DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15556 and mthl6

DIOPT Version :9

Sequence 1:	NP_001247379.1	Gene:	CG15556 / 43681	FlyBaseID:	FBgn0039821	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_788473.1	Gene:	mthl6 / 38839	FlyBaseID:	FBgn0035789	Length:	480	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	59/277 - (21%)
Similarity:	111/277 - (40%)	Gaps:	46/277 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   460 SLDVITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKILLNLC--AALGLQLLFFLILSQSHLLE 522
            |:..:..|| |:|::|.:   :|.||:...:.|.:   ||..|  ..:..:.:.:||.:...|
  Fly   201 SMPAVPQVG-TISMVGCI---LTIAVYLYIKKLRN---LLGKCFICYVFCKFVQYLIWAGGDL-- 256

  Fly   523 QLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMSAVAAWTLPLI 587
               ...:..|:|.|....:..|....|:.::.. |..:.:|:|..:...::.|:..:..|..|.|
  Fly   257 ---NLWNNICSLAGYTNYFFALASHFWLSVMSH-QIWKNLRLINRDERSYHFLIYNIYGWGTPAI 317

  Fly   588 PTLLVVFLE---------------PGSYRPNNSSMDYPILCYPSGYGLSLGVILPIGLITVANAI 637
            .|.:...::               .|.||...::.|:..:.|..|..|.|.:...:..|...|.|
  Fly   318 MTAITYLVDWAWEDRPDKLNWIPGVGLYRCWINTYDWSAMIYLYGPMLILSLFNVVTFILTVNHI 382

  Fly   638 LVGYISWSVYTALFKRDLIFKQLGLFVLLFFLLGITWIFGLCTYF----DFGR------IFAYLF 692
            :....|....|...::.:......|::.|..::|:|.|..:.|||    .|.|      .|.:|.
  Fly   383 MKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVTGISEVITYFVKRHKFWRQVLRVPNFFHLG 447

  Fly   693 CLTATLQGFVLFLYFIV 709
                  .|.|:|:.||:
  Fly   448 ------SGIVVFVLFIL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	49/248 (20%)
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403
mthl6	NP_788473.1	7tm_4	211..398	CDD:304433	38/198 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462188
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830