Protein Alignment CG15556 and Adgrf2

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_017173054.1
• Gene: Adgrf2 / 435529
• MGIID: 2182728
• Length: 673
• Species: Mus musculus
• Alignment Length: 775
• Identity: 162/775 - (20%)
• Similarity: 266/775 - (34%)
• Gaps: 234/775 - (30%)

  Fly    37 YCHLKNLRFLLCVDADGQLSHNPYKDCNRGFCKAEDFELEYETDEGKEKRINRVEKTRVGQKANL 101
            ||    |..||           |.:.| |..|:|        :.:.|||..:|.
Mouse     8 YC----LMLLL-----------PIESC-RILCQA--------SSKSKEKVTSRP----------- 37

  Fly   102 RDLC---LNERGIPIRRRC-QIRNGN-------RVWQSLDHVTCRSAPELS---SSINLLAVKSP 152
            .|:|   .|..|.|..:.| ....||       :.|..:.. ||.:....|   ....|.:|:|.
Mouse    38 HDVCDGVCNNNGTPCFQSCPPDSEGNMKFACKAKKWHKVTE-TCHTLNTHSIFEEDKELYSVQSS 101

  Fly   153 PDMI------SQLSNLLTQTQEKLAAADVFSISEIFDSLVKKPER--NAAVVGDLMKICQKVMST 209
            ...|      .:|..::....||...    .:|.:...:.:.|..  |.|||..|:......::.
Mouse   102 DSTIRTHMFHRELKTIMDTLMEKCPK----DLSCVIKGIERSPRMPGNIAVVVQLLHNISTTLTK 162

  Fly   210 D-NETLRVSADANATNAL----LSNFEDYLDELSPTILKLNTTIFANSTEFTFHPLFDMGVIVLK 269
            | ||....|..|.|.:.|    :||:....|..|..:|..:...||:.
Mouse   163 DVNEEKMQSYSAMANHILNSKSISNWTFIQDRNSSCVLLQSIHSFASK----------------- 210

  Fly   270 TSELRVFFVDPEVRNVSGIVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRK 334
                  .|:...:.|:|.:...:.|.:.....|.           ||...::.|.|   |..|..
Mouse   211 ------LFMKEHLINISHVFIHTLGTVVSRGSLG-----------KNFTFSMRINE---TSDKVT 255

  Fly   335 GASYLVFKVYTRDSLFVETEEEIKRRPTS-NVISITIPGL--------------NDTKLPGKLPF 384
            |...|             :.||:::.|:: .||||..|.|              |...|...||.
Mouse   256 GRLLL-------------SPEELQKVPSAFQVISIAFPTLGAILEASLLENVTVNGLVLSVILPE 307

  Fly   385 FLRN--------AKANETQFEGGCGYWNYETWLSDGISTSGGGSLEA-------------SSHPV 428
            .|:|        .|:.|.:.:  |..|:               |||:             |...|
Mouse   308 ELKNISLIFEKIRKSGERKSQ--CVGWH---------------SLESRWDWRACKTIQENSRQAV 355

  Fly   429 ILCHADHL-TQFTFLLGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAAVFKSFRTL 492
            ..|..:.| |.|:.|:..:.:::.:        |..||.:||.:|:..|::......:..|..|.
Mouse   356 CRCRPNKLYTSFSILMSPNTLESPV--------LTYITYIGLGISICSLIICLAIEVLVWSQVTK 412

  Fly   493 ASTKILLNLCAA-LGLQLL----FFLILS--QSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWM 550
            .....|.:||.| :...||    :|::.|  ...:|..      ..|......:.:..|.||.||
Mouse   413 TEISYLRHLCIANIAATLLMADAWFIVASFLSGPVLHH------NGCVAATFFVHFFYLSVFFWM 471

  Fly   551 ------FIIGFLQYQRYVRVIGVNHPRHYILMSAVA-AWTLPLIPTLLVVFL-EPGS--YRPN-- 603
                  .:.|.|       ::....|:..::.|..: .:..||:..::.:.: |||.  .||.
Mouse   472 LAKALLILYGIL-------IVFHTLPKSCLVASLFSVGYGCPLVIAIITLAVTEPGKGYLRPEAC 529

  Fly   604 --NSSMDYPILCYPSGYGLSLGVILPIGLITVANAILVGYISWSVYTALFKRDLIFKQLGLFV-- 664
              |..|...:|.:          ::|...|.|.|.|.|..:......|.....: |:::...|
Mouse   530 WLNWDMTKALLAF----------VVPALAIVVVNLITVTMVIIKTQRAAIGSSM-FQEVRAIVRI 583

  Fly   665 -----LLFFLLGITWIFGLCTYFDFGRIFAY--LFCLTATLQGFVLFLYFIVFNKENQRA 717
                 :|..|||:||.||:.|..: |...|:  :|.|...||||.:.|:..:.:.:.:.|
Mouse   584 CKNIAILTPLLGLTWGFGIATVIN-GHSLAFHIIFSLLNALQGFFILLFGTILDPKIREA 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	57/251 (23%)
Adgrf2	XP_017173054.1	GPS	326..373	CDD:383024	12/63 (19%)
		7tmB2_GPR111_115	378..644	CDD:320660	66/298 (22%)
		TM helix 1	381..405	CDD:320660	7/23 (30%)
		TM helix 2	420..441	CDD:320660	6/20 (30%)
		TM helix 3	454..476	CDD:320660	5/21 (24%)
		TM helix 4	497..513	CDD:320660	3/15 (20%)
		TM helix 5	535..558	CDD:320660	7/32 (22%)
		TM helix 6	581..606	CDD:320660	10/24 (42%)
		TM helix 7	611..636	CDD:320660	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900