Protein Alignment CG15556 and Adgrg5

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001139444.1
• Gene: Adgrg5 / 382045
• MGIID: 2685955
• Length: 524
• Species: Mus musculus
• Alignment Length: 588
• Identity: 123/588 - (20%)
• Similarity: 219/588 - (37%)
• Gaps: 151/588 - (25%)

  Fly   170 LAAADVFSISEIFDSLVKKPERNAAVVGDLMKICQKVMSTDNETLRVSADANATNALLSNFEDYL 234
            |.||.|..:..:.|.||........|...|....:.:.|.:.:.|..|...:......::.:..:
Mouse    13 LLAAQVVLVETLSDLLVLMKRLEQPVGRGLSSRARHIHSLEQKLLNASFGGHNLTLQTNSIQSLV 77

  Fly   235 DELSPTI--LKLNTTIFANSTE------FTFHPLFDMGVIVL-KTSELRVFFVDPEVRNVSGIVN 290
            .:||...  |.|::|...|.::      ..|......|..|. :.:|||:..:
Mouse    78 FKLSCDFPGLSLSSTTLTNVSQVRAPHAMQFPAELTKGACVTSRPAELRLICI------------ 130

  Fly   291 FSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRKGASYLVFKVYTRDSLFVETEE 355
                   :|...||..::.:...:.|                     |::             ..
Mouse   131 -------YFFTAHLFQDDRNSSLLNN---------------------YVL-------------GA 154

  Fly   356 EIKRRPTSNVISITIPGLNDTKLPGKLPFFLRNAKANETQFEG---GCGYW-------NYETWLS 410
            ::..||.:|:           :.|..:.|:      :....||   .|.:|       ::..|..
Mouse   155 QLDHRPVNNL-----------QKPVNISFW------HNRSLEGYTVSCVFWKEGASKSSWGAWSP 202

  Fly   411 DGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVS--KMQAGLDTNEDDHSLDVITNVGLTLSL 473
            :|..|      |..|...:|||.:|||.|..|:.:|  .:.|.|..     .|:.|:.||.::|:
Mouse   203 EGCYT------EQPSATQVLCHCNHLTYFAVLMQLSGDPVPAELQV-----PLEYISFVGCSISI 256

  Fly   474 LGLLMIFITAAVFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAV 538
            :..|:..:..|..:. ::.::|:|.:||..::.|..:.||:.||.    .|.......|.::.||
Mouse   257 VASLLTILLYAQSRK-QSDSTTRIHMNLNGSVLLLNVTFLLSSQM----TLPTMPRPVCKVLAAV 316

  Fly   539 MQYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMSAVAAWTLPLIPTLLVVFLEPGSYRP- 602
            :.|.||...:||.|.||..|....||... :.|.|:|...:..|..|.:..||::.::...|.|
Mouse   317 LHYALLSSLTWMAIEGFNLYLFLGRVYNA-YIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPC 380

  Fly   603 ---------NNSSMDYPILCY----------PSGYGLSLGVILPIGLITVANAILVGYISWSVYT 648
                     |.:......:|:          ..|||         |..::.|.:::.:..| :..
Mouse   381 VTSLSKSQENGTGFQNVSMCWIRSPMVHSILVMGYG---------GFTSLFNLVVLAWALW-ILC 435

  Fly   649 ALFKRD-----LIFKQLGLFVLLFFLLGITWIFGLCTYFDFGRIF----AYLFCLTATLQGFVLF 704
            .|..|:     ..::...:.:.|..|||.||..   .:|.|| :|    .:||.:..:|.||.||
Mouse   436 RLRAREKALSPWAYRDTAMVLGLTVLLGTTWTL---AFFSFG-VFLLPQLFLFTIFNSLYGFFLF 496

  Fly   705 LYF 707
            |:|
Mouse   497 LWF 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	59/250 (24%)
Adgrg5	NP_001139444.1	GPS	184..228	CDD:366827	14/49 (29%)
		7tm_GPCRs	242..514	CDD:391938	69/283 (24%)
		TM helix 1	244..268	CDD:341315	6/23 (26%)
		TM helix 2	277..298	CDD:341315	7/20 (35%)
		TM helix 3	311..333	CDD:341315	8/21 (38%)
		TM helix 4	353..369	CDD:341315	3/15 (20%)
		TM helix 5	405..428	CDD:341315	5/31 (16%)
		TM helix 6	449..474	CDD:341315	7/27 (26%)
		TM helix 7	478..503	CDD:341315	9/22 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6570
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12011
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000