DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15556 and Adgrg7

DIOPT Version :9

Sequence 1:	NP_001247379.1	Gene:	CG15556 / 43681	FlyBaseID:	FBgn0039821	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_766413.2	Gene:	Adgrg7 / 239853	MGIID:	2441732	Length:	785	Species:	Mus musculus

Alignment Length:	743	Identity:	161/743 - (21%)
Similarity:	285/743 - (38%)	Gaps:	215/743 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LNERGIPIRRRCQIRN-GNRVWQSLDHVTCRSAPELSSSINLLAVK-------SPPDMISQLSNL 162
            ||.......|.|.:.. ||...|::...:|        :|||..::       :..:.||:.:.:
Mouse   110 LNAGSPKATRLCNVSEFGNIELQNVTKGSC--------NINLQTLEIQINNQTASAENISREAQV 166

  Fly   163 LTQTQEKLAAADVFS----ISEIF-----DSLVKKPERNAAVVGDLM----KICQKVMSTDNETL 214
            ||....||.|.::.|    :.:||     :|..||..  .|.|..::    .:.||....||
Mouse   167 LTADASKLTAQNITSATTVVGQIFGKANNESQAKKTA--IATVSQILDASEDVFQKAAEMDN--- 226

  Fly   215 RVSADANATNALLSNFEDY-LDELSPTILKLNTTIFANSTEFTFHP--LFDMGVIVLKTSELRVF 276
                 :.:.:.|:...|:| ..:...|:::.|..|.:.:.:....|  ||.    |.|.|...:
Mouse   227 -----SKSFSNLIKQMENYSYSQGDQTVVEPNIAIQSVTRDDNSGPSVLFS----VQKGSSNSL- 281

  Fly   277 FVDPEVRNVSG--IVNFSGGNMSHFEMLHLSDNEEDIRAMKNLESAVFIPEKLWTQLKRKGASYL 339
                    |||  ::|.:...::       .|.:.:::.:.|            |...||...::
Mouse   282 --------VSGRILINKTANGLN-------PDGQTELQILLN------------TGENRKSCGFM 319

  Fly   340 VF--------KVYTRDSLFVE-------TEEEIKRRPTSNVISITIPGLNDTKLPGKLPFFLRNA 389
            |:        |.:|..|.|.:       .|.|.:|:...:|..:..|..:..:|  :|..:
Mouse   320 VYQNHKLFQSKTFTATSDFSQKIISSKINESEQQRQNKVSVEMVFNPTYDKREL--RLHSY---- 378

  Fly   390 KANETQFEGGCGYWNY--ETWLSDGISTSGGGSLEASSHPVILCHADHLTQFTFLLGVSKMQAGL 452
                     .|.|||:  ..|.:.|...:|      ::...:.|:..|.|.|..|:...|
Mouse   379 ---------ACVYWNFLINDWDTQGCQKTG------NTTEFLRCNCSHTTNFAVLMSFKK----- 423

  Fly   453 DTNEDDH----SLDVITNVGLTLSLLGLLMIFITAAVFKSFRTLASTKILLNLCAA-LGLQLLFF 512
                 |:    |||:::|:|..||:.||.:..:...:.:..|..:.|.:|::||:: |...|||.
Mouse   424 -----DYKYPKSLDILSNIGCALSIAGLALTILFQILTRKIRKTSVTWVLVSLCSSMLIFNLLFV 483

  Fly   513 LILSQSHLLEQLEQSESE---------------------RCTLVGAVMQYLLLVVFSWMFIIGFL 556
            ..:..|:  :.|:.|:|:                     .||.:.|::.|.|||.|:|.   |..
Mouse   484 FGIENSN--KNLKTSDSDINVKPENNKIPESDTIETPNPSCTAIAALLHYFLLVTFTWN---GLS 543

  Fly   557 QYQRYVRVIGVNH--PRHYILMSAVAAWTLPLI---PTLLVVFLEPGSYRPNNSSMDY--PILCY 614
            ..|.|..:|....  |||:|:..::..|.:|.|   .|:..::...|:.|  ...:||  ..:|:
Mouse   544 ATQLYFLLIRTMKPLPRHFIIFISLVGWGVPAIIVGVTIGSIYALSGNKR--YWELDYRQEEICW 606

  Fly   615 -----PSGYG---LSLGVILPIGLITVANAILVGYISWSVYTALFKRD-------------LIFK 658
                 .:.|.   |....|:|:.:|.:.|..:...|:..|   |:|.:             .:|.
Mouse   607 LAVPKDNDYARSPLLWSFIIPVTIILITNITIFVIITVKV---LWKNNQNLTSTKKVSSLKKVFS 668

  Fly   659 QLGLFVLLFFLLGITWIFG---LCTYFDFGRIFAYLFCLTATLQGFVLFLYFIVFNKENQRAWLG 720
            .|.:.|    :.|:|||..   |.:..|...:|:|:|||..|.||..:|:.:.|..|
Mouse   669 TLSIAV----VFGVTWILAYAMLISNDDIRIVFSYIFCLFNTTQGLQIFILYTVRTK-------- 721

  Fly   721 LCCNSSKKRNQQTIQMPTDSILQGLSHS 748
                        ..|.....||:.||.|
Mouse   722 ------------VFQSEASKILKSLSSS 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	66/274 (24%)
Adgrg7	NP_766413.2	GPS	380..418	CDD:280071	11/43 (26%)
Adgrg7	NP_766413.2	7tm_4	430..710	CDD:304433	74/293 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870