Protein Alignment CG15556 and ADGRD2

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001382354.1
• Gene: ADGRD2 / 347088
• HGNCID: 18651
• Length: 982
• Species: Homo sapiens
• Alignment Length: 705
• Identity: 141/705 - (20%)
• Similarity: 266/705 - (37%)
• Gaps: 169/705 - (23%)

  Fly    96 GQKANLRDLCLNE-------RGIPIRRRCQIRNGNRVWQSLDHVTCRSAPELSSSINLLAVKSPP 153
            |.::...:|||..       |..|.||....::    |...|.::..:|  |::.|.||     |
Human   330 GPRSEGSELCLEPQPFLCCYRTEPYRRLQDAQS----WPGQDVISRVNA--LANDIVLL-----P 383

  Fly   154 DMISQLSNLLTQTQEKLAAADVFSISEIFDSLVKKPERNAAVVGDLMKICQKVMSTDNETLRVSA 218
            |.:|::...|:..:    |:....:.|...::...|...||::. :::..::|         |:.
Human   384 DPLSEVHGALSPAE----ASSFLGLLEHVLAMEMAPLGPAALLA-VVRFLKRV---------VAL 434

  Fly   219 DANATNALLSNFEDYLDELSPTILKLNTTIFANSTEFTFHPLFDM--GVIVLKTSELRVFFVDPE 281
            .|.....||:.   ..::||..::.:.:.:.......|:..|.::  |.:.|..|
Human   435 GAGDPELLLTG---PWEQLSQGVVSVASLVLEEQVADTWLSLREVIGGPMALVAS---------- 486

  Fly   282 VRNVSGIVNFS-GGNMSHFEMLHLSDNEEDIRAMKNLESA------------------VFIPEKL 327
            |:.::.:::.| ........:.|.....| :|:::..|::                  :.||...
Human   487 VQRLAPLLSTSMTSERPRMRIQHRHAGLE-VRSLRLREASTRGCLFTMPGGRPEGPGHIHIPASE 550

  Fly   328 WTQLKRKGASYLVFKVYTRDSLFVETEEEIKRRPTSNVISITIPGLN-DTKLPGKLPFFLRNAKA 391
            ..:|.|||.|    .|....|.|           ||.|...|:.|.: :.:.|..      :.:|
Human   551 VRRLLRKGLS----GVTVIHSWF-----------TSRVFQHTLEGPDLEPQAPAS------SEEA 594

  Fly   392 NETQ----FEGGCGYWNYETW------------------------------LSDGISTSGGGSLE 422
            |..|    .:.|....:.|.|                              .:.|...:.|.|:.
Human   595 NRVQRFLSTQVGSAIISSEVWDVTGEVNVAMTFHLQHRAQSPLFPPHPPSPYTGGAWATTGCSVA 659

  Fly   423 ASSHPVILCHADHLTQFTFLLGVSKMQAGLDTNEDDHSLDVITNVGLTLSLLGL---LMIFITAA 484
            |.......|..:|.|.|..||.:.::|.|   .|::..|..::.||..:|...|   .::|:.|.
Human   660 ALYLDSTACFCNHSTSFAILLQIYEVQRG---PEEESLLRTLSFVGCGVSFCALTTTFLLFLVAG 721

  Fly   485 VFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSW 549
            |.||.||.....:..:|.:|.|     ||:.|      :..::....|..|...|.:|.||.|||
Human   722 VPKSERTTVHKNLTFSLASAEG-----FLMTS------EWAKANEVACVAVTVAMHFLFLVAFSW 775

  Fly   550 MFIIGFLQYQRYVRVIGVNHPRHYILMSAVAAWTLPLIPTLLVVFLEPGSY-RPNNSSMDYPILC 613
            |.:.|.|.:::.|.|  ..||...:.:.....|.:|:....:.:.:.|..| .|.:        |
Human   776 MLVEGLLLWRKVVAV--SMHPGPGMRLYHATGWGVPVGIVAVTLAMLPHDYVAPGH--------C 830

  Fly   614 YPSGYGLSLGVIL-PIGLITVAN-AILVGYISWSVYTALFKRDLIFKQLGL-------------- 662
            :.:.:..::...: |:..:..|| .||...:..:|.:|..:..::..|..|
Human   831 WLNVHTNAIWAFVGPVLFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQIWTQIWATVKP 895

  Fly   663 FVLLFFLLGITWIFGLCTYFDFGRIFAYLFCLTATLQGFVLFLYFIVFNKENQRA 717
            .::|..:||:||:.|:..:  ....:||......::||..:||.:...|:|.:.|
Human   896 VLVLLPVLGLTWLAGILVH--LSPAWAYAAVGLNSIQGLYIFLVYAACNEEVRSA 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	53/238 (22%)
ADGRD2	NP_001382354.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810