Protein Alignment CG15556 and ADGRF1

DIOPT Version :9

• Sequence 1: NP_001247379.1
• Gene: CG15556 / 43681
• FlyBaseID: FBgn0039821
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_722582.2
• Gene: ADGRF1 / 266977
• HGNCID: 18990
• Length: 910
• Species: Homo sapiens
• Alignment Length: 823
• Identity: 170/823 - (20%)
• Similarity: 295/823 - (35%)
• Gaps: 205/823 - (24%)

  Fly     8 IAGYIILVSGGTNPPLYALDQPNVARCLDYCHLKNLRFLLCVDADGQLSHNPYKDCNR---GFCK 69
            :|||.::.|...:..|.|::  :||.     ..|.....|....||.........||.   ||..
Human   209 VAGYEVVGSSSASELLSAIE--HVAE-----KAKTALHKLFPLEDGSFRVFGKAQCNDIVFGFGS 266

  Fly    70 AEDFELEYETDEGKEKRINRVEKTRVGQKANLRDLCLNERGIPIRRRCQIRNGNRVWQSLD---- 130
            .:|   ||........|.|...|........:|:.|:......:.:...:..||....::.
Human   267 KDD---EYTLPCSSGYRGNITAKCESSGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQ 328

  Fly   131 --HVTCRSAPELSSSINLLAVKSPPDMISQLSNLLTQTQEKLAAADVFSISEIFDSLVKKPERNA 193
              .|..|..|  |:::..||     .::|.|||:     ..|:.|..|.:|.
Human   329 NLSVIIRQNP--STTVGNLA-----SVVSILSNI-----SSLSLASHFRVSN------------- 368

  Fly   194 AVVGDLMKICQKVM---STDNETLRVSADANATNALLSNFEDYLDELSPTILKLNTTIFANSTEF 255
            :.:.|::.|...::   |..|.|:.:..:..|::.||...|:....:.||.|.||.     |.:|
Human   369 STMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNF-----SRKF 428

  Fly   256 TFHPLFDMGVIVLKTSELRVFFVDPEVRNVSGIVNFSGGNMS---HFEMLHLSDN-----EEDIR 312
                 .|...|.:..|:|:        |..|..:.....|.|   ...:|..||.     .|.|.
Human   429 -----IDWKGIPVNKSQLK--------RGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETII 480

  Fly   313 AMKNLESAVFIPEKLWTQLKRKGASYLVFKVYTRDSLFVETEEEIKRRPTSNVISITIPGLNDTK 377
            :|.:|.....:|      :.:.|.:.:                      ...|||..|...:..:
Human   481 SMASLTLGNILP------VSKNGNAQV----------------------NGPVISTVIQNYSINE 517

  Fly   378 LPGKLPFFLRNAKANETQFEGGCGYWNYE--TWLSDGISTSGGGSLEASSHPVILCHADHLTQFT 440
            :      ||..:|......:..|.:|::.  .|      ...|..|...:..::.|...|||.|:
Human   518 V------FLFFSKIESNLSQPHCVFWDFSHLQW------NDAGCHLVNETQDIVTCQCTHLTSFS 570

  Fly   441 FLLG---------VSKMQAGLDTNEDDHSLDVITNVGLTLSLLGLLMIFITAAVF----KSFRTL 492
            .|:.         |.|.               ||.|||.:|:..|::..|..|:|    |..:|.
Human   571 ILMSPFVPSTIFPVVKW---------------ITYVGLGISIGSLILCLIIEALFWKQIKKSQTS 620

  Fly   493 ASTKI-LLNLCAALGLQLLFFLILSQSHLLEQLEQSESERCTLVGAVMQYLLLVVFSWMFIIGFL 556
            .:.:| ::|:..:|.:..::|::    ........:.|..||.......:..|.:|.||.::|.|
Human   621 HTRRICMVNIALSLLIADVWFIV----GATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGIL 681

  Fly   557 QYQRYVRVIGVNHPRHYILMSA--VAAWTLPLIPTLLVVFLEPGSYRPNNS--SMDYPILCYPSG 617
            ...|.:.|.  :|...:::|:.  ...:..|||.:::.:.:.    :|:|:  ..|...|.:.:|
Human   682 LAYRIILVF--HHMAQHLMMAVGFCLGYGCPLIISVITIAVT----QPSNTYKRKDVCWLNWSNG 740

  Fly   618 YGLSLGVILPIGLITVANAILVGYISWSVYTALFK--------RD---LIFKQLGLFVLLFFLLG 671
            ....|..::|...|...|.::|    ..|.|.|::        ||   .|.:.....::|..|||
Human   741 SKPLLAFVVPALAIVAVNFVVV----LLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLG 801

  Fly   672 ITWIFGLCTYFDFGRI-FAYLFCLTATLQGFVLFLYFI---------VFNK----------ENQR 716
            :||.||:.|..|...: :..:|.|....|||.:..:.|         :|||          |.|
Human   802 LTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQ- 865

  Fly   717 AWLGLCCNSSKKRNQQTIQMPTDSILQ----GLSHSSTNSTSI 755
                   |||....:.....|.:.:..    ..||:..:|.:|
Human   866 -------NSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDNI 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	56/242 (23%)
ADGRF1	NP_722582.2	SEA	154..>215	CDD:279699	3/5 (60%)
		GPS	532..572	CDD:280071	10/45 (22%)
		7tm_4	582..834	CDD:304433	65/280 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810