	CDD:320168	18/24 (75%)
LOC4576098	XP_001237342.4	None